Search Results - "Llorens‐Martín, María"
-
1
Adult-born neurons in brain circuitry
Published in Science (American Association for the Advancement of Science) (10-05-2019)“…Immature and mature neurons connect in the hippocampus The mammalian hippocampus is often referred to as the gateway to memory formation. By receiving…”
Get full text
Journal Article -
2
GSK‐3β S9A overexpression leads murine hippocampal neural precursors to acquire an astroglial phenotype in vivo
Published in Developmental neurobiology (Hoboken, N.J.) (01-07-2021)“…The addition of new neurons to the existing hippocampal circuitry persists in the adult dentate gyrus (DG). During this process, named adult hippocampal…”
Get full text
Journal Article -
3
Methods to study adult hippocampal neurogenesis in humans and across the phylogeny
Published in Hippocampus (01-04-2023)“…The hippocampus hosts the continuous addition of new neurons throughout life—a phenomenon named adult hippocampal neurogenesis (AHN). Here we revisit the…”
Get full text
Journal Article -
4
The Role of Microglia in the Spread of Tau: Relevance for Tauopathies
Published in Frontiers in cellular neuroscience (10-07-2018)“…Tauopathies are neurodegenerative diseases which course with the accumulation of Tau, mainly in neurons. In addition, Tau accumulates in a hyperphosphorylated…”
Get full text
Journal Article -
5
Novel connection between newborn granule neurons and the hippocampal CA2 field
Published in Experimental neurology (01-01-2015)“…Newborn neurons are continuously added to the hippocampal dentate gyrus (DG) throughout life. Mature and immature granule neurons are believed to send their…”
Get full text
Journal Article -
6
Role of Neuroinflammation in Adult Neurogenesis and Alzheimer Disease: Therapeutic Approaches
Published in Mediators of Inflammation (01-01-2013)“…Neuroinflammation, a specialized immune response that takes place in the central nervous system, has been linked to neurodegenerative diseases, and specially,…”
Get full text
Journal Article -
7
GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner
Published in PloS one (14-11-2011)“…Mitochondrial trafficking deficits have been implicated in the pathogenesis of several neurological diseases, including Alzheimer's disease (AD). The Ser/Thre…”
Get full text
Journal Article -
8
Mifepristone prevents stress-induced apoptosis in newborn neurons and increases AMPA receptor expression in the dentate gyrus of C57/BL6 mice
Published in PloS one (30-11-2011)“…Chronic stress produces sustained elevation of corticosteroid levels, which is why it is considered one of the most potent negative regulators of adult…”
Get full text
Journal Article -
9
Antidepressant and Proneurogenic Influence of Environmental Enrichment in Mice: Protective Effects vs Recovery
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2011)“…Physical-cognitive activity has long-lasting beneficial effects on the brain and on behavior. Environmental enrichment (EE) induces brain activity known to…”
Get full text
Journal Article -
10
(New neurons) singing in the avian brain
Published in Nature reviews. Neuroscience (01-06-2023)“…In this Journal Club, María Llorens-Martín describes a 1983 paper that revealed ongoing neurogenesis in the brains of adult female canaries…”
Get full text
Journal Article -
11
Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis
Published in The Neuroscientist (Baltimore, Md.) (01-04-2009)“…This review addresses the role of serum insulin-like growth factor 1 (IGF1) as one mechanism of adult neural plasticity, specifically, its regulation of…”
Get full text
Journal Article -
12
Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus
Published in Brain, behavior, and immunity (01-03-2016)“…Highlights • Forced swimming impedes morphological and functional maturation of newborn neurons. • Forced swimming induces the functional and morphological…”
Get full text
Journal Article -
13
Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour
Published in Molecular and cellular neuroscience (01-06-2010)“…While physical exercise clearly has beneficial effects on the brain, fomenting neuroprotection as well as promoting neural plasticity and behavioural…”
Get full text
Journal Article -
14
Retroviral induction of GSK-3β expression blocks the stimulatory action of physical exercise on the maturation of newborn neurons
Published in Cellular and molecular life sciences : CMLS (01-09-2016)“…Adult hippocampal neurogenesis (AHN) is a key process for certain types of hippocampal-dependent learning. Alzheimer’s disease (AD) is accompanied by memory…”
Get full text
Journal Article -
15
The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology
Published in Frontiers in neuroscience (19-01-2016)“…Newborn neurons are continuously added to the hippocampal dentate gyrus throughout adulthood. In this review, we analyze the maturational stages that newborn…”
Get full text
Journal Article -
16
Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2018)“…Neurogenesis occurs in a limited number of brain regions during adulthood. Of these, the hippocampus has attracted great interest due to its involvement in…”
Get more information
Journal Article -
17
Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis
Published in Human molecular genetics (01-04-2013)“…Adult neurogenesis, the generation of new neurons during the adulthood, is a process controlled by several kinases and phosphatases among which GSK3β exerts…”
Get full text
Journal Article -
18
GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus
Published in Frontiers in neuroanatomy (10-03-2017)“…The dentate gyrus (DG) plays a crucial role in hippocampal-related memory. The most abundant cellular type in the DG, namely granule neurons, are…”
Get full text
Journal Article -
19
Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration
Published in Oncotarget (14-02-2017)Get full text
Journal Article -
20
ADULT HIPPOCAMPAL NEUROGENESIS, THE POST-MORTEM DELAY, AND PROLONGED ALDEHYDE FIXATION: THE ENEMIES WITHIN
Published in IBRO neuroscience reports (01-10-2023)Get full text
Journal Article