Search Results - "Llergo, José L."
-
1
High glucose induces cell death of cultured human aortic smooth muscle cells through the formation of hydrogen peroxide
Published in British journal of pharmacology (01-08-2001)“…Alterations of the vessel structure, which is mainly determined by smooth muscle cells through cell growth and/or cell death mechanisms, are characteristic of…”
Get full text
Journal Article -
2
P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action
Published in PloS one (23-02-2012)“…Chemotherapy is still the cornerstone for malaria control. Developing drugs against Plasmodium parasites and monitoring their efficacy requires methods to…”
Get full text
Journal Article -
3
Endothelial dysfunction and metabolic control in streptozotocin‐induced diabetic rats
Published in British journal of pharmacology (01-04-1998)“…The aim of this work was to study the influence of the metabolic control, estimated by the levels of glycosylated haemoglobin in total blood samples (HbA1c),…”
Get full text
Journal Article -
4
Prevention of endothelial dysfunction in streptozotocin-induced diabetic rats by gliclazide treatment
Published in Journal of diabetes and its complications (01-07-2000)“…The aim of the present work was to analyze whether the oral hypoglycemic drug gliclazide affects diabetic endothelial dysfunction in streptozotocin-induced…”
Get full text
Journal Article Conference Proceeding -
5
Vascular smooth muscle cell hypertrophy induced by glycosylated human oxyhaemoglobin
Published in British journal of pharmacology (01-10-1998)“…1 Nonenzymatic protein glycosylation is a possible mechanism contributing to oxidative stress and vascular disease in diabetes. In this work, the influence of…”
Get full text
Journal Article -
6
Pharmacological interference of vascular smooth muscle cell hypertrophy induced by glycosylated human oxyhaemoglobin
Published in European journal of pharmacology (15-12-1999)“…Nonenzymatically glycosylated human oxyhaemoglobin induces vascular smooth muscle cell hypertrophy by releasing reactive oxygen species. We analysed the…”
Get full text
Journal Article -
7
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren‐2 transgenic rats
Published in British journal of pharmacology (01-08-1997)“…We hypothesized that tissular renin‐angotensin system (RAS) induces vascular hypertrophy in hypertensive Ren‐2 transgenic rats (TGR; strain name…”
Get full text
Journal Article -
8
Nifedipine, losartan and captopril effects on hyperplasia of vascular smooth muscle from Ren-2 transgenic rats
Published in European journal of pharmacology (18-04-1997)“…Vascular smooth muscle cells from hypertensive transgenic rats for the mouse Ren-2 gene exhibited radioimmunoassayable angiotensin II and hyperplasia in…”
Get full text
Journal Article -
9
Enhancement of S-Nitrosylation in Glycosylated Hemoglobin
Published in Biochemical and biophysical research communications (29-04-2000)“…In this study, we report a novel differential nitric oxide interaction with nonglycosylated and glycosylated hemoglobin. After in vitro incubation of…”
Get full text
Journal Article -
10
Treatment with Acarbose May Improve Endothelial Dysfunction in Streptozotocin-Induced Diabetic Rats
Published in Journal of cardiovascular pharmacology (01-08-2000)“…We sought to determine whether a single reduction of hyperglycemia and those derivatives from nonenzymatic protein glycosylation may be effective in reducing…”
Get full text
Journal Article