Search Results - "Lloyd, Daniel G"

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA) by Malkawi, Ruba, Iyer, Abhishek, Parmar, Anish, Lloyd, Daniel G, Leng Goh, Eunice Tze, Taylor, Edward J, Sarmad, Sarir, Madder, Annemieke, Lakshminarayanan, Rajamani, Singh, Ishwar

“…Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant…”
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The Myxobacterium Myxococcus xanthus Can Sense and Respond to the Quorum Signals Secreted by Potential Prey Organisms by Lloyd, Daniel G, Whitworth, David E

“…The myxobacterium is a predatory member of the soil microfauna, able to consume bacteria (Gram-negative, Gram-positive), archaea, and fungi. Many potential…”
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Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo by Parmar, Anish, Lakshminarayanan, Rajamani, Iyer, Abhishek, Mayandi, Venkatesh, Leng Goh, Eunice Tze, Lloyd, Daniel G, Chalasani, Madhavi Latha S, Verma, Navin K, Prior, Stephen H, Beuerman, Roger W, Madder, Annemieke, Taylor, Edward J, Singh, Ishwar

“…The cyclic depsipeptide, teixobactin, kills a number of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and Mycobacterium…”
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De Novo Resistance to Arg10-Teixobactin Occurs Slowly and Is Costly by Lloyd, Daniel G, Schofield, Benjamin J, Goddard, Matthew R, Taylor, Edward J

“…Bacterial pathogens are rapidly evolving resistance to all clinically available antibiotics. One part of the solution to this complex issue is to better…”
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Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres by Parmar, Anish, Iyer, Abhishek, Lloyd, Daniel G, Vincent, Charlotte S, Prior, Stephen H, Madder, Annemieke, Taylor, Edward J, Singh, Ishwar

“…The recently discovered cyclic depsipeptide, teixobactin, is a highly potent antibiotic against multi-drug resistant pathogens such as methicillin-resistant…”
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De Novo Resistance to Arg 10 -Teixobactin Occurs Slowly and Is Costly by Lloyd, Daniel G, Schofield, Benjamin J, Goddard, Matthew R, Taylor, Edward J

“…Bacterial pathogens are rapidly evolving resistance to all clinically available antibiotics. One part of the solution to this complex issue is to better…”
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Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding by Parmar, Anish, Iyer, Abhishek, Prior, Stephen H, Lloyd, Daniel G, Leng Goh, Eunice Tze, Vincent, Charlotte S, Palmai-Pallag, Timea, Bachrati, Csanad Z, Breukink, Eefjan, Madder, Annemieke, Lakshminarayanan, Rajamani, Taylor, Edward J, Singh, Ishwar

“…Teixobactin is a highly promising antibacterial depsipeptide consisting of four d-amino acids and a rare l- -enduracididine amino acid. l- -Enduracididine is…”
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Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II bindingElectronic supplementary information (ESI) available: Peptide synthesis, HPLC, LC-MS analysis, NMR spectra, microbiological data (MIC, MBC, time kill kinetics), lipid II and geranyl pyrophosphate binding, cytotoxicity assay. See DOI: 10.1039/c7sc03241b by Parmar, Anish, Iyer, Abhishek, Prior, Stephen H, Lloyd, Daniel G, Leng Goh, Eunice Tze, Vincent, Charlotte S, Palmai-Pallag, Timea, Bachrati, Csanad Z, Breukink, Eefjan, Madder, Annemieke, Lakshminarayanan, Rajamani, Taylor, Edward J, Singh, Ishwar

“…Teixobactin is a highly promising antibacterial depsipeptide consisting of four d -amino acids and a rare l - allo -enduracididine amino acid. l - allo…”
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Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding† †Electronic supplementary information (ESI) available: Peptide synthesis, HPLC, LC-MS analysis, NMR spectra, microbiological data (MIC, MBC, time kill kinetics), lipid II and geranyl pyrophosphate binding, cytotoxicity assay. See DOI: 10.1039/c7sc03241b by Parmar, Anish, Iyer, Abhishek, Prior, Stephen H., Lloyd, Daniel G., Leng Goh, Eunice Tze, Vincent, Charlotte S., Palmai-Pallag, Timea, Bachrati, Csanad Z., Breukink, Eefjan, Madder, Annemieke, Lakshminarayanan, Rajamani, Taylor, Edward J., Singh, Ishwar

“…Leu 10 -teixobactin and Ile 10 -teixobactin have shown comparable activity to natural teixobactin. Teixobactin is a highly promising antibacterial depsipeptide…”
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