Search Results - "Llacuna, L"

PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors by Farrés, J, Llacuna, L, Martin-Caballero, J, Martínez, C, Lozano, J J, Ampurdanés, C, López-Contreras, A J, Florensa, L, Navarro, J, Ottina, E, Dantzer, F, Schreiber, V, Villunger, A, Fernández-Capetillo, O, Yélamos, J

“…Erythropoiesis is a tightly regulated process in which multipotential hematopoietic stem cells produce mature red blood cells. Here we show that deletion of…”
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Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo by MORALES, A, PARIS, R, VILLANUEVA, A, LLACUNA, L, GARCIA-RUIZ, C, FERNANDEZ-CHECA, J. C

“…Ceramidases (CDases) play a key role in cancer therapy through enhanced conversion of ceramide into sphingosine 1-phosphate (S1P), but their involvement in…”
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Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage by Bock, F J, Krumschnabel, G, Manzl, C, Peintner, L, Tanzer, M C, Hermann-Kleiter, N, Baier, G, Llacuna, L, Yelamos, J, Villunger, A

“…Activation of NF- κ B (nuclear factor of kappa light chain gene enhancer in B cells) in response to DNA damage is considered to contribute to repair of genetic…”
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160 SELECTIVE ACTIVATION OF PROTECTIVE NF-KB DEPENDENT GENES BY S-ADENOSYLMETHIONINE REDUCES ISCHEMIA/REPERFUSION INJURY IN MOUSE LIVER by Llacuna, L, Morales, A, Fernandez-Checa, J.C

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138 CRITICAL ROLE OF CHOLESTEROL IN THE SENSITIZATION OF STEATOTIC LIVER TO ISCHEMIA/REPERFUSION INJURY by Llacuna, L, Morales, A, Fernandez, A, Fernandez-Checa, J.C, Garcia-Ruiz, C

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159 GAS6 PROTECTS AGAINST HEPATIC ISCHEMIA/REPERFUSION INJURY THROUGH AKT ACTIVATION by Llacuna, L, Bellido, D, Garcia de Frutos, P, Fernandez-Checa, J.C, Morales, A

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426 INHIBITION OF THE SQUALENE SYNTHASE OR STAR SILENCING INCREASES THE SUSCEPTIBILITY OF HEPATOCELLULAR CARCINOMA TO CHEMOTHERAPY by Montero, J, Morales, A, Llacuna, L, Lluis, J.M, Garcia-Ruiz, C, Colell, A, Fernandez-Checa, J.C

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Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3‑b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors by Liscio, Paride, Carotti, Andrea, Asciutti, Stefania, Karlberg, Tobias, Bellocchi, Daniele, Llacuna, Laura, Macchiarulo, Antonio, Aaronson, Stuart A, Schüler, Herwig, Pellicciari, Roberto, Camaioni, Emidio

“…Searching for selective tankyrases (TNKSs) inhibitors, a new small series of 6,8-disubstituted triazolo[4,3-b]piridazines has been synthesized and…”
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Loss of PIDD limits NF-[kappa]B activation and cytokine production but not cell survival or transformation after DNA damage by Bock, F J, Krumschnabel, G, Manzl, C, Peintner, L, Tanzer, M C, Hermann-kleiter, N, Baier, G, Llacuna, L, Yelamos, J, Villunger, A

“…Activation of NF-κB (nuclear factor of kappa light chain gene enhancer in B cells) in response to DNA damage is considered to contribute to repair of genetic…”
Get full text

Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo by Morales, A, Paris, R, Villanueva, A, Llacuna, L, Garcia-Ruiz, C, Fernandez-Checa, J C

“…Ceramidases (CDases) play a key role in cancer therapy through enhanced conversion of ceramide into sphingosine 1-phosphate (S1P), but their involvement in…”
Get full text