Search Results - "Llácer, Jose Luis"
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Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition
Published in eLife (30-11-2018)“…In eukaryotic translation initiation, AUG recognition of the mRNA requires accommodation of Met-tRNA in a 'P ' state, which is antagonized by the factor eIF1…”
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2
Structural basis for the inhibition of translation through eIF2α phosphorylation
Published in Nature communications (14-06-2019)“…One of the responses to stress by eukaryotic cells is the down-regulation of protein synthesis by phosphorylation of translation initiation factor eIF2…”
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3
The PII-NAGK-PipX-NtcA Regulatory Axis of Cyanobacteria: A Tale of Changing Partners, Allosteric Effectors and Non-covalent Interactions
Published in Frontiers in molecular biosciences (13-11-2018)“…P II , a homotrimeric very ancient and highly widespread (bacteria, archaea, plants) key sensor-transducer protein, conveys signals of abundance or poorness of…”
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4
The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high‐salt adaptations
Published in The FEBS journal (01-08-2014)“…To obtain insights into archaeal nitrogen signaling and haloadaptation of the nitrogen/carbon/energy‐signaling protein PII, we determined crystal structures of…”
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5
Determination of metabolite concentrations in human brain tumour biopsy samples using HR-MAS and ERETIC measurements
Published in NMR in biomedicine (01-02-2009)“…Accurate determination of the concentration of the metabolites contained in intact human biopsies of 10 glioblastoma multiforme samples was achieved using…”
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Nitrogen storage regulation by PII protein: lessons learned from taxonomic outliers
Published in The FEBS journal (01-02-2020)“…The paper ‘Interaction of N‐acetyl‐l‐glutamate kinase with the PII signal transducer in the non‐photosynthetic alga Polytomella parva: Co‐evolution towards a…”
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C‑2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV‑2 through Interaction with the Viral Spike (S) Protein
Published in Journal of medicinal chemistry (10-08-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, by infecting cells via the interaction of its spike protein (S) with the primary…”
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Correction: The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation
Published in PLoS pathogens (23-11-2022)“…[This corrects the article DOI: 10.1371/journal.ppat.1010631.]…”
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Infant hydrocephalus in sub-Saharan Africa: Impact of perioperative care in the Zanzibar archipelago
Published in Neurocirugia (Asturias, Spain) (01-09-2020)“…Child hydrocephalus in low- and middle-income countries represents one of the most sensitive ethical and health problems facing international health…”
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10
3D microsurgical anatomy of the cortico-spinal tract and lemniscal pathway based on fiber microdissection and demonstration with tractography
Published in Neurocirugía (Barcelona. Internet. English ed.) (01-11-2018)“…OBJECTIVETo demonstrate tridimensionally the anatomy of the cortico-spinal tract and the medial lemniscus, based on fiber microdissection and diffusion tensor…”
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3D anatomy of cerebellar peduncles based on fibre microdissection and a demonstration with tractography
Published in Neurocirugía (Asturias, Spain) (01-05-2017)“…To perform an anatomical and radiological study, using fibre microdissection and diffusion tensor tractography (DTT), to demonstrate the three-dimensionality…”
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12
Cervical intramedullary solitary fibrous tumor: Case report and review of the literature
Published in Surgical neurology international (29-12-2020)“…Background: Solitary fibrous tumors (SFTs) are benign tumors derived from mesenchymal tissues that predominantly occur in the pleura. Establishing the…”
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13
The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation
Published in PLoS pathogens (01-07-2022)“…The S:A222V point mutation, within the G clade, was characteristic of the 20E (EU1) SARS-CoV-2 variant identified in Spain in early summer 2020. This mutation…”
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14
The P II -NAGK-PipX-NtcA Regulatory Axis of Cyanobacteria: A Tale of Changing Partners, Allosteric Effectors and Non-covalent Interactions
Published in Frontiers in molecular biosciences (2018)“…P , a homotrimeric very ancient and highly widespread (bacteria, archaea, plants) key sensor-transducer protein, conveys signals of abundance or poorness of…”
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15
Infant hydrocephalus in sub-Saharan Africa: Impact of perioperative care in the Zanzibar archipelago
Published in Neurocirugía (Barcelona. Internet. English ed.) (01-09-2020)“…Child hydrocephalus in low- and middle-income countries represents one of the most sensitive ethical and health problems facing international health…”
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Journal Article -
16
A pure extradural hemangioblastoma mimicking a dumbbell nerve sheath tumor in cervical spine: illustrative case
Published in Journal of neurosurgery. Case lessons (02-08-2021)“…Spinal extradural hemangioblastomas (HBs) are quite uncommon, with most reported cases involving the thoracic and lumbar areas. Therefore, the presence of a…”
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17
3D microsurgical anatomy of the cortico-spinal tract and lemniscal pathway based on fibre microdissection and demonstration with tractography
Published in Neurocirugía (Barcelona. Internet. English ed.) (01-11-2018)“…To demonstrate tridimensionally the anatomy of the cortico-spinal tract and the medial lemniscus, based on fibre microdissection and diffusion tensor…”
Get full text
Journal Article -
18
3D anatomy of cerebellar peduncles based on fibre microdissection and a demonstration with tractography
Published in Neurocirugía (Barcelona. Internet. English ed.) (01-05-2017)“…To perform an anatomical and radiological study, using fibre microdissection and diffusion tensor tractography (DTT), to demonstrate the three-dimensionality…”
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19
Hidrocefalia infantil en el África subsahariana: impacto de los cuidados perioperatorios en el archipiélago de Zanzíbar
Published in Neurocirugía (Asturias, Spain) (01-09-2020)“…La hidrocefalia infantil en países de bajo y mediano ingreso, representa uno de los problemas éticos y sanitarios más conflictivos con los que se enfrenta el…”
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Anatomía microquirúrgica en 3D del tracto corticoespinal y de la vía del lemnisco basada en microdisección de fibras y demostración a través de tractografía
Published in Neurocirugía (Asturias, Spain) (01-11-2018)“…Realizar un estudio anatómico de microdisección de fibras y radiológico mediante tractografía basada en tensor de difusión (DTT) para demostrar…”
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