Search Results - "Ljunggren, östen"

A Meta‐Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX by McCloskey, Eugene V, Odén, Anders, Harvey, Nicholas C, Leslie, William D, Hans, Didier, Johansson, Helena, Barkmann, Reinhard, Boutroy, Stephanie, Brown, Jacques, Chapurlat, Roland, Elders, Petra JM, Fujita, Yuki, Glüer, Claus‐C, Goltzman, David, Iki, Masayuki, Karlsson, Magnus, Kindmark, Andreas, Kotowicz, Mark, Kurumatani, Norio, Kwok, Timothy, Lamy, Oliver, Leung, Jason, Lippuner, Kurt, Ljunggren, Östen, Lorentzon, Mattias, Mellström, Dan, Merlijn, Thomas, Oei, Ling, Ohlsson, Claes, Pasco, Julie A, Rivadeneira, Fernando, Rosengren, Björn, Sornay‐Rendu, Elisabeth, Szulc, Pawel, Tamaki, Junko, Kanis, John A

“…ABSTRACT Trabecular bone score (TBS) is a gray‐level textural index of bone microarchitecture derived from lumbar spine dual‐energy X‐ray absorptiometry (DXA)…”
Get full text

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture by Forgetta, Vincenzo, Estrada, Karol, Leo, Paul J., Dahia, Chitra L., Liu, Ching‐Ti, Uggla, Charlotta, Evans, Daniel S., Walter, Klaudia, Pettersson‐Kymmer, Ulrika, McCarthy, Shane, Kwan, Tony, Jhamai, Mila, Trajanoska, Katerina, Huang, Jie, Danecek, Petr, Wilmot, Beth, Li, Rui, Moayyeri, Alireza, Claussnitzer, Melina, Cheng, Chia‐Ho, Cheung, Warren, Ge, Bing, Chen, Shu‐Huang, Choi, Kwangbom, Oei, Ling, Fraser, James, Hibbs, Matthew A., Gregson, Celia L., Paquette, Denis, Wibom, Carl, Tranah, Gregory J., Marshall, Mhairi, Gardiner, Brooke B., Cremin, Katie, Auer, Paul, Hsu, Li, Thorleifsson, Gudmar, Enneman, Anke W., de Groot, Lisette C. P. G. M., Melin, Beatrice, Christiansen, Claus, Sayers, Adrian, Zhou, Yanhua, Calderari, Sophie, van Rooij, Jeroen, Carlson, Chris, Peters, Ulrike, Uitterlinden, Andre G., Williams, Stephen R., Farber, Charles, Grinberg, Daniel, Chasman, Daniel I., Giulianini, Franco, Ridker, Paul M., Eisman, John A., Nguyen, Tuan V., Center, Jacqueline R., Garcia‐Giralt, Natalia, Mellström, Dan, Vandenput, Liesbeth, Amin, Najaf, van Duijn, Cornelia M., Karlsson, Magnus K., Svensson, Olle, Rousseau, François, Bussière, Johanne, Koromani, Fjorda, Langdahl, Bente L., Jensen, Jens‐Erik B., Kaptoge, Stephen, Khaw, Kay‐Tee, Reeve, Jonathan, Xuereb‐Anastasi, Angela, Åkesson, Kristina, Olmos, Jose M., Zarrabeitia, Maria T., Riancho, Jose A., Alonso, Nerea, Jiang, Xi, Goltzman, David, Grundberg, Elin, Gauguier, Dominique, Orwoll, Eric S., Karasik, David, Davey‐Smith, George, Smith, Albert V., Harris, Tamara B., Carola Zillikens, M., Thorsteinsdottir, Unnur, Soranzo, Nicole, Durbin, Richard, Brown, Matthew A., Spector, Tim, Adrienne Cupples, L., Greenwood, Celia M. T., Jackson, Rebecca D., Rowe, David W., Loomis, Cynthia A., Ackert‐Bicknell, Cheryl L., Kiel, Douglas P.

“…Human population genomic studies, including whole‐genome sequencing, were undertaken to identify determinants of bone mineral density (BMD), a major predictor…”
Get full text

Effects of denosumab on fracture and bone mineral density by level of kidney function by Jamal, Sophie A, Ljunggren, Östen, Stehman‐Breen, Catherine, Cummings, Steven Ron, McClung, Michael R, Goemaere, Stefan, Ebeling, Peter R, Franek, Edward, Yang, Yu‐ching, Egbuna, Ogo I, Boonen, Steven, Miller, Paul D

“…The incidences of osteoporosis and chronic kidney disease (CKD) both increase with increasing age, yet there is a paucity of data on treatments for…”
Get full text

Transgenic Mice Expressing Fibroblast Growth Factor 23 under the Control of the α1(I) Collagen Promoter Exhibit Growth Retardation, Osteomalacia, and Disturbed Phosphate Homeostasis by Larsson, Tobias, Marsell, Richard, Schipani, Ernestina, Ohlsson, Claes, Ljunggren, Östen, Tenenhouse, Harriet S, Jüppner, Harald, Jonsson, Kenneth B

“…Mutations in the fibroblast growth factor 23 gene, FGF23, cause autosomal dominant hypophosphatemic rickets (ADHR). The gene product, FGF-23, is produced by…”
Get full text

High Serum Testosterone Is Associated With Reduced Risk of Cardiovascular Events in Elderly Men: The MrOS (Osteoporotic Fractures in Men) Study in Sweden by OHLSSON, Claes, BARRETT-CONNOR, Elizabeth, BHASIN, Shalender, ORWOLL, Eric, LABRIE, Fernand, KARLSSON, Magnus K, LJUNGGREN, Osten, VANDENPUT, Liesbeth, MELLSTRÖM, Dan, TIVESTEN, Asa

“…We tested the hypothesis that serum total testosterone and sex hormone-binding globulin (SHBG) levels predict cardiovascular (CV) events in community-dwelling…”
Get full text

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture by Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Ntzani, Evangelia E, Albagha, Omar M E, Koller, Daniel L, Minster, Ryan L, Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Zheng, Hou-Feng, Alonso, Nerea, Kammerer, Candace M, Kaptoge, Stephen K, Leo, Paul J, Wilson, James F, Alen, Markku, Aspelund, Thor, Center, Jacqueline R, Dailiana, Zoe, Duggan, David J, Garcia, Melissa, Husted, Lise Bjerre, Jameson, Karen A, Kim, Ghi Su, Kooperberg, Charles, Kruk, Marcin, Laaksonen, Marika, Leung, Ping C, Lewis, Joshua R, Nogues, Xavier, Prezelj, Janez, Scollen, Serena, Svensson, Olle, Trompet, Stella, Woo, Jean, Zhu, Kun, Cheng, Sulin, Dedoussis, George, Frost, Morten, Goltzman, David, Kähönen, Mika, Karlsson, Magnus, Langdahl, Bente Lomholt, Lips, Paul, Lorenc, Roman S, Mellström, Dan, Olmos, José M, Pettersson-Kymmer, Ulrika, Riancho, José A, Ridker, Paul M, Rousseau, François, lagboom, P Eline S, Urreizti, Roser, Zarrabeitia, María T, Castano-Betancourt, Martha, Kwan, Tony, Li, Rui, Luben, Robert, Medina-Gómez, Carolina, Th Palsson, Stefan, Rotter, Jerome I, Sigurdsson, Gunnar, van Meurs, Joyce B J, Williams, Frances M K, Zhou, Yanhua, Pastinen, Tomi, Cauley, Jane A, Chasman, Daniel I, Clark, Graeme R, Cummings, Steven R, Eastell, Richard, Eisman, John A, Hofman, Albert, Jukema, J Wouter, Khaw, Kay-Tee, Lehtimäki, Terho, Liu, Yongmei, Oostra, Ben A, Pols, Huibert A P, Reid, Ian R, Robbins, John, Sambrook, Philip N, Sham, Pak Chung, Shuldiner, Alan R, van Duijn, Cornelia M, Wareham, Nick J, Econs, Michael J, Harris, Tamara B, Kung, Annie Wai Chee, Streeten, Elizabeth A, Thorsteinsdottir, Unnur, Karasik, David, Richards, J Brent, Brown, Matthew A, Ralston, Stuart H, Ioannidis, John P A, Kiel, Douglas P

“…Fernando Rivadeneira and colleagues in the Genetic Factors for Osteoporosis Consortium report a large-scale meta-analysis identifying new loci associated with…”
Get full text

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies by Sarwar, Nadeem, Butterworth, Adam S, Freitag, Daniel F, Gregson, John, Willeit, Peter, Gorman, Donal N, Gao, Pei, Saleheen, Danish, Rendon, Augusto, Nelson, Christopher P, Braund, Peter S, Hall, Alistair S, Chasman, Daniel I, Tybjærg-Hansen, Anne, Chambers, John C, Benjamin, Emelia J, Franks, Paul W, Clarke, Robert, Wilde, Arthur A M, Trip, Mieke D, Steri, Maristella, Witteman, Jacqueline C M, Qi, Lu, van der Schoot, C Ellen, de Faire, Ulf, Erdmann, Jeanette, Stringham, Heather M, Koenig, Wolfgang, Rader, Daniel J, Melzer, David, Reich, David, Psaty, Bruce M, Kleber, Marcus E, Panagiotakos, Demosthenes B, Willeit, Johann, Wennberg, Patrik, Woodward, Mark, Adamovic, Svetlana, Rimm, Eric B, Meade, Tom W, Gillum, Richard F, Shaffer, Jonathan A, Hofman, Albert, Onat, Altan, Sundström, Johan, Wassertheil-Smoller, Sylvia, Mellström, Dan, Gallacher, John, Cushman, Mary, Tracy, Russell P, Kauhanen, Jussi, Karlsson, Magnus, Salonen, Jukka T, Wilhelmsen, Lars, Amouyel, Philippe, Cantin, Bernard, Best, Lyle G, Ben-Shlomo, Yoav, Manson, JoAnn E, Davey-Smith, George, de Bakker, Paul I W, O'Donnell, Christopher J, Wilson, James F, Wilson, Anthony G, Assimes, Themistocles L, Jansson, John-Olov, Ohlsson, Claes, Tivesten, Åsa, Ljunggren, Östen, Reilly, Muredach P, Hamsten, Anders, Ingelsson, Erik, Cambien, Francois, Hung, Joseph, Thomas, G Neil, Boehnke, Michael, Schunkert, Heribert, Asselbergs, Folkert W, Kastelein, John J P, Gudnason, Vilmundur, Salomaa, Veikko, Harris, Tamara B, Kooner, Jaspal S, Allin, Kristine H, Nordestgaard, Børge G, Hopewell, Jemma C, Goodall, Alison H, Ridker, Paul M, Hólm, Hilma, Watkins, Hugh, Ouwehand, Willem H, Samani, Nilesh J, Kaptoge, Stephen, Di Angelantonio, Emanuele, Harari, Olivier, Danesh, John

“…Summary Background Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6…”
Get full text

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile by Loos, Ruth J F, Kilpeläinen, Tuomas O, Zillikens, M Carola, Stan ákova, Alena, Finucane, Francis M, Langenberg, Claudia, Zhang, Weihua, Beckmann, Jacques S, Luan, Jian'an, Vandenput, Liesbeth, Styrkarsdottir, Unnur, Zhou, Yanhua, Smith, Albert Vernon, Zhao, Jing-Hua, Amin, Najaf, Shin, So-Youn, Haritunians, Talin, Fu, Mao, Feitosa, Mary F, Kumari, Meena, Halldorsson, Bjarni V, Tikkanen, Emmi, Mangino, Massimo, Hayward, Caroline, Song, Ci, Arnold, Alice M, Aulchenko, Yurii S, Oostra, Ben A, Campbell, Harry, Cupples, L Adrienne, Davis, Kathryn E, Döring, Angela, Eiriksdottir, Gudny, Estrada, Karol, Fernández-Real, José Manuel, Garcia, Melissa, Gieger, Christian, Guiducci, Candace, Hofman, Albert, Isomaa, Bo, Jacobs, Leonie C, Jula, Antti, Karasik, David, Karlsson, Magnus K, Khaw, Kay-Tee, Kim, Lauren J, Kühnel, Brigitte, Kuusisto, Johanna, Liu, Yongmei, Ljunggren, Östen, Lorentzon, Mattias, Luben, Robert N, Mellström, Dan, Mitchell, Braxton D, Mooser, Vincent, Moreno, José Maria, O'Connell, Jeffery R, Pascoe, Laura, Peltonen, Leena, Peral, Belén, Perola, Markus, Salomaa, Veikko, Semple, Robert K, Skaric-Juric, Tatjana, Sigurdsson, Gunnar, Song, Kijoung S, Spector, Timothy D, Syvänen, Ann-Christine, Talmud, Philippa J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Uitterlinden, André G, van Duijn, Cornelia M, Vidal-Puig, Antonio, Wild, Sarah H, Clegg, Deborah J, Schadt, Eric, Wilson, James F, Ripatti, Samuli, Borecki, Ingrid B, Shuldiner, Alan R, Jansson, John-Olov, Kaplan, Robert C, Gudnason, Vilmundur, Harris, Tamara B, Groop, Leif, Kiel, Douglas P, Rivadeneira, Fernando, Walker, Mark, Vollenweider, Peter, Waeber, Gérard, Chambers, John C, Kooner, Jaspal S, Soranzo, Nicole, Hirschhorn, Joel N, Ohlsson, Claes, Wareham, Nicholas J, Speliotes, Elizabeth K, Fox, Caroline S, Laakso, Markku

“…Ruth Loos and colleagues use genome-wide association to identify common variants influencing body fat percentage. Unexpectedly, they show that a…”
Get full text

Fibroblast Growth Factor 23 in Oncogenic Osteomalacia and X-Linked Hypophosphatemia by Jonsson, Kenneth B, Zahradnik, Richard, Larsson, Tobias, White, Kenneth E, Sugimoto, Toshitsugu, Imanishi, Yasuo, Yamamoto, Takehisa, Hampson, Geeta, Koshiyama, Hiroyuki, Ljunggren, Östen, Oba, Koichi, Yang, In Myung, Miyauchi, Akimitsu, Econs, Michael J, Lavigne, Jeffrey, Jüppner, Harald

“…Fibroblast growth factor 23 (FGF-23) appears to be involved in phosphate regulation by the kidney. It has been hypothesized that this factor is elevated in…”
Get full text

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation by Coviello, Andrea D, Haring, Robin, Wellons, Melissa, Vaidya, Dhananjay, Lehtimäki, Terho, Keildson, Sarah, Lunetta, Kathryn L, He, Chunyan, Fornage, Myriam, Lagou, Vasiliki, Mangino, Massimo, Onland-Moret, N Charlotte, Chen, Brian, Eriksson, Joel, Garcia, Melissa, Liu, Yong Mei, Koster, Annemarie, Lohman, Kurt, Lyytikäinen, Leo-Pekka, Petersen, Ann-Kristin, Prescott, Jennifer, Stolk, Lisette, Vandenput, Liesbeth, Wood, Andrew R, Zhuang, Wei Vivian, Ruokonen, Aimo, Hartikainen, Anna-Liisa, Pouta, Anneli, Bandinelli, Stefania, Biffar, Reiner, Brabant, Georg, Cox, David G, Chen, Yuhui, Cummings, Steven, Ferrucci, Luigi, Gunter, Marc J, Hankinson, Susan E, Martikainen, Hannu, Hofman, Albert, Homuth, Georg, Illig, Thomas, Jansson, John-Olov, Johnson, Andrew D, Karasik, David, Karlsson, Magnus, Kettunen, Johannes, Kiel, Douglas P, Kraft, Peter, Liu, Jingmin, Ljunggren, Östen, Lorentzon, Mattias, Maggio, Marcello, Markus, Marcello R P, Mellström, Dan, Miljkovic, Iva, Mirel, Daniel, Nelson, Sarah, Morin Papunen, Laure, Peeters, Petra H M, Prokopenko, Inga, Raffel, Leslie, Reincke, Martin, Reiner, Alex P, Rexrode, Kathryn, Rivadeneira, Fernando, Schwartz, Stephen M, Siscovick, David, Soranzo, Nicole, Stöckl, Doris, Tworoger, Shelley, Uitterlinden, André G, van Gils, Carla H, Vasan, Ramachandran S, Wichmann, H-Erich, Zhai, Guangju, Bhasin, Shalender, Bidlingmaier, Martin, Chanock, Stephen J, De Vivo, Immaculata, Harris, Tamara B, Hunter, David J, Kähönen, Mika, Liu, Simin, Ouyang, Pamela, Spector, Tim D, van der Schouw, Yvonne T, Viikari, Jorma, Wallaschofski, Henri, McCarthy, Mark I, Frayling, Timothy M, Murray, Anna, Franks, Steve, Järvelin, Marjo-Riitta, de Jong, Frank H, Raitakari, Olli, Teumer, Alexander, Ohlsson, Claes, Murabito, Joanne M, Perry, John R B

“…Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone…”
Get full text

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium by Moayyeri, Alireza, Hsu, Yi-Hsiang, Karasik, David, Xiao, Su-Mei, Nielson, Carrie, Srikanth, Priya, Giroux, Sylvie, Wilson, Scott G., Zheng, Hou-Feng, Smith, Albert V., Pye, Stephen R., Teumer, Alexander, Hwang, Joo-Yeon, McGuigan, Fiona, Minster, Ryan L., Lyytikäinen, Leo-Pekka, Swart, Karin M.A., Masi, Laura, Oldmeadow, Chris, Cheng, Sulin, Harvey, Nicholas C., Kruk, Marcin, del Greco M, Fabiola, Igl, Wilmar, Luben, Robert, Liu, Ching-Ti, Oei, Ling, Medina-Gomez, Carolina, Zmuda, Joseph, Tranah, Greg, Brown, Suzanne J., Williams, Frances M., Soranzo, Nicole, Siggeirsdottir, Kristin, Hannemann, Anke, Go, Min Jin, Garcia, Melissa, Polasek, Ozren, Laaksonen, Marika, Zhu, Kun, Enneman, Anke W., McEvoy, Mark, Peel, Roseanne, Sham, Pak Chung, Jaworski, Maciej, Johansson, Åsa, Pludowski, Pawel, Scott, Rodney, Kähönen, Mika, Viikari, Jorma S., Sievänen, Harri, Raitakari, Olli T., Hernández, Jose L., Ljunggren, Östen, Völker, Uwe, Nauck, Matthias, Homuth, Georg, Haring, Robin, McCloskey, Eugene, Eastell, Richard, Jones, Graeme, Reid, Ian R., Dennison, Elaine M., Wark, John, Vanderschueren, Dirk, Aspelund, Thor, Richards, J. Brent, Bauer, Doug, Hofman, Albert, Khaw, Kay-Tee, Dedoussis, George, Obermayer-Pietsch, Barbara, Gyllensten, Ulf, Pramstaller, Peter P., Lorenc, Roman S., Cooper, Cyrus, Kung, Annie Wai Chee, Lips, Paul, Alen, Markku, Attia, John, Brandi, Maria Luisa, de Groot, Lisette C.P.G.M., Lehtimäki, Terho, Riancho, José A., Harris, Tamara B., Akesson, Kristina, Karlsson, Magnus, Lee, Jong-Young, Duncan, Emma L., O'Neill, Terence W., Gudnason, Vilmundur, Spector, Timothy D., Orwoll, Eric, Wareham, Nick J., Rivadeneira, Fernando, Uitterlinden, Andre G., Prince, Richard L., Kiel, Douglas P., Reeve, Jonathan, Kaptoge, Stephen K.

“…Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by…”
Get full text

Genetic Variants Associated with Circulating Fibroblast Growth Factor 23 by Robinson-Cohen, Cassianne, Bartz, Traci M, Lai, Dongbing, Ikizler, T Alp, Peacock, Munro, Imel, Erik A, Michos, Erin D, Foroud, Tatiana M, Akesson, Kristina, Taylor, Kent D, Malmgren, Linnea, Matsushita, Kunihiro, Nethander, Maria, Eriksson, Joel, Ohlsson, Claes, Mellström, Daniel, Wolf, Myles, Ljunggren, Osten, McGuigan, Fiona, Rotter, Jerome I, Karlsson, Magnus, Econs, Michael J, Ix, Joachim H, Lutsey, Pamela L, Psaty, Bruce M, de Boer, Ian H, Kestenbaum, Bryan R

“…Fibroblast growth factor 23 (FGF23), a bone-derived hormone that regulates phosphorus and vitamin D metabolism, contributes to the pathogenesis of mineral and…”
Get full text

Population genomics in a disease targeted primary cell model by Grundberg, Elin, Kwan, Tony, Ge, Bing, Lam, Kevin C L, Koka, Vonda, Kindmark, Andreas, Mallmin, Hans, Dias, Joana, Verlaan, Dominique J, Ouimet, Manon, Sinnett, Daniel, Rivadeneira, Fernando, Estrada, Karol, Hofman, Albert, van Meurs, Joyce M, Uitterlinden, André, Beaulieu, Patrick, Graziani, Alexandru, Harmsen, Eef, Ljunggren, Osten, Ohlsson, Claes, Mellström, Dan, Karlsson, Magnus K, Nilsson, Olle, Pastinen, Tomi

“…The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner…”
Get full text

Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis by van Meurs, Joyce B. J, Trikalinos, Thomas A, Ralston, Stuart H, Balcells, Susana, Brandi, Maria Luisa, Brixen, Kim, Kiel, Douglas P, Langdahl, Bente L, Lips, Paul, Ljunggren, Östen, Lorenc, Roman, Obermayer-Pietsch, Barbara, Ohlsson, Claes, Pettersson, Ulrika, Reid, David M, Rousseau, Francois, Scollen, Serena, Van Hul, Wim, Agueda, Lidia, Åkesson, Kristina, Benevolenskaya, Lidia I, Ferrari, Serge L, Hallmans, Göran, Hofman, Albert, Husted, Lise Bjerre, Kruk, Marcin, Kaptoge, Stephen, Karasik, David, Karlsson, Magnus K, Lorentzon, Mattias, Masi, Laura, McGuigan, Fiona E. A, Mellström, Dan, Mosekilde, Leif, Nogues, Xavier, Pols, Huibert A. P, Reeve, Jonathan, Renner, Wilfried, Rivadeneira, Fernando, van Schoor, Natasja M, Weber, Kurt, Ioannidis, John P. A, Uitterlinden, André G, GENOMOS Study, for the

“…CONTEXT Mutations in the low-density lipoprotein receptor–related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density…”
Get full text

Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men by Ohlsson, Claes, Nilsson, Maria E, Tivesten, Åsa, Ryberg, Henrik, Mellström, Dan, Karlsson, Magnus K, Ljunggren, Östen, Labrie, Fernand, Orwoll, Eric S, Lee, David M, Pye, Stephen R, O'Neill, Terence W, Finn, Joseph D, Adams, Judith E, Ward, Kate A, Boonen, Steven, Bartfai, Gyorgy, Casanueva, Felipe F, Forti, Gianni, Giwercman, Aleksander, Han, Thang S, Huhtaniemi, Ilpo T, Kula, Krzysztof, Lean, Michael E. J, Pendleton, Neil, Punab, Margus, Vanderschueren, Dirk, Wu, Frederick C. W, Vandenput, Liesbeth, the EMAS Study Group

“…Context: Immunoassay-based techniques, routinely used to measure serum estradiol (E2), are known to have reduced specificity, especially at lower…”
Get full text

Assessment of gene-by-sex interaction effect on bone mineral density by Liu, Ching-Ti, Estrada, Karol, Yerges-Armstrong, Laura M, Amin, Najaf, Evangelou, Evangelos, Li, Guo, Minster, Ryan L, Carless, Melanie A, Kammerer, Candace M, Oei, Ling, Zhou, Yanhua, Alonso, Nerea, Dailiana, Zoe, Eriksson, Joel, García-Giralt, Natalia, Giroux, Sylvie, Husted, Lise Bjerre, Khusainova, Rita I, Koromila, Theodora, Kung, Annie WaiChee, Lewis, Joshua R, Masi, Laura, Mencej-Bedrac, Simona, Nogues, Xavier, Patel, Millan S, Prezelj, Janez, Richards, J Brent, Sham, Pak Chung, Spector, Timothy, Vandenput, Liesbeth, Xiao, Su-Mei, Zheng, Hou-Feng, Zhu, Kun, Balcells, Susana, Brandi, Maria Luisa, Frost, Morten, Goltzman, David, González-Macías, Jesús, Karlsson, Magnus, Khusnutdinova, Elza K, Kollia, Panagoula, Langdahl, Bente Lomholt, Ljunggren, Östen, Lorentzon, Mattias, Marc, Janja, Mellström, Dan, Ohlsson, Claes, Olmos, José M, Ralston, Stuart H, Riancho, José A, Rousseau, François, Urreizti, Roser, Van Hul, Wim, Zarrabeitia, María T, Castano-Betancourt, Martha, Demissie, Serkalem, Grundberg, Elin, Herrera, Lizbeth, Kwan, Tony, Medina-Gómez, Carolina, Pastinen, Tomi, Sigurdsson, Gunnar, Thorleifsson, Gudmar, vanMeurs, Joyce BJ, Blangero, John, Hofman, Albert, Liu, Yongmei, Mitchell, Braxton D, O'Connell, Jeffrey R, Oostra, Ben A, Rotter, Jerome I, Stefansson, Kari, Streeten, Elizabeth A, Styrkarsdottir, Unnur, Thorsteinsdottir, Unnur, Tylavsky, Frances A, Uitterlinden, Andre, Cauley, Jane A, Harris, Tamara B, Ioannidis, John PA, Psaty, Bruce M, Robbins, John A, Zillikens, M Carola, vanDuijn, Cornelia M, Prince, Richard L, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas P, Cupples, L Adrienne, Hsu, Yi-Hsiang

“…Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex…”
Get full text

Effectiveness of Teriparatide in Postmenopausal Women with Osteoporosis and Glucocorticoid Use: 3-Year Results from the EFOS Study by KARRAS, Dimitrios, STOYKOV, Ivaylo, MARIN, Fernando, LEMS, Willem F, LANGDAHL, Bente L, LJUNGGREN, Osten, BARRETT, Annabel, BERNARD WALSH, J, FAHRLEITNER-PAMMER, Astrid, RAJZBAUM, Gerald, JAKOB, Franz

“…To describe clinical fracture rates, back pain, and health-related quality of life (HRQOL) in postmenopausal women with osteoporosis who are receiving…”
Get full text

Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus by Oei, Ling, Estrada, Karol, Duncan, Emma L, Christiansen, Claus, Liu, Ching-Ti, Langdahl, Bente L, Obermayer-Pietsch, Barbara, Riancho, José A, Prince, Richard L, van Schoor, Natasja M, McCloskey, Eugene, Hsu, Yi-Hsiang, Evangelou, Evangelos, Ntzani, Evangelia, Evans, David M, Alonso, Nerea, Husted, Lise B, Valero, Carmen, Hernandez, Jose L, Lewis, Joshua R, Kaptoge, Stephen K, Zhu, Kun, Cupples, L. Adrienne, Medina-Gómez, Carolina, Vandenput, Liesbeth, Kim, Ghi Su, Lee, Seung Hun, Castaño-Betancourt, Martha C, Oei, Edwin H.G, Martinez, Josefina, Daroszewska, Anna, van der Klift, Marjolein, Mellström, Dan, Herrera, Lizbeth, Karlsson, Magnus K, Hofman, Albert, Ljunggren, Östen, Pols, Huibert A.P, Stolk, Lisette, van Meurs, Joyce B.J, Ioannidis, John P.A, Zillikens, M. Carola, Lips, Paul, Karasik, David, Uitterlinden, André G, Styrkarsdottir, Unnur, Brown, Matthew A, Koh, Jung-Min, Richards, J. Brent, Reeve, Jonathan, Ohlsson, Claes, Ralston, Stuart H, Kiel, Douglas P, Rivadeneira, Fernando

“…Abstract Vertebral fracture risk is a heritable complex trait. The aim of this study was to identify genetic susceptibility factors for osteoporotic vertebral…”
Get full text

The Autosomal Dominant Hypophosphatemic Rickets (ADHR) Gene Is a Secreted Polypeptide Overexpressed by Tumors that Cause Phosphate Wasting by White, Kenneth E., Jonsson, Kenneth B., Carn, Gwenaelle, Hampson, Geeta, Spector, Tim D., Mannstadt, Michael, Lorenz-Depiereux, Bettina, Miyauchi, Akimitsu, Yang, In Myung, Ljunggren, Östen, Meitinger, Thomas, Strom, Tim M., Jüppner, Harald, Econs, Michael J.

“…The gene mutated in autosomal dominant hypophosphatemic rickets (ADHR), a phosphate wasting disorder, has been identified as FGF-23, a protein that shares…”
Get full text

Effects of Dapagliflozin on Body Weight, Total Fat Mass, and Regional Adipose Tissue Distribution in Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Metformin by Bolinder, Jan, Ljunggren, Östen, Kullberg, Joel, Johansson, Lars, Wilding, John, Langkilde, Anna Maria, Sugg, Jennifer, Parikh, Shamik

“…Context: Dapagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, reduces hyperglycemia in patients with type 2 diabetes mellitus (T2DM) by…”
Get full text