Search Results - "Llamas, Josué"
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TDP‐43 and tau concurrence in the entorhinal subfields in primary age‐related tauopathy and preclinical Alzheimer's disease
Published in Brain pathology (Zurich, Switzerland) (01-07-2023)“…Phosphorylated tau (p‐tau) pathology correlates strongly with cognitive decline and is a pathological hallmark of Alzheimer's Disease (AD). In recent years,…”
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Pentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus
Published in Frontiers in neuroanatomy (09-02-2023)“…The hippocampus is integral for learning and memory and is targeted by multiple diseases. Neuroimaging approaches frequently use hippocampal subfield volumes…”
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Assessing individual variability of the entorhinal subfields in health and disease
Published in Journal of comparative neurology (1911) (01-12-2023)“…Investigating interindividual variability is a major field of interest in neuroscience. The entorhinal cortex (EC) is essential for memory and affected early…”
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Learning impairments and molecular changes in the brain caused by β-catenin loss
Published in Human molecular genetics (01-09-2019)“…Abstract Intellectual disability (ID), defined as IQ<70, occurs in 2.5% of individuals. Elucidating the underlying molecular mechanisms is essential for…”
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Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions
Published in Scientific reports (11-04-2023)“…Hippocampal subregions differ in specialization and vulnerability to cell death. Neuron death and hippocampal atrophy have been a marker for the progression of…”
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The Six-Transmembrane Enzyme GDE2 Is Required for the Release of Molecularly Distinct Small Extracellular Vesicles from Neurons
Published in Cells (Basel, Switzerland) (24-08-2024)“…Extracellular vesicles (EVs) are implicated in a multitude of physiological and pathophysiological processes in the nervous system; however, their biogenesis…”
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Quantitative and histologically validated measures of the entorhinal subfields in ex vivo MRI
Published in Brain communications (02-05-2022)“…Abstract Neuroimaging studies have routinely used hippocampal volume as a measure of Alzheimer’s disease severity, but hippocampal changes occur too late in…”
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Entorhinal vessel density correlates with phosphorylated tau and TDP‐43 pathology
Published in Alzheimer's & dementia (01-07-2024)“…INTRODUCTION The entorhinal cortex (EC) and perirhinal cortex (PC) are vulnerable to Alzheimer's disease. A triggering factor may be the interaction of…”
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Entorhinal Subfield Vulnerability to Neurofibrillary Tangles in Aging and the Preclinical Stage of Alzheimer's Disease
Published in Journal of Alzheimer's disease (2022)“…Neurofibrillary tangle (NFT) accumulation in the entorhinal cortex (EC) precedes the transformation from cognitive controls to mild cognitive impairment and…”
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Neuron collinearity differentiates human hippocampal subregions: a validated deep learning approach
Published in Brain communications (2024)“…Abstract The hippocampus is heterogeneous in its architecture. It contributes to cognitive processes such as memory and spatial navigation and is susceptible…”
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