Search Results - "Llinás, María T"
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Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats with a prolonged high fat diet from an early age
Published in PloS one (30-06-2020)“…Objective To examine whether the cardiac, renal and uterine physiological hemodynamic changes during gestation are altered in rats with an early and prolonged…”
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Gender differences in the renal changes induced by a prolonged high-fat diet in rats with altered renal development
Published in Journal of physiology and biochemistry (01-08-2021)“…The mechanisms involved in renal dysfunction induced by high-fat diet (HFD) in subjects with altered renal development (ARDev) are understudied. The objective…”
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Sex-dependent hypertension and renal changes in aged rats with altered renal development
Published in American journal of physiology. Renal physiology (15-08-2014)“…Numerous studies have evaluated blood pressure (BP) and renal changes in several models of developmental programming of hypertension. The present study…”
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Hypertension and Sex Differences in the Age-Related Renal Changes When Cyclooxygenase-2 Activity Is Reduced During Nephrogenesis
Published in Hypertension (Dallas, Tex. 1979) (01-02-2009)“…Several studies have proposed that cyclooxygenase-2 (COX2) is involved in the regulation of nephrogenesis and that an impaired nephrogenesis may induce the…”
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Nitric oxide, prostaglandins and angiotensin II in the regulation of renal medullary blood flow during volume expansion
Published in Journal of physiology and biochemistry (01-03-2016)“…Regulation of medullary blood flow (MBF) is essential in maintaining renal function and blood pressure. However, it is unknown whether outer MBF (OMBF) and…”
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Renal Changes Induced by a Cyclooxygenase-2 Inhibitor During Normal and Low Sodium Intake
Published in Hypertension (Dallas, Tex. 1979) (01-08-2000)“…Cyclooxygenase-2 (COX-2) has been identified in renal tissues under normal conditions, with its expression enhanced during sodium restriction. To evaluate the…”
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SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet
Published in American journal of physiology. Heart and circulatory physiology (01-04-2022)“…Prolonged high-fat diet (HFD) accelerates the cardiovascular, renal, and metabolic dysfunction in hypertensive rats with altered renal development (ARDev)…”
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Cytochrome P-450 Inhibition Attenuates Hypertension Induced by Reductions in Uterine Perfusion Pressure in Pregnant Rats
Published in Hypertension (Dallas, Tex. 1979) (01-03-2004)“…ABSTRACT—The present study tested the hypothesis that cytochrome P-450 (CYP) metabolites of arachidonic acid (AA) are involved in mediating hypertension and…”
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Role of Cyclooxygenase-2 in the Prolonged Regulation of Renal Function
Published in Hypertension (Dallas, Tex. 1979) (01-11-2002)“…ABSTRACT—The role of cyclooxygenase-2 (COX-2) in the prolonged regulation of renal function was evaluated during changes in sodium intake and reduction of NO…”
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Role of nitric oxide and cyclooxygenase-2 in regulating the renal hemodynamic response to norepinephrine
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-02-2003)“…We have reported that the renal hemodynamic effects of norepinephrine (NE) are modulated by cyclooxygenase-2 (COX-2)-derived metabolites. Our main objective…”
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Role of COX-2-derived metabolites in regulation of the renal hemodynamic response to norepinephrine
Published in American journal of physiology. Renal physiology (01-11-2001)“…The objective of this study was to examine the role of cylcooxygenase (COX)-2-derived prostaglandins (PG) in modulating the renal hemodynamic effects of…”
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Role of Nitric Oxide and Prostaglandins in the Long-term Control of Renal Function
Published in Hypertension (Dallas, Tex. 1979) (01-07-1998)“…Previous studies have reported evidence of an important interaction between nitric oxide (NO) and prostaglandins in the acute regulation of renal function. The…”
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Role of Reactive Oxygen Species in Endothelin-Induced Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-10-2003)“…ABSTRACT—Recent reports have indicated that endothelin-induced vasoconstriction in isolated aortic vascular rings may be mediated by the production of…”
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Renal Changes Induced by Nitric Oxide and Prostaglandin Synthesis Reduction: Effects of Trandolapril and Verapamil
Published in Hypertension (Dallas, Tex. 1979) (01-02-1998)“…The benefits of the simultaneous administration of low doses of a calcium antagonist and a converting enzyme inhibitor in the treatment of hypertension and…”
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Changes in NOS activity and protein expression during acute and prolonged ANG II administration
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-01-2002)“…The aim of this study was to assess the effects of acute or prolonged increases of ANG II on nitric oxide synthase (NOS) activities and protein expression in…”
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Effect of Angiotensin II Synthesis Blockade on the Hypertensive Response to Chronic Reductions in Uterine Perfusion Pressure in Pregnant Rats
Published in Hypertension (Dallas, Tex. 1979) (01-09-2001)“…The purpose of this study was to examine the role of the renin-angiotensin system in mediating the hypertension in response to chronic reductions in uterine…”
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Enhanced thromboxane synthesis during chronic reductions in uterine perfusion pressure in pregnant rats
Published in American journal of hypertension (01-09-2002)“…The purpose of this study was to determine the role of thromboxane A 2 (TXA 2) in a conscious, chronically instrumented rat model of pregnancy-induced…”
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Renal effects induced by prolonged mPGES1 inhibition
Published in American journal of physiology. Renal physiology (01-01-2014)“…The importance of membrane-bound PGE synthase 1 (mPGES1) in the regulation of renal function has been examined in mPGES1-deficient mice or by evaluating…”
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Role of cyclooxygenase-2-derived metabolites and NO in renal response to bradykinin
Published in Hypertension (Dallas, Tex. 1979) (2001)“…-It has been reported that bradykinin (BK) can induce or activate both cyclooxygenase (COX) isoforms and that the renal effects of BK seem to be mediated by…”
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