Search Results - "Ljunggren, Osten"
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Effects of Dapagliflozin on Body Weight, Total Fat Mass, and Regional Adipose Tissue Distribution in Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Metformin
Published in The journal of clinical endocrinology and metabolism (01-03-2012)“…Context: Dapagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, reduces hyperglycemia in patients with type 2 diabetes mellitus (T2DM) by…”
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2
Complications and adverse effects related to surgical and medical treatment in patients with inflammatory bowel disease in a prospectively recruited population-based cohort
Published in Scandinavian journal of gastroenterology (02-11-2021)“…Medical adverse effects and surgical complications have been reported during treatment of patients with inflammatory bowel diseases (IBDs). There is however a…”
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3
Fibroblast growth factor-23 regulates parathyroid hormone and 1α-hydroxylase expression in cultured bovine parathyroid cells
Published in Journal of endocrinology (01-10-2007)“…Fibroblast growth factor-23 (FGF23) is a circulating factor that decreases serum levels of inorganic phosphate (Pi) as well as 1,25-dihydroxyvitamin D3. Recent…”
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4
Low Serum Testosterone and Estradiol Predict Mortality in Elderly Men
Published in The journal of clinical endocrinology and metabolism (01-07-2009)“…Context: Age-related reduction of serum testosterone may contribute to the signs and symptoms of aging, but previous studies report conflicting evidence about…”
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5
Falls Predict Fractures Independently of FRAX Probability: A Meta‐Analysis of the Osteoporotic Fractures in Men (MrOS) Study
Published in Journal of bone and mineral research (01-03-2018)“…ABSTRACT Although prior falls are a well‐established predictor of future fracture, there is currently limited evidence regarding the specific value of falls…”
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6
Plasma Osteocalcin Is Inversely Related to Fat Mass and Plasma Glucose in Elderly Swedish Men
Published in Journal of bone and mineral research (01-05-2009)“…The osteoblast‐derived protein osteocalcin has recently been shown to affect adiposity and glucose homeostasis in mice, suggesting that the skeleton influences…”
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THERAPY OF ENDOCRINE DISEASE: Treatment of osteogenesis imperfecta in adults
Published in European journal of endocrinology (01-08-2014)“…BackgroundOsteogenesis imperfecta (OI) is a heterogeneous rare connective tissue disorder commonly caused by mutations in the collagen type I genes…”
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High doses of cholecalciferol alleviate the progression of hyperparathyroidism in patients with CKD Stages 3-4: results of a 12-week double-blind, randomized, controlled study
Published in Nephrology, dialysis, transplantation (01-03-2018)“…Calcidiol insufficiency may accelerate the development of secondary hyperparathyroidism (SHPT). We tested the effect of a substantial increase in calcidiol on…”
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9
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure
Published in PLoS genetics (01-02-2013)“…Most previous genetic epidemiology studies within the field of osteoporosis have focused on the genetics of the complex trait areal bone mineral density…”
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10
Dehydroepiandrosterone and its Sulfate Predict the 5-Year Risk of Coronary Heart Disease Events in Elderly Men
Published in Journal of the American College of Cardiology (28-10-2014)“…Abstract Background The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid…”
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11
Genetic epidemiology, prevalence, and genotype-phenotype correlations in the Swedish population with osteogenesis imperfecta
Published in European journal of human genetics : EJHG (01-08-2015)“…Osteogenesis imperfecta (OI) is a rare hereditary bone fragility disorder, caused by collagen I mutations in 90% of cases. There are no comprehensive…”
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12
Increased plasma levels of soluble programmed death ligand 1 (sPD-L1) and fibroblast growth factor 23 (FGF-23) in patients with Graves’ ophthalmopathy in comparison to hyperthyroid patients without Graves’ ophthalmopathy
Published in Cytokine (Philadelphia, Pa.) (01-09-2023)“…Management of Graves’ ophthalmopathy (GO) is still a challenge in Graves’ disease (GD). Moreover, 40% of GD patients show radiological muscle enlargement…”
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13
Serum Glycine Levels Are Associated With Cortical Bone Properties and Fracture Risk in Men
Published in The journal of clinical endocrinology and metabolism (01-12-2021)“…In a recent study a pattern of 27 metabolites, including serum glycine, associated with bone mineral density (BMD). To investigate associations for serum and…”
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14
Genetic determinants of serum testosterone concentrations in men
Published in PLoS genetics (01-10-2011)“…Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity…”
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15
Effects of glucocorticoids on vitamin D3-metabolizing 24-hydroxylase (CYP24A1) in Saos-2 cells and primary human osteoblasts
Published in Molecular and cellular endocrinology (01-10-2019)“…Vitamin D is essential for bone function and deficiency in active vitamin D hormone can lead to bone disorders. Long-term treatment with glucocorticoids…”
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The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study
Published in Osteoporosis international (2022)“…Summary In this prospective study in Swedish elderly men, PAD based on an ABI < 0.9 was associated with an increased risk of hip fracture, independent of age…”
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High‐Sensitivity CRP Is an Independent Risk Factor for All Fractures and Vertebral Fractures in Elderly Men: The MrOS Sweden Study
Published in Journal of bone and mineral research (01-02-2014)“…ABSTRACT Epidemiological studies have shown low‐grade inflammation measured by high‐sensitivity C‐reactive protein (hs‐CRP) to be associated with fracture risk…”
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18
Low Serum Levels of Dehydroepiandrosterone Sulfate Predict All-Cause and Cardiovascular Mortality in Elderly Swedish Men
Published in The journal of clinical endocrinology and metabolism (01-09-2010)“…Context: The age-related decline in dehydroepiandrosterone (DHEA) levels is thought to be of importance for general and vascular aging. However, data on the…”
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19
Comparison Between Thyroid Stimulating Immunoglobulin and TSH-Receptor Antibodies in the Management of Graves' Orbitopathy
Published in Experimental and clinical endocrinology & diabetes (01-04-2023)“…TSH-receptor antibodies (TRAb) targeting the TSH receptor (TSH-R) induce hyperthyroidism in Graves´ disease (GD). Graves´ orbitopathy (GO) is influenced by…”
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3D Finite Element Models Reconstructed From 2D Dual-Energy X-Ray Absorptiometry (DXA) Images Improve Hip Fracture Prediction Compared to Areal BMD in Osteoporotic Fractures in Men (MrOS) Sweden Cohort
Published in Journal of bone and mineral research (01-09-2023)“…Bone strength is an important contributor to fracture risk. Areal bone mineral density (aBMD) derived from dual-energy X-ray absorptiometry (DXA) is used as a…”
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