Search Results - "Llinás, Miguel"
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Human Plasminogen Kringle 3: Solution Structure, Functional Insights, Phylogenetic Landscape
Published in Biochemistry (Easton) (24-08-2010)“…Human plasminogen kringle 3 (hPgn K3) domain contains most elements of the canonical lysine-binding site (LBS) found in other Pgn kringles. However, it does…”
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CLOUDS, A Protocol for Deriving a Molecular Proton Density via NMR
Published in Proceedings of the National Academy of Sciences - PNAS (14-05-2002)“…We demonstrate the feasibility of computing realistic spatial proton distributions for proteins in solution from experimental NMR nuclear Overhauser effect…”
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3
Solution Structure and Functional Characterization of Human Plasminogen Kringle 5
Published in Biochemistry (Easton) (03-11-2009)“…The ligand binding properties of the kringle 5 (K5) domain of human plasminogen have been investigated via intrinsic tryptophan fluorescence. The oleic acid…”
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4
Conformational dynamics and ligand binding in the multi-domain protein PDC109
Published in PloS one (18-02-2010)“…PDC109 is a modular multi-domain protein with two fibronectin type II (Fn2) repeats joined by a linker. It plays a major role in bull sperm binding to the…”
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Deuterated Protein Folds Obtained Directly from Unassigned Nuclear Overhauser Effect Data
Published in Journal of the American Chemical Society (26-03-2008)“…We demonstrate the feasibility of determining the global fold of a highly deuterated protein from unassigned experimental NMR nuclear Overhauser effect (NOE)…”
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6
Protein Structure Elucidation from NMR Proton Densities
Published in Proceedings of the National Academy of Sciences - PNAS (14-05-2002)“…The NMR-generated foc proton density affords a template to which the molecule has to be fitted to derive the structure. Here we present a computational…”
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NMR Solution Structure of the Neurotrypsin Kringle Domain
Published in Biochemistry (Easton) (25-11-2008)“…Neurotrypsin is a multidomain protein that serves as a brain-specific serine protease. Here we report the NMR structure of its kringle domain, NT/K. The data…”
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La información turística online a escala local. Análisis de las webs oficiales de los ayuntamientos de Mallorca, España
Published in Investigaciones turísticas (01-01-2021)“…La búsqueda de información es un elemento clave a la hora de escoger un destino turístico, lo cual, provoca que la divulgación de información turística a…”
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Kringle 5 of Plasminogen is a Novel Inhibitor of Endothelial Cell Growth
Published in The Journal of biological chemistry (05-09-1997)“…Angiostatin is a potent angiogenesis inhibitor which has been identified as an internal fragment of plasminogen that includes its first four kringle modules…”
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Protein structure elucidation from minimal NMR data: the CLOUDS approach
Published in Methods in enzymology (2005)“…In this chapter we review automated methods of protein NMR data analysis and expand on the assignment-independent CLOUDS approach. As presented, given a set of…”
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Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis
Published in The FASEB journal (01-12-1998)“…ABSTRACT Angiogenesis is a complex process that involves endothelial cell proliferation, migration, basement membrane degradation, and neovessel organization…”
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12
Peptide Ligands for the Fibronectin Type II Modules of Matrix Metalloproteinase 2 (MMP-2)
Published in The Journal of biological chemistry (04-04-2003)“…The interaction of matrix metalloproteinase 2 (MMP-2) with gelatin is mediated by three repeats homologous to fibronectin type II (FN2) modules, which are…”
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The CCPN data model for NMR spectroscopy: Development of a software pipeline
Published in Proteins, structure, function, and bioinformatics (01-06-2005)“…To address data management and data exchange problems in the nuclear magnetic resonance (NMR) community, the Collaborative Computing Project for the NMR…”
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Representación del espacio urbano en alumnos de primaria de la ciudad de Bahía Blanca (Argentina). Un análisis a partir de mapas mentales
Published in Boletín de la Asociación de Geógrafos Españoles (05-12-2016)“…El presente trabajo tiene como objetivo: analizar la representación mental de alumnos de educación primaria de la ciudad de Bahía Blanca, a partir de la…”
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Structure-oriented methods for protein NMR data analysis
Published in Progress in nuclear magnetic resonance spectroscopy (01-05-2010)Get full text
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Sequence specific resonance assignment via Multicanonical Monte Carlo search using an ABACUS approach
Published in Journal of biomolecular NMR (01-05-2008)“…ABACUS [Grishaev et al. (2005) Proteins 61:36-43] is a novel protocol for automated protein structure determination via NMR. ABACUS starts from molecular…”
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El papel del clima en la estacionalidad turística y la configuración de productos turísticos emergentes. El caso de Mallorca
Published in Cuadernos de turismo (01-01-2014)“…La estacionalidad ha sido un fenómeno ampliamente abordado dentro de la literatura científica, especialmente a partir de planteamientos economicistas sobre sus…”
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Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug
Published in Journal of molecular biology (20-12-1991)“…The solution structure of a recombinant tissue-type plasminogen activator kringle 2 domain, complexed with the antifibrinolytic drug 6-aminohexanoic acid…”
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Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein
Published in Nature structural biology (01-04-2001)“…BAG-family proteins share a conserved protein interaction region, called the 'BAG domain', which binds and regulates Hsp70/Hsc70 molecular chaperones. This…”
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Deuterated Protein Folds Obtained Directly from Unassigned NOE Data
Published in Journal of the American Chemical Society (05-03-2008)“…We demonstrate the feasibility of determining the global fold of a highly deuterated protein from unassigned experimental NMR nuclear Overhauser effect (NOE)…”
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