Search Results - "Llano, Daniel"

Does hearing loss lead to dementia? A review of the literature by Nadhimi, Yosra, Llano, Daniel A.

“…Recent studies have revealed a correlation between aging-related hearing loss and the likelihood of developing Alzheimer Disease. However, it is not yet known…”
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Serum Phosphatidylethanolamine and Lysophosphatidylethanolamine Levels Differentiate Alzheimer's Disease from Controls and Predict Progression from Mild Cognitive Impairment by Llano, Daniel A, Devanarayan, Viswanath

“…There is intense interest in the development of blood-based biomarkers, not only that can differentiate Alzheimer's disease (AD) from controls, but that can…”
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CSF peptides from VGF and other markers enhance prediction of MCI to AD progression using the ATN framework by Llano, Daniel A., Devanarayan, Priya, Devanarayan, Viswanath

“…The amyloid beta, tau, neurodegenerative markers framework has been proposed to serve as a system to classify and combine biomarkers for Alzheimer's Disease…”
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Functional imaging of the thalamus in language by Llano, Daniel A.

“…► 50 studies demonstrating thalamic activation during language tasks were reviewed. ► Thalamic activation was seen in tasks requiring lexical information…”
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Top-Down Inference in the Auditory System: Potential Roles for Corticofugal Projections by Asilador, Alexander, Llano, Daniel A

“…It has become widely accepted that humans use contextual information to infer the meaning of ambiguous acoustic signals. In speech, for example, high-level…”
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Auditory thalamic circuits and GABAA receptor function: Putative mechanisms in tinnitus pathology by Caspary, Donald M., Llano, Daniel A.

“…Tinnitus is defined as a phantom sound (ringing in the ears), and can significantly reduce the quality of life for those who suffer its effects. Ten to fifteen…”
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VGF in Cerebrospinal Fluid Combined With Conventional Biomarkers Enhances Prediction of Conversion From MCI to AD by Llano, Daniel A, Devanarayan, Priya, Devanarayan, Viswanath

“…BACKGROUND:Previous work has suggested that the brain and cerebrospinal fluid (CSF) levels of a neural protein involved in synaptic transmission, VGF (a…”
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Descending projections to the auditory midbrain: evolutionary considerations by Macias, Silvio, Llano, Daniel A.

“…The mammalian inferior colliculus (IC) is massively innervated by multiple descending projection systems. In addition to a large projection from the auditory…”
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Auditory thalamic circuits and GABA A receptor function: Putative mechanisms in tinnitus pathology by Caspary, Donald M, Llano, Daniel A

“…Tinnitus is defined as a phantom sound (ringing in the ears), and can significantly reduce the quality of life for those who suffer its effects. Ten to fifteen…”
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Aging-related cerebral microvascular changes visualized using ultrasound localization microscopy in the living mouse by Lowerison, Matthew R., Sekaran, Nathiya Vaithiyalingam Chandra, Zhang, Wei, Dong, Zhijie, Chen, Xi, Llano, Daniel A., Song, Pengfei

“…Aging-related cognitive decline is an emerging health crisis; however, no established unifying mechanism has been identified for the cognitive impairments seen…”
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The corticothalamocortical circuit drives higher-order cortex in the mouse by Theyel, Brian B, Llano, Daniel A, Sherman, S Murray

“…Information flow in the cortex is usually thought to be subserved by direct, cortico-cortical connections. Using optical imaging in a thalmocortical slice…”
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A multivariate predictive modeling approach reveals a novel CSF peptide signature for both Alzheimer's Disease state classification and for predicting future disease progression by Llano, Daniel A, Bundela, Saurabh, Mudar, Raksha A, Devanarayan, Viswanath

“…To determine if a multi-analyte cerebrospinal fluid (CSF) peptide signature can be used to differentiate Alzheimer's Disease (AD) and normal aged controls…”
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Role of auditory-somatosensory corticothalamic circuit integration in analgesia by Brunelle, Dimitri L., Llano, Daniel A.

“…•Sound and tactile information interact at several levels of the nervous system.•Zhou et al. in July 2022 demonstrated a novel corticothalamic multisensory…”
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Super-Resolution Ultrasound Reveals Cerebrovascular Impairment in a Mouse Model of Alzheimer's Disease by Lowerison, Matthew R, Vaithiyalingam Chandra Sekaran, Nathiya, Dong, Zhijie, Chen, Xi, You, Qi, Llano, Daniel A, Song, Pengfei

“…Increasing evidence has suggested a link between cerebrovascular disease and the cognitive impairment associated with Alzheimer's disease. However, detailed…”
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Hitting The Right Spot: NMDA Receptors in the Auditory Thalamus May Hold the Key to Understanding Schizophrenia by Xiao, Gang, Llano, Daniel A

“…Abstract In this issue, Wang and colleagues solve an important puzzle in the understanding of schizophrenia. Previous work has linked N-methyl-D-aspartate…”
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Auditory system dysfunction in Alzheimer disease and its prodromal states: A review by Swords, Gabriel M, Nguyen, Lydia T, Mudar, Raksha A, Llano, Daniel A

“…Recent findings suggest that both peripheral and central auditory system dysfunction occur in the prodromal stages of Alzheimer Disease (AD), and therefore may…”
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Localization free super-resolution microbubble velocimetry using a long short-term memory neural network by Chen, Xi, Lowerison, Matthew R., Dong, Zhijie, Sekaran, Nathiya Vaithiyalingam Chandra, Llano, Daniel A., Song, Pengfei

“…Ultrasound localization microscopy is a super-resolution imaging technique that exploits the unique characteristics of contrast microbubbles to side-step the…”
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Diminished cortical inhibition in an aging mouse model of chronic tinnitus by Llano, Daniel A, Turner, Jeremy, Caspary, Donald M

“…Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic responses in aged animals with behavioral evidence of tinnitus and hearing…”
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Connectional Modularity of Top-Down and Bottom-Up Multimodal Inputs to the Lateral Cortex of the Mouse Inferior Colliculus by Lesicko, Alexandria M H, Hristova, Teodora S, Maigler, Kathleen C, Llano, Daniel A

“…The lateral cortex of the inferior colliculus receives information from both auditory and somatosensory structures and is thought to play a role in…”
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Voluntary wheel running has no impact on brain and liver mitochondrial DNA copy number or mutation measures in the PolG mouse model of aging by Maclaine, Kendra D, Stebbings, Kevin A, Llano, Daniel A, Rhodes, Justin S

“…The mitochondrial theory of aging attributes much of the aging process to mitochondrial DNA damage. The polymerase gamma (PolG) mutant mouse was designed to…”
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