Search Results - "Llamazares Prada, Maria"
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High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
Published in The EMBO journal (15-06-2023)“…Patients with chronic obstructive pulmonary disease (COPD) are still waiting for curative treatments. Considering its environmental cause, we hypothesized that…”
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2
HDAC6 score: to treat or not to treat?
Published in Nature cancer (01-02-2023)Get full text
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Human Desmocollin 3‒Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus
Published in Journal of investigative dermatology (01-03-2022)“…Pemphigus is a potentially lethal autoimmune bullous skin disorder, which is associated with IgG autoantibodies against desmoglein (DSG) 3 and DSG1. Notably, a…”
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MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis
Published in Nature cancer (01-04-2022)“…Aberrant expression of MYC transcription factor family members predicts poor clinical outcome in many human cancers. Oncogenic MYC profoundly alters metabolism…”
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Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung
Published in JCI insight (22-03-2021)“…Complexity of lung microenvironment and changes in cellular composition during disease make it exceptionally hard to understand molecular mechanisms driving…”
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Practical Considerations for Complex Tissue Dissociation for Single-Cell Transcriptomics
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Single-cell and single-nucleus RNA sequencing have revolutionized biomedical research, allowing analysis of complex tissues, identification of novel cell…”
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UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis
Published in Cancer research (Chicago, Ill.) (01-04-2020)“…For maximal oncogenic activity, cellular MYC protein levels need to be tightly controlled so that they do not induce apoptosis. Here, we show how ubiquitin…”
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