Search Results - "Ljungman, Per"

How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation by Einsele, Hermann, Ljungman, Per, Boeckh, Michael

“…Cytomegalovirus (CMV) reactivation remains one of the most common and life-threatening infectious complications following allogeneic hematopoietic stem cell…”
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The role of cytomegalovirus serostatus on outcome of hematopoietic stem cell transplantation by Ljungman, Per

“…PURPOSE OF REVIEWThe aim of this review is to discuss recent developments regarding the impact of cytomegalovirus (CMV) serological status of hematopoietic…”
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2013 IDSA Clinical Practice Guideline for Vaccination of the Immunocompromised Host by Rubin, Lorry G., Levin, Myron J., Ljungman, Per, Davies, E. Graham, Avery, Robin, Tomblyn, Marcie, Bousvaros, Athos, Dhanireddy, Shireesha, Sung, Lillian, Keyserling, Harry, Kang, Insoo

“…An international panel of experts prepared an evidenced-based guideline for vaccination of immunocompromised adults and children. These guidelines are intended…”
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Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation by Marty, Francisco M, Ljungman, Per, Chemaly, Roy F, Maertens, Johan, Dadwal, Sanjeet S, Duarte, Rafael F, Haider, Shariq, Ullmann, Andrew J, Katayama, Yuta, Brown, Janice, Mullane, Kathleen M, Boeckh, Michael, Blumberg, Emily A, Einsele, Hermann, Snydman, David R, Kanda, Yoshinobu, DiNubile, Mark J, Teal, Valerie L, Wan, Hong, Murata, Yoshihiko, Kartsonis, Nicholas A, Leavitt, Randi Y, Badshah, Cyrus

“…CMV infection is a common complication in patients undergoing hematopoietic-cell transplantation. The incidence of CMV infection was 23 percentage points lower…”
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Long-term results and GvHD after prophylactic and preemptive donor lymphocyte infusion after allogeneic stem cell transplantation for acute leukemia by Schmid, Christoph, Labopin, Myriam, Schaap, Nicolaas, Veelken, Hendrik, Brecht, Arne, Stadler, Michael, Finke, Juergen, Baron, Frederic, Collin, Matthew, Bug, Gesine, Ljungman, Per, Blaise, Didier, Tischer, Johanna, Bloor, Adrian, Kulagin, Aleksander, Giebel, Sebastian, Gorin, Norbert-Claude, Esteve, Jordi, Ciceri, Fabio, Savani, Bipin, Nagler, Arnon, Mohty, Mohamad

“…We report on 318 patients with acute leukemia, receiving donor lymphocyte infusion (DLI) in complete hematologic remission (CHR) after allogeneic stem cell…”
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Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors by Styczyński, Jan, Tridello, Gloria, Koster, Linda, Iacobelli, Simona, van Biezen, Anja, van der Werf, Steffie, Mikulska, Małgorzata, Gil, Lidia, Cordonnier, Catherine, Ljungman, Per, Averbuch, Diana, Cesaro, Simone, de la Camara, Rafael, Baldomero, Helen, Bader, Peter, Basak, Grzegorz, Bonini, Chiara, Duarte, Rafael, Dufour, Carlo, Kuball, Jurgen, Lankester, Arjan, Montoto, Silvia, Nagler, Arnon, Snowden, John A., Kröger, Nicolaus, Mohty, Mohamad, Gratwohl, Alois

“…Information on incidence, and factors associated with mortality is a prerequisite to improve outcome after hematopoietic stem cell transplantation (HSCT)…”
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The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy by Ljungman, Per, Mikulska, Malgorzata, de la Camara, Rafael, Basak, Grzegorz W., Chabannon, Christian, Corbacioglu, Selim, Duarte, Rafael, Dolstra, Harry, Lankester, Arjan C., Mohty, Mohamad, Montoto, Silvia, Murray, John, Peffault de Latour, Régis, Snowden, John A., Yakoub-Agha, Ibrahim, Verhoeven, Bregje, Kröger, Nicolaus, Styczynski, Jan

“…The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the…”
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COVID-19 and stem cell transplantation; results from an EBMT and GETH multicenter prospective survey by Ljungman, Per, de la Camara, Rafael, Mikulska, Malgorzata, Tridello, Gloria, Aguado, Beatriz, Zahrani, Mohsen Al, Apperley, Jane, Berceanu, Ana, Bofarull, Rodrigo Martino, Calbacho, Maria, Ciceri, Fabio, Lopez-Corral, Lucia, Crippa, Claudia, Fox, Maria Laura, Grassi, Anna, Jimenez, Maria-Jose, Demir, Safiye Koçulu, Kwon, Mi, Llamas, Carlos Vallejo, Lorenzo, José Luis López, Mielke, Stephan, Orchard, Kim, Porras, Rocio Parody, Vallisa, Daniele, Xhaard, Alienor, Knelange, Nina Simone, Cedillo, Angel, Kröger, Nicolaus, Piñana, José Luis, Styczynski, Jan

“…This study reports on 382 COVID-19 patients having undergone allogeneic ( n  = 236) or autologous ( n  = 146) hematopoietic cell transplantation (HCT) reported…”
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Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel by de Witte, Theo, Bowen, David, Robin, Marie, Malcovati, Luca, Niederwieser, Dietger, Yakoub-Agha, Ibrahim, Mufti, Ghulam J., Fenaux, Pierre, Sanz, Guillermo, Martino, Rodrigo, Alessandrino, Emilio Paolo, Onida, Francesco, Symeonidis, Argiris, Passweg, Jakob, Kobbe, Guido, Ganser, Arnold, Platzbecker, Uwe, Finke, Jürgen, van Gelder, Michel, van de Loosdrecht, Arjan A., Ljungman, Per, Stauder, Reinhard, Volin, Liisa, Deeg, H.Joachim, Cutler, Corey, Saber, Wael, Champlin, Richard, Giralt, Sergio, Anasetti, Claudio, Kröger, Nicolaus

“…An international expert panel, active within the European Society for Blood and Marrow Transplantation, European LeukemiaNet, Blood and Marrow Transplant…”
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Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines by Styczynski, Jan, van der Velden, Walter, Fox, Christopher P, Engelhard, Dan, de la Camara, Rafael, Cordonnier, Catherine, Ljungman, Per

“…Epstein-Barr virus-related post-transplant lymphoproliferative disorders are recognized as a significant cause of morbidity and mortality in patients…”
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Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials by Chemaly, Roy F, Chou, Sunwen, Einsele, Hermann, Griffiths, Paul, Avery, Robin, Razonable, Raymund R, Mullane, Kathleen M, Kotton, Camille, Lundgren, Jens, Komatsu, Takashi E, Lischka, Peter, Josephson, Filip, Douglas, Cameron M, Umeh, Obi, Miller, Veronica, Ljungman, Per

“…Standardized consensus definitions for resistant and refractory cytomegalovirus (CMV) infections and diseases in transplant recipients were developed by the…”
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Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma by Nahi, Hareth, Chrobok, Michael, Gran, Charlotte, Lund, Johan, Gruber, Astrid, Gahrton, Gösta, Ljungman, Per, Wagner, Arnika Kathleen, Alici, Evren

“…Treatment with Daratumumab (Dara), a monoclonal anti-CD38 antibody of IgG1 subtype, is effective in patients with multiple myeloma (MM). However, Dara also…”
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Cytomegalovirus in Hematopoietic Stem Cell Transplant Recipients by Ljungman, Per, MD, PhD, Hakki, Morgan, MD, Boeckh, Michael, MD

“…This article examines the clinical manifestations of and risk factors for cytomegalovirus (CMV). Prevention of CMV infection and disease are also explored…”
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A Mortality Analysis of Letermovir Prophylaxis for Cytomegalovirus (CMV) in CMV-seropositive Recipients of Allogeneic Hematopoietic Cell Transplantation by Ljungman, Per, Schmitt, Michael, Marty, Francisco M, Maertens, Johan, Chemaly, Roy F, Kartsonis, Nicholas A, Butterton, Joan R, Wan, Hong, Teal, Valerie L, Sarratt, Kendra, Murata, Yoshihiko, Leavitt, Randi Y, Badshah, Cyrus

“…Abstract Background In a phase 3 trial, letermovir reduced clinically significant cytomegalovirus infections (CS-CMVi) and all-cause mortality at week 24…”
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Use of letermovir in off-label indications: Infectious Diseases Working Party of European Society of Blood and Marrow Transplantation retrospective study by Styczyński, Jan, Tridello, Gloria, Xhaard, Alienor, Medinger, Michael, Mielke, Stephan, Taskinen, Mervi, Blijlevens, Nicole, Rodriguez, M. Aranzazu Bermudez, Solano, Carlos, Nikolousis, Emmanouil, Biffi, Alessandra, Groll, Andreas H., Junghanss, Christian, Tsirigotis, Panagiotis, Lioure, Bruno, Šrámek, Jiří, Holler, Ernst, Galaverna, Federica, Fagioli, Franca, Knelange, Nina, Wendel, Lotus, Gil, Lidia, de la Camara, Rafael, Mikulska, Malgorzata, Ljungman, Per

“…Letermovir (LMV) is licensed for prophylaxis of CMV infection in allogeneic hematopoietic cell transplant adult CMV-seropositive patients. Due to its favorable…”
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Donor Cytomegalovirus Status Influences the Outcome of Allogeneic Stem Cell Transplant: A Study by the European Group for Blood and Marrow Transplantation by Ljungman, Per, Brand, Ronald, Hoek, Jennifer, de la Camara, Rafael, Cordonnier, Catherine, Einsele, Hermann, Styczynski, Jan, Ward, Katherine N., Cesaro, Simone

“…Background. The use of a cytomegalovirus (CMV)–seronegative donor for a CMV-seronegative allogeneic hematopoietic stem cell transplant (HSCT) recipient is…”
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Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML by Björklund, Andreas T, Carlsten, Mattias, Sohlberg, Ebba, Liu, Lisa L, Clancy, Trevor, Karimi, Mohsen, Cooley, Sarah, Miller, Jeffrey S, Klimkowska, Monika, Schaffer, Marie, Watz, Emma, Wikström, Kristina, Blomberg, Pontus, Wahlin, Björn Engelbrekt, Palma, Marzia, Hansson, Lotta, Ljungman, Per, Hellström-Lindberg, Eva, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan

“…To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-cell-based therapy in primary chemotherapy-refractory or relapsed high-risk…”
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Poor outcome of patients with COVID-19 after CAR T-cell therapy for B-cell malignancies: results of a multicenter study on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Infectious Diseases Working Party and the European Hematology Association (EHA) Lymphoma Group by Spanjaart, Anne Mea, Ljungman, Per, de La Camara, Rafael, Tridello, Gloria, Ortiz-Maldonado, Valentín, Urbano-Ispizua, Alvaro, Barba, Pere, Kwon, Mi, Caballero, Dolores, Sesques, Pierre, Bachy, Emmanuel, Di Blasi, Roberta, Thieblemont, Catherine, Calkoen, Friso, Mutsaers, Pim, Maertens, Johan, Giannoni, Livia, Nicholson, Emma, Collin, Matthew, Vaz, Carlos Pinho, Metafuni, Elisabetta, Martinez-Lopez, Joaquin, Dignan, Fiona L., Ribera, Josep-Maria, Nagler, Arnon, Folber, Frantisek, Sanderson, Robin, Bloor, Adrian, Ciceri, Fabio, Knelange, Nina, Ayuk, Francis, Kroger, Nicolaus, Kersten, Marie José, Mielke, Stephan

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Allogeneic stem cell transplantation for chronic myeloid leukemia in the TKI era: population-based data from the Swedish CML registry by Lübking, Anna, Dreimane, Arta, Sandin, Fredrik, Isaksson, Cecilia, Märkevärn, Berit, Brune, Mats, Ljungman, Per, Lenhoff, Stig, Stenke, Leif, Höglund, Martin, Richter, Johan, Olsson-Strömberg, Ulla

“…Two decades after the introduction of tyrosine kinase inhibitors (TKI), a sizeable portion of patients with chronic myeloid leukemia (CML) in chronic phase…”
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NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs by Béziat, Vivien, Liu, Lisa L., Malmberg, Jenny-Ann, Ivarsson, Martin A., Sohlberg, Ebba, Björklund, Andreas T., Retière, Christelle, Sverremark-Ekström, Eva, Traherne, James, Ljungman, Per, Schaffer, Marie, Price, David A., Trowsdale, John, Michaëlsson, Jakob, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan

“…Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their interactions with HLA class I…”
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