Search Results - "Llewelyn, M J"

A national quality incentive scheme to reduce antibiotic overuse in hospitals: evaluation of perceptions and impact by Islam, J, Ashiru-Oredope, D, Budd, E, Howard, P, Walker, A S, Hopkins, S, Llewelyn, M J

“…Abstract Background In 2016/2017, a financially linked antibiotic prescribing quality improvement initiative Commissioning for Quality and Innovation…”
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Whole genome sequencing in the prevention and control of Staphylococcus aureus infection by Price, J.R, Didelot, X, Crook, D.W, Llewelyn, M.J, Paul, J

“…Summary Background Staphylococcus aureus remains a leading cause of hospital-acquired infection but weaknesses inherent in currently available typing methods…”
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Influence of cohorting patients with Clostridium difficile infection on risk of symptomatic recurrence by Islam, J, Cheek, E, Navani, V, Rajkumar, C, Cohen, J, Llewelyn, M.J

“…Summary Background Cohorting of patients with Clostridium difficile infection (CDI) is recommended when single side-rooms are unavailable. Although patients…”
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Healthcare-associated outbreak of meticillin-resistant Staphylococcus aureus bacteraemia: role of a cryptic variant of an epidemic clone by Miller, R.R, Price, J.R, Batty, E.M, Didelot, X, Wyllie, D, Golubchik, T, Crook, D.W, Paul, J, Peto, T.E.A, Wilson, D.J, Cule, M, Ip, C.L.C, Day, N.P.J, Moore, C.E, Bowden, R, Llewelyn, M.J

“…Summary Background New strains of meticillin-resistant Staphylococcus aureus (MRSA) may be associated with changes in rates of disease or clinical…”
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Prediction of Staphylococcus aureus antimicrobial resistance by whole-genome sequencing by Gordon, N C, Price, J R, Cole, K, Everitt, R, Morgan, M, Finney, J, Kearns, A M, Pichon, B, Young, B, Wilson, D J, Llewelyn, M J, Paul, J, Peto, T E A, Crook, D W, Walker, A S, Golubchik, T

“…Whole-genome sequencing (WGS) could potentially provide a single platform for extracting all the information required to predict an organism's phenotype…”
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The role of the humoral immune response to Clostridium difficile toxins A and B in susceptibility to C. difficile infection: A case–control study by Islam, J., Taylor, A.L., Rao, K., Huffnagle, G., Young, V.B., Rajkumar, C., Cohen, J., Papatheodorou, P., Aronoff, D.M., Llewelyn, M.J.

“…Antibody levels to Clostridium difficile toxin A (TcdA), but not toxin B (TcdB), have been found to determine risk of C. difficile infection (CDI)…”
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The quality of studies evaluating antimicrobial stewardship interventions: a systematic review by Schweitzer, V.A., van Heijl, I., van Werkhoven, C.H., Islam, J., Hendriks-Spoor, K.D., Bielicki, J., Bonten, M.J.M., Walker, A.S., Llewelyn, M.J., Harbarth, S., Huttner, B., Little, P., Rodriguez-Baño, J., Savoldi, A., van Smeden, M., Tacconelli, E., Timsit, J.F., Wolkewitz, M.

“…Antimicrobial stewardship aims to optimize antibiotic use and minimize selection of antimicrobial resistance. The methodological quality of published studies…”
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Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group by Schweitzer, V.A., van Werkhoven, C.H., Rodríguez Baño, J., Bielicki, J., Harbarth, S., Hulscher, M., Huttner, B., Islam, J., Little, P., Pulcini, C., Savoldi, A., Tacconelli, E., Timsit, J.-F., van Smeden, M., Wolkewitz, M., Bonten, M.J.M., Walker, A.S., Llewelyn, M.J.

“…Antimicrobial stewardship interventions and programmes aim to ensure effective treatment while minimizing antimicrobial-associated harms including resistance…”
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Are medical procedures that induce coughing or involve respiratory suctioning associated with increased generation of aerosols and risk of SARS-CoV-2 infection? A rapid systematic review by Wilson, J., Carson, G., Fitzgerald, S., Llewelyn, M.J., Jenkins, D., Parker, S., Boies, A., Thomas, J., Sutcliffe, K., Sowden, A.J., O'Mara-Eves, A., Stansfield, C., Harriss, E., Reilly, J.

“…The risk of transmission of SARS-CoV-2 from aerosols generated by medical procedures is a cause for concern. To evaluate the evidence for aerosol production…”
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Intervention planning for Antibiotic Review Kit (ARK): a digital and behavioural intervention to safely review and reduce antibiotic prescriptions in acute and general medicine by Santillo, M, Sivyer, K, Krusche, A, Mowbray, F, Jones, N, Peto, T E A, Walker, A S, Llewelyn, M J, Yardley, L

“…Abstract Background Hospital antimicrobial stewardship strategies, such as ‘Start Smart, Then Focus’ in the UK, balance the need for prompt, effective…”
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Adaptation and implementation of the ARK (Antibiotic Review Kit) intervention to safely and substantially reduce antibiotic use in hospitals: a feasibility study by Cross, E.L.A., Sivyer, K., Islam, J., Santillo, M., Mowbray, F., Peto, T.E.A., Walker, A.S., Yardley, L., Llewelyn, M.J.

“…Antimicrobial stewardship initiatives in secondary care depend on clinicians undertaking antibiotic prescription reviews but decisions to limit antibiotic…”
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Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition by Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodríguez-Baño, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R., Paterson, D.L.

“…To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI). Prospective studies,…”
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Gram-negative bacteraemia; a multi-centre prospective evaluation of empiric antibiotic therapy and outcome in English acute hospitals by Fitzpatrick, J.M., Biswas, J.S., Edgeworth, J.D., Islam, J., Jenkins, N., Judge, R., Lavery, A.J., Melzer, M., Morris-Jones, S., Nsutebu, E.F., Peters, J., Pillay, D.G., Pink, F., Price, J.R., Scarborough, M., Thwaites, G.E., Tilley, R., Walker, A.S., Llewelyn, M.J., Melzer, Mark, Pink, Frederick, Fitzpatrick, Jennifer, Jones, Gill, Llewelyn, Martin, Peters, Joanna, Biswas, Jason, Edgeworth, Jonathan, Guile, Lucy, Querol-Rubiera, Antonio, Hussain, Abid, Jenkins, Neil, Moran, Ed, Pillay, Devedas, Scarborough, Matthew, Rawlinson, Tom, Judge, Ryan, Tilley, Robert, Lavery, Anita, Morris-Jones, Stephen, Price, James, Nsutebu, Emmanuel

“…Increasing antibiotic resistance makes choosing antibiotics for suspected Gram-negative infection challenging. This study set out to identify key determinants…”
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Diagnostic utility of bone marrow sampling in HIV-infected patients since the advent of highly active antiretroviral therapy by Llewelyn, M J, Noursedeghi, M, Dogan, A, Edwards, S G, Miller, R F

“…We investigated the diagnostic value of bone marrow (BM) sampling in investigation of HIV-infected patients presenting to a major London HIV treatment centre…”
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Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Dissolved Organic Phosphorus Species in a Treatment Wetland after Selective Isolation and Concentration by Llewelyn, Jennifer M, Landing, William M, Marshall, Alan G, Cooper, William T

“…A method for the selective concentration of dissolved organic phosphorus (DOP) from complex surface water samples for the first time allows mass spectral…”
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Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit by Price, James R., Golubchik, Tanya, Cole, Kevin, Wilson, Daniel J., Crook, Derrick W., Thwaites, Guy E., Bowden, Rory, Walker, A. Sarah, Peto, Timothy E. A., Paul, John, Llewelyn, Martin J.

“…Background. Strategies to prevent Staphylococcus aureus infection in hospitals focus on patient-to-patient transmission. We used whole-genome sequencing to…”
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The State of Hospital Infection Services in the UK: National Workforce Survey 2021 by Lawrence, S., Aggarwal, D., Davies, A., Partridge, D., Ratnaraja, N., Llewelyn, M.J.

“…Introduction: With the evolution of centralised ‘hub and spoke’ microbiology services, the expansion of infectious diseases as a medical specialty and the…”
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Tracking the Microbes in Sepsis: Advancements in Treatment Bring Challenges for Microbial Epidemiology by Llewelyn, Martin J., Cohen, Jonathan

“…During the 1980s and 1990s, sepsis research propelled dozens of potential therapeutic candidates into clinical trials without a single novel therapeutic…”
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Reply to Mills and Linkin by Price, James R., Golubchik, Tanya, Wilson, Daniel J., Crook, Derrick W., Walker, A. Sarah, Peto, Timothy E. A., Paul, John, Llewelyn, Martin J.

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Predictors of Death after Clostridium difficile Infection: A Report on 128 Strain-Typed Cases from a Teaching Hospital in the United Kingdom by Wilson, Vhairi, Cheek, Liz, Satta, Giovanni, Bone, Karen Walker, Cubbon, Marc, Citron, Diane, Gerding, Dale N., Llewelyn, Martin J.

“…We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not…”
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