Search Results - "Lletí, Esther Roselló"

Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats by Aragón-Herrera, Alana, Feijóo-Bandín, Sandra, Otero Santiago, Manuel, Barral, Luis, Campos-Toimil, Manuel, Gil-Longo, José, Costa Pereira, Thiago M., García-Caballero, Tomás, Rodríguez-Segade, Santiago, Rodríguez, Javier, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Gualillo, Oreste, González-Juanatey, José Ramón, Lago, Francisca

“…[Display omitted] The EMPA-REG OUTCOME (Empagliflozin, Cardiovascular Outcome Event Trial in patients with Type 2 Diabetes Mellitus (T2DM)) trial made evident…”
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Adipokines and Inflammation: Focus on Cardiovascular Diseases by Feijóo-Bandín, Sandra, Aragón-Herrera, Alana, Moraña-Fernández, Sandra, Anido-Varela, Laura, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Moscoso, Isabel, Gualillo, Oreste, González-Juanatey, José Ramón, Lago, Francisca

“…It is well established that adipose tissue, apart from its energy storage function, acts as an endocrine organ that produces and secretes a number of bioactive…”
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Endolysosomal two‐pore channels regulate autophagy in cardiomyocytes by García‐Rúa, Vanessa, Feijóo‐Bandín, Sandra, Rodríguez‐Penas, Diego, Mosquera‐Leal, Ana, Abu‐Assi, Emad, Beiras, Andrés, María Seoane, Luisa, Lear, Pamela, Parrington, John, Portolés, Manuel, Roselló‐Lletí, Esther, Rivera, Miguel, Gualillo, Oreste, Parra, Valentina, Hill, Joseph A., Rothermel, Beverly, González‐Juanatey, José Ramón, Lago, Francisca

“…Key points Two‐pore channels (TPCs) were identified as a novel family of endolysosome‐targeted calcium release channels gated by nicotinic acid adenine…”
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Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models by Feijóo-Bandín, Sandra, Aragón-Herrera, Alana, Otero-Santiago, Manuel, Anido-Varela, Laura, Moraña-Fernández, Sandra, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Gualillo, Oreste, González-Juanatey, José Ramón, Lago, Francisca

“…Sodium-glucose co-transporter 2 inhibitors, also known as gliflozins, were developed as a novel class of anti-diabetic agents that promote glycosuria through…”
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Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex by Tarazón, Estefanía, Pérez‐Carrillo, Lorena, García‐Bolufer, Pau, Triviño, Juan C., Feijóo‐Bandín, Sandra, Lago, Francisca, González‐Juanatey, José R., Martínez‐Dolz, Luis, Portolés, Manuel, Roselló‐Lletí, Esther

“…Acute rejection after heart transplantation increases the risk of chronic dysfunction. Disturbances in mitochondrial function may play a contributory role,…”
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Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors by Giménez-Escamilla, Isaac, Pérez-Carrillo, Lorena, González-Torrent, Irene, Delgado-Arija, Marta, Benedicto, Carlota, Portolés, Manuel, Tarazón, Estefanía, Roselló-Lletí, Esther

“…Heart failure (HF) is associated with global changes in gene expression. Alternative mRNA splicing (AS) is a key regulatory mechanism underlying these changes…”
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Relaxin has beneficial effects on liver lipidome and metabolic enzymes by Aragón‐Herrera, Alana, Feijóo‐Bandín, Sandra, Moraña‐Fernández, Sandra, Anido‐Varela, Laura, Roselló‐Lletí, Esther, Portolés, Manuel, Tarazón, Estefanía, Lage, Ricardo, Moscoso, Isabel, Barral, Luis, Bani, Daniele, Bigazzi, Mario, Gualillo, Oreste, González‐Juanatey, José Ramón, Lago, Francisca

“…Relaxin is an insulin‐like hormone with pleiotropic protective effects in several organs, including the liver. We aimed to characterize its role in the control…”
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Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation by Delgado-Arija, Marta, Genovés, Patricia, Pérez-Carrillo, Lorena, González-Torrent, Irene, Giménez-Escamilla, Isaac, Martínez-Dolz, Luis, Portolés, Manuel, Tarazón, Estefanía, Roselló-Lletí, Esther

“…Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions…”
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The altered expression of autophagy-related genes participates in heart failure: NRBP2 and CALCOCO2 are associated with left ventricular dysfunction parameters in human dilated cardiomyopathy by Gil-Cayuela, Carolina, López, Alejandro, Martínez-Dolz, Luis, González-Juanatey, José Ramón, Lago, Francisca, Roselló-Lletí, Esther, Rivera, Miguel, Portolés, Manuel

“…This study aimed to analyze changes in the expression of autophagy- and phagocytosis-related genes in patients with dilated cardiomyopathy (DCM), especially in…”
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Relaxin-2 plasma levels in atrial fibrillation are linked to inflammation and oxidative stress markers by Aragón-Herrera, Alana, Couselo-Seijas, Marinela, Feijóo-Bandín, Sandra, Anido-Varela, Laura, Moraña-Fernández, Sandra, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Martínez-Sande, José Luis, García-Seara, Javier, Álvarez, Ezequiel, González-Juanatey, José Ramón, Rodríguez-Mañero, Moisés, Eiras, Sonia, Lago, Francisca

“…Relaxin-2 exerts many favourable cardiovascular effects in pathological circumstances such as atrial fibrillation (AF) and heart failure, but the mechanisms…”
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Plasma CD5L and non-invasive diagnosis of acute heart rejection by Tarazón, Estefanía, Corbacho-Alonso, Nerea, Barderas, María G., Gil-Cayuela, Carolina, García-Manzanares, María, Feijóo-Bandín, Sandra, Lago, Francisca, González-Juanatey, José Ramón, Martínez-Dolz, Luis, Portolés, Manuel, Roselló-Lletí, Esther

“…Acute rejection is one of the most important direct contributors to mortality after heart transplantation. Advances in the development of novel non-invasive…”
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Endoplasmic reticulum stress induces different molecular structural alterations in human dilated and ischemic cardiomyopathy by Ortega, Ana, Roselló-Lletí, Esther, Tarazón, Estefanía, Molina-Navarro, Maria Micaela, Martínez-Dolz, Luis, González-Juanatey, José Ramón, Lago, Francisca, Montoro-Mateos, Jose David, Salvador, Antonio, Rivera, Miguel, Portolés, Manuel

“…The endoplasmic reticulum (ER) is a multifunctional organelle responsible for the synthesis and folding of proteins as well as for signalling and calcium…”
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Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection by Tarazón, Estefanía, Gil-Cayuela, Carolina, Manzanares, María García, Roca, Marta, Lago, Francisca, González-Juanatey, José Ramón, Sánchez-Lacuesta, Elena, Martínez-Dolz, Luis, Portolés, Manuel, Roselló-Lletí, Esther

“…Accumulating evidence has confirmed that the expression of sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) is downregulated in heart failure and cardiac…”
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Myocardium of patients with dilated cardiomyopathy presents altered expression of genes involved in thyroid hormone biosynthesis by Gil-Cayuela, Carolina, Ortega, Ana, Tarazón, Estefanía, Martínez-Dolz, Luis, Cinca, Juan, González-Juanatey, José Ramón, Lago, Francisca, Roselló-Lletí, Esther, Rivera, Miguel, Portolés, Manuel

“…The association between dilated cardiomyopathy (DCM) and low thyroid hormone (TH) levels has been previously described. In these patients abnormal thyroid…”
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Differential gene expression of cardiac ion channels in human dilated cardiomyopathy by Molina-Navarro, Maria Micaela, Roselló-Lletí, Esther, Ortega, Ana, Tarazón, Estefanía, Otero, Manuel, Martínez-Dolz, Luis, Lago, Francisca, González-Juanatey, José Ramón, España, Francisco, García-Pavía, Pablo, Montero, José Anastasio, Portolés, Manuel, Rivera, Miguel

“…Dilated cardiomyopathy (DCM) is characterized by idiopathic dilation and systolic contractile dysfunction of the cardiac chambers. The present work aimed to…”
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New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. PCDHGA3 Implications in Decreased Stroke Volume and Ventricular Dysfunction by Ortega, Ana, Gil-Cayuela, Carolina, Tarazón, Estefanía, García-Manzanares, María, Montero, José Anastasio, Cinca, Juan, Portolés, Manuel, Rivera, Miguel, Roselló-Lletí, Esther

“…Intercalated disks are unique structures in cardiac tissue, in which adherens junctions, desmosomes, and GAP junctions co-localize, thereby facilitating…”
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Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function by Ortega, Ana, Tarazón, Estefanía, Gil-Cayuela, Carolina, García-Manzanares, María, Martínez-Dolz, Luis, Lago, Francisca, González-Juanatey, José Ramón, Cinca, Juan, Jorge, Esther, Portolés, Manuel, Roselló-Lletí, Esther, Rivera, Miguel

“…Alterations in myocardial structure and reduced cardiomyocyte adhesions have been previously described in dilated cardiomyopathy (DCM). We studied the…”
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RNA-sequencing analysis reveals new alterations in cardiomyocyte cytoskeletal genes in patients with heart failure by Herrer, Isabel, Roselló-Lletí, Esther, Rivera, Miguel, Molina-Navarro, María Micaela, Tarazón, Estefanía, Ortega, Ana, Martínez-Dolz, Luis, Triviño, Juan Carlos, Lago, Francisca, González-Juanatey, José R, Bertomeu, Vicente, Montero, José Anastasio, Portolés, Manuel

“…Changes in cardiomyocyte cytoskeletal components, a crucial scaffold of cellular structure, have been found in heart failure (HF); however, the altered…”
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Cardiac Sodium/Hydrogen Exchanger (NHE11) as a Novel Potential Target for SGLT2i in Heart Failure: A Preliminary Study by Pérez-Carrillo, Lorena, Aragón-Herrera, Alana, Giménez-Escamilla, Isaac, Delgado-Arija, Marta, García-Manzanares, María, Anido-Varela, Laura, Lago, Francisca, Martínez-Dolz, Luis, Portolés, Manuel, Tarazón, Estefanía, Roselló-Lletí, Esther

“…Despite the reduction of cardiovascular events, including the risk of death, associated with sodium/glucose cotransporter 2 inhibitors (SGLT2i), their basic…”
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The Treatment With the SGLT2 Inhibitor Empagliflozin Modifies the Hepatic Metabolome of Male Zucker Diabetic Fatty Rats Towards a Protective Profile by Aragón-Herrera, Alana, Otero-Santiago, Manuel, Anido-Varela, Laura, Moraña-Fernández, Sandra, Campos-Toimil, Manuel, García-Caballero, Tomás, Barral, Luis, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Gualillo, Oreste, Moscoso, Isabel, Lage, Ricardo, González-Juanatey, José Ramón, Feijóo-Bandín, Sandra, Lago, Francisca

“…The EMPA-REG OUTCOME (Empagliflozin, Cardiovascular Outcome Event Trial in patients with Type 2 Diabetes Mellitus (T2DM)) trial evidenced the potential of…”
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