Thromboelastometry-guided surgery in neuroblastoma complicated with disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC) is a rare oncological emergency. We report a pediatric neuroblastoma complicated with DIC which required thromboelastometry-guided surgery. A 6-year-old female diagnosed with intermediate risk adrenal neuroblastoma developed tumor-related DIC after chemot...

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Bibliographic Details
Published in:	Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Vol. 36; no. 1; p. 44
Main Authors:	Pérez-Torres Lobato, M R, Molina Mata, M, Llempen López, M L, Fernández-Pineda, I, Cabello Laureano, R M, Rodríguez Martorell, J
Format:	Journal Article
Language:	English
Published:	Spain 01-01-2023
Subjects:	Child Disseminated Intravascular Coagulation - complications Female Humans Neuroblastoma - complications Neuroblastoma - surgery Thrombelastography - adverse effects Rotational thromboelastometry Disseminated intravascular coagulation Children Neuroblastoma Cancer
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Summary:	Disseminated intravascular coagulation (DIC) is a rare oncological emergency. We report a pediatric neuroblastoma complicated with DIC which required thromboelastometry-guided surgery. A 6-year-old female diagnosed with intermediate risk adrenal neuroblastoma developed tumor-related DIC after chemotherapy first cycle. She remained stable without clinical bleeding and emergent tumor resection guided by intraoperative-thromboelastometry was decided. DIC resolved early after surgery and complete remission was achieved. Treatment of the underlying condition is critical to manage DIC. Thromboelastometry can guide goal-directed therapy, including surgery in pediatric patients. However, larger studies are needed to examine its applicability in different clinical settings, such as cancer related DIC.
ISSN:	2445-2807