Search Results - "Llorente, Cristina"
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The Imperative for Innovative Enteric Nervous System-Intestinal Organoid Co-Culture Models: Transforming GI Disease Modeling and Treatment
Published in Cells (Basel, Switzerland) (10-05-2024)“…This review addresses the need for innovative co-culture systems integrating the enteric nervous system (ENS) with intestinal organoids. The breakthroughs…”
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Isolation of Myenteric and Submucosal Plexus from Mouse Gastrointestinal Tract and Subsequent Co-Culture with Small Intestinal Organoids
Published in Cells (Basel, Switzerland) (10-05-2024)“…Intestinal homeostasis results from the proper interplay among epithelial cells, the enteric nervous system (ENS), interstitial cells of Cajal (ICCs), smooth…”
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Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223
Published in The Journal of clinical investigation (01-10-2019)“…Persistent, unresolved inflammation in the liver represents a key trigger for hepatic injury and fibrosis in various liver diseases and is controlled by…”
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Pyroptosis by caspase11/4‐gasdermin‐D pathway in alcoholic hepatitis in mice and patients
Published in Hepatology (Baltimore, Md.) (01-05-2018)“…Alcoholic hepatitis (AH) continues to be a disease with high mortality and no efficacious medical treatment. Although severe AH is presented as acute on…”
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Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation
Published in Cell host & microbe (10-02-2016)“…Approximately half of all deaths from liver cirrhosis, the tenth leading cause of mortality in the United States, are related to alcohol use. Chronic alcohol…”
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Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice
Published in Hepatology (Baltimore, Md.) (01-06-2018)“…Alcoholic liver disease (ALD) is associated with changes in the intestinal microbiota. Functional consequences of alcohol‐associated dysbiosis are largely…”
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Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus
Published in Nature communications (16-10-2017)“…Chronic liver disease is rising in western countries and liver cirrhosis is the 12th leading cause of death worldwide. Simultaneously, use of gastric acid…”
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Prognostic impact of number of induction courses to attain complete remission in patients with acute myeloid leukemia transplanted with either a matched sibling or human leucocyte antigen 10/10 or 9/10 unrelated donor: An Acute Leukemia Working Party European Society for Blood and Marrow Transplantation study
Published in Cancer (01-08-2024)“…Introduction For the majority of patients with acute myeloid leukemia (AML) an allogeneic stem cell transplant (SCT) in first complete remission (CR) is…”
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CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease
Published in Nature communications (09-12-2021)“…Complement receptor of immunoglobulin superfamily (CRIg) is expressed on liver macrophages and directly binds complement component C3b or Gram-positive…”
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Goblet cells: guardians of gut immunity and their role in gastrointestinal diseases
Published in eGastroenterology (01-10-2024)“…Goblet cells (GCs) are specialised guardians lining the intestine. They play a critical role in gut defence and immune regulation. GCs continuously secrete…”
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Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity
Published in American journal of physiology: Gastrointestinal and liver physiology (01-03-2016)“…Nonalcoholic fatty liver disease (NAFLD) and obesity are characterized by altered gut microbiota, inflammation, and gut barrier dysfunction. Here, we…”
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Haematopoietic stem cell transplantation for severe autoimmune diseases in children: A review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation
Published in British journal of haematology (01-07-2022)“…Summary Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over…”
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Adipocyte SIRT1 knockout promotes PPAR γ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity
Published in Molecular metabolism (Germany) (01-05-2015)“…Abstract Objective Adipose tissue is the primary site for lipid deposition that protects the organisms in cases of nutrient excess during obesogenic diets. The…”
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Antibody response after 2 and 3 doses of SARS-CoV-2 mRNA vaccine in allogeneic hematopoietic cell transplant recipients
Published in Blood (06-01-2022)“…Three reports address the protection of the vulnerable population of patients with hematologic malignancies in the face of the ongoing COVID pandemic. The…”
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Phase II clinical trial for the evaluation of bortezomib within the reduced intensity conditioning regimen (RIC) and post‐allogeneic transplantation for high‐risk myeloma patients
Published in British journal of haematology (01-08-2013)“…Summary The current study was designed to assess the safety and efficacy of bortezomib in combination with fludarabine and melphalan as reduced intensity…”
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Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis
Published in Osteoarthritis and cartilage open (01-09-2022)“…Inflammatory responses are associated with changes in tissue metabolism. Prior studies find altered metabolomic profiles in both the synovial fluid (SF) and…”
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When monoclonal gammopathy‐associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes
Published in EJHaem (01-08-2023)“…According to World Health Organization (WHO) classification, presence of a plasma cell disorders (PCDs) should be investigate to avoid CNL misdiagnosis…”
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Molecular Landscape of Therapy‐related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers
Published in HemaSphere (01-09-2021)“…Definition of therapy‐related myeloid neoplasms (TRMN) is only based on clinical history of exposure to leukemogenic therapy. No specific molecular…”
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Colesevelam Reduces Ethanol-Induced Liver Steatosis in Humanized Gnotobiotic Mice
Published in Cells (Basel, Switzerland) (14-06-2021)“…Alcohol-related liver disease is associated with intestinal dysbiosis. Functional changes in the microbiota affect bile acid metabolism and result in elevated…”
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P1146: TRANSFUSION NEEDS AFTER CD19 CAR T‐CELLS FOR LARGE B‐CELL LYMPHOMA: PREDICTIVE FACTORS AND IMPACT ON OUTCOME. A DESCAR‐T STUDY
Published in HemaSphere (08-08-2023)Get full text
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