Search Results - "Llames, Sara"
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1
Natural Occurrence of Autoantibodies against Basement Membrane Proteins in Epidermolysis Bullosa
Published in Journal of investigative dermatology (01-07-2022)Get full text
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2
Polymerizable Skin Hydrogel for Full Thickness Wound Healing
Published in International journal of molecular sciences (27-04-2022)“…The skin is the largest organ in the human body, comprising the main barrier against the environment. When the skin loses its integrity, it is critical to…”
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3
Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells
Published in Molecular therapy. Nucleic acids (01-06-2018)“…Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII collagen at the dermal-epidermal junction…”
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4
Driving role of head and neck cancer cell secretome on the invasion of stromal fibroblasts: Mechanistic insights by phosphoproteomics
Published in Biomedicine & pharmacotherapy (01-02-2023)“…Cancer-associated fibroblasts (CAFs) are major players in tumor-stroma communication, and participate in several cancer hallmarks to drive tumor progression…”
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5
In-stent restenosis is associated with proliferative skin healing and specific immune and endothelial cell profiles: results from the RACHEL trial
Published in Frontiers in immunology (31-05-2023)“…In-stent restenosis (ISR) is a major challenge in interventional cardiology. Both ISR and excessive skin healing are aberrant hyperplasic responses, which may…”
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6
Unveiling the value of C‐reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross‐sectional study
Published in Experimental dermatology (01-08-2024)“…Patients with recessive dystrophic epidermolysis bullosa (RDEB) experience numerous complications, which are exacerbated by inflammatory dysregulation and…”
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Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy
Published in Biosensors (Basel) (20-01-2023)“…The rabbit skin irritation test has been the standard for evaluating the irritation potential of chemicals; however, alternative methods that do not use animal…”
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Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome
Published in Molecular therapy. Methods & clinical development (11-09-2020)“…Current efforts to find specific genodermatoses treatments and define precise pathogenesis mechanisms require appropriate surrogate models with human cells…”
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Ectopic bone formation during tissue-engineered cartilage repair using autologous chondrocytes and novel plasma-derived albumin scaffolds
Published in Journal of cranio-maxillo-facial surgery (01-10-2016)“…Summary Purpose The aims of this study were twofold: first, to evaluate the production of cartilaginous tissue in vitro and in vivo using a novel…”
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10
Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy
Published in Journal of investigative dermatology (01-02-2014)Get full text
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Tissue-Engineered Oral Mucosa Grafts for Intraoral Lining Reconstruction of the Maxilla and Mandible With a Fibula Flap
Published in Journal of oral and maxillofacial surgery (2015)“…Purpose Many types of soft tissue grafts have been used for grafting or prelaminating bone flaps for intraoral lining reconstruction. The best results are…”
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12
Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin
Published in Transplantation (15-02-2004)“…Keratinocyte cultures have been used for the treatment of severe burn patients. Here, we describe a new cultured bioengineered skin based on (1) keratinocytes…”
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13
DNA Repair and Immune Response Pathways Are Deregulated in Melanocyte-Keratinocyte Co-cultures Derived From the Healthy Skin of Familial Melanoma Patients
Published in Frontiers in medicine (01-10-2021)“…Familial melanoma accounts for 10% of cases, being CDKN2A the main high-risk gene. However, the mechanisms underlying melanomagenesis in these cases remain…”
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14
Keratinocyte cell lines derived from severe generalized recessive Epidermolysis Bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo
Published in Experimental dermatology (01-09-2013)“…Recessive dystrophic epidermolysis bullosa (RDEB) is caused by deficiency of type VII collagen due to COL7A1 mutations such as c.6527insC, recurrently found in…”
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15
Abstract: Autologous Engineered Skin for Coverage after Giant Congenital Melanocytic Nevi Resection
Published in Plastic and reconstructive surgery. Global open (01-09-2018)Get full text
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16
Clinical outcomes after the use of complete autologous oral mucosa equivalents: preliminary cases
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-05-2012)“…Objective Previously, we reported how to obtain complete autologous oral mucosa equivalents (CAOMEs) composed of an autologous plasma scaffold and fibroblasts…”
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17
Feeder Layer Cell Actions and Applications
Published in Tissue engineering. Part B, Reviews (01-08-2015)“…Cultures of growth-arrested feeder cells have been used for years to promote cell proliferation, particularly with low-density inocula. Basically, feeder cells…”
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TCT-140 Relationship Between In-Stent Restenosis, Excessive Skin Healing, and Patient’s Immunologic Profile
Published in Journal of the American College of Cardiology (01-09-2022)Get full text
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19
Development of an in-house reconstructed human epidermis model as an alternative method in skin corrosion assessment
Published in Toxicology in vitro (01-06-2020)“…Defining the corrosive properties of chemical products generally involves the use of animal models for human health safety assessment. However, a few…”
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Human plasma gels: Their preparation and rheological characterization for cell culture applications in tissue engineering
Published in Journal of the mechanical behavior of biomedical materials (01-01-2019)“…Tissue engineering is one of the fields of clinical medicine that has forged ahead in recent years, especially because of its role as a potential alternative…”
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