Search Results - "Ljungberg, M Cecilia"

Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier by Huang, Qin, Chen, Albert T, Chan, Ken Y, Sorensen, Hikari, Barry, Andrew J, Azari, Bahar, Zheng, Qingxia, Beddow, Thomas, Zhao, Binhui, Tobey, Isabelle G, Moncada-Reid, Cynthia, Eid, Fatma-Elzahraa, Walkey, Christopher J, Ljungberg, M Cecilia, Lagor, William R, Heaney, Jason D, Chan, Yujia A, Deverman, Benjamin E

“…Viruses have evolved the ability to bind and enter cells through interactions with a wide variety of cell macromolecules. We engineered peptide-modified…”
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VCAM1 Is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess by Candelaria, Nicholes R, Padmanabhan, Achuth, Stossi, Fabio, Ljungberg, M Cecilia, Shelly, Katharine E, Pew, Braden K, Solis, Minerva, Rossano, Ayane M, McAllister, Jan M, Wu, Sheng, Richards, JoAnne S

“…Abstract Ovarian theca androgen production is regulated by the pituitary LH and intrafollicular factors. Enhanced androgen biosynthesis by theca cells…”
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CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy by Ljungberg, M. Cecilia, Ali, Yousuf O., Zhu, Jie, Wu, Chia-Shan, Oka, Kazuhiro, Zhai, R. Grace, Lu, Hui-Chen

“…Tauopathies, characterized by neurofibrillary tangles (NFTs) of phosphorylated tau proteins, are a group of neurodegenerative diseases, including…”
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Deletion of Porcn in Mice Leads to Multiple Developmental Defects and Models Human Focal Dermal Hypoplasia (Goltz Syndrome) by Liu, Wei, Shaver, Timothy M, Balasa, Alfred, Ljungberg, M. Cecilia, Wang, Xiaoling, Wen, Shu, Nguyen, Hoang, Van den Veyver, Ignatia B, Singh, Shree Ram

“…Focal Dermal Hypoplasia (FDH) is a genetic disorder characterized by developmental defects in skin, skeleton and ectodermal appendages. FDH is caused by…”
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Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia by Ljungberg, M Cecilia, Sunnen, C Nicole, Lugo, Joaquin N, Anderson, Anne E, D'Arcangelo, Gabriella

“…Malformations of the cerebral cortex known as cortical dysplasia account for the majority of cases of intractable childhood epilepsy. With the exception of the…”
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Activation of mammalian target of rapamycin in cytomegalic neurons of human cortical dysplasia by Ljungberg, M. Cecilia, Bhattacharjee, Meenakshi B., Lu, Yaojuan, Armstrong, Dawna L., Yoshor, Daniel, Swann, John W., Sheldon, Michael, D'Arcangelo, Gabriella

“…Objective The cortex of patients with cortical dysplasia contains several abnormal cell types. Among the dysplastic cells, cytomegalic neurons are known to be…”
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Spatial distribution of marker gene activity in the mouse lung during alveolarization by Ljungberg, M. Cecilia, Sadi, Mayce, Wang, Yunguan, Aronow, Bruce J., Xu, Yan, Kao, Rong J., Liu, Ying, Gaddis, Nathan, Ardini-Poleske, Maryanne E., Umrod, Tipparat, Ambalavanan, Namasivayam, Nicola, Teodora, Kaminski, Naftali, Ahangari, Farida, Sontag, Ryan, Corley, Richard A., Ansong, Charles, Carson, James P.

“…This data is a curated collection of visual images of gene expression patterns from the pre- and post-natal mouse lung, accompanied by associated mRNA probe…”
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A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain by Butts, Jessica C, Wu, Sih-Rong, Durham, Mark A, Dhindsa, Ryan S, Revelli, Jean-Pierre, Ljungberg, M Cecilia, Saulnier, Olivier, McLaren, Madison E, Taylor, Michael D, Zoghbi, Huda Y

“…Proneural transcription factors establish molecular cascades to orchestrate neuronal diversity. One such transcription factor, Atonal homolog 1 (Atoh1), gives…”
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A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins by Sakai, Keiko, Tiebel, Oliver, Ljungberg, M. Cecilia, Sullivan, Merry, Lee, Hye-Jeong, Terashima, Tomoya, Li, Rongying, Kobayashi, Kunihisa, Lu, Hui-Chen, Chan, Lawrence, Oka, Kazuhiro

“…Abstract Very-low-density lipoprotein receptor (VLDLR) is a multi ligand apolipoprotein E (apoE) receptor and is involved in brain development through Reelin…”
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SOX7 deficiency causes ventricular septal defects through its effects on endocardial-to-mesenchymal transition and the expression of Wnt4 and Bmp2 by Hernández-García, Andrés, Pendleton, Katherine E, Kim, Sangbae, Li, Yumei, Kim, Bum J, Zaveri, Hitisha P, Jordan, Valerie K, Berry, Aliska M, Ljungberg, M Cecilia, Chen, Rui, Lanz, Rainer B, Scott, Daryl A

“…Abstract SOX7 is a transcription factor-encoding gene located in a region on chromosome 8p23.1 that is recurrently deleted in individuals with ventricular…”
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An oocyte‐specific Cas9‐expressing mouse for germline CRISPR/Cas9‐mediated genome editing by Lanza, Denise G., Mao, Jianqiang, Lorenzo, Isabel, Liao, Lan, Seavitt, John R., Ljungberg, M. Cecilia, Simpson, Elizabeth M., DeMayo, Francesco J., Heaney, Jason D.

“…Summary Cas9 transgenes can be employed for genome editing in mouse zygotes. However, using transgenic instead of exogenous Cas9 to produce gene‐edited animals…”
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Biallelic Variants in OTUD6B Cause an Intellectual Disability Syndrome Associated with Seizures and Dysmorphic Features by Santiago-Sim, Teresa, Burrage, Lindsay C., Ebstein, Frédéric, Tokita, Mari J., Miller, Marcus, Bi, Weimin, Braxton, Alicia A., Rosenfeld, Jill A., Shahrour, Maher, Lehmann, Andrea, Cogné, Benjamin, Küry, Sébastien, Besnard, Thomas, Isidor, Bertrand, Bézieau, Stéphane, Hazart, Isabelle, Nagakura, Honey, Immken, LaDonna L., Littlejohn, Rebecca O., Roeder, Elizabeth, Afawi, Zaid, Balling, Rudi, Barisic, Nina, Baulac, Stéphanie, Craiu, Dana, De Jonghe, Peter, Guerrero-Lopez, Rosa, Guerrini, Renzo, Helbig, Ingo, Hjalgrim, Helle, Jähn, Johanna, Klein, Karl Martin, Leguern, Eric, Lerche, Holger, Marini, Carla, Muhle, Hiltrud, Rosenow, Felix, Serratosa, José, Sterbová, Katalin, Suls, Arvid, Moller, Rikke S., Striano, Pasquale, Weber, Yvonne, Zara, Federico, Kara, Bulent, Hardies, Katia, Weckhuysen, Sarah, May, Patrick, Lemke, Johannes R., Elpeleg, Orly, Abu-Libdeh, Bassam, James, Kiely N., Silhavy, Jennifer L., Issa, Mahmoud Y., Zaki, Maha S., Gleeson, Joseph G., Seavitt, John R., Dickinson, Mary E., Ljungberg, M. Cecilia, Wells, Sara, Johnson, Sara J., Teboul, Lydia, Eng, Christine M., Yang, Yaping, Kloetzel, Peter-Michael, Heaney, Jason D., Walkiewicz, Magdalena A.

“…Ubiquitination is a posttranslational modification that regulates many cellular processes including protein degradation, intracellular trafficking, cell…”
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Multifunctional Activity-Based Protein Profiling of the Developing Lung by Stoddard, Ethan G, Volk, Regan F, Carson, James P, Ljungberg, Cecilia M, Murphree, Taylor A, Smith, Jordan N, Sadler, Natalie C, Shukla, Anil K, Ansong, Charles, Wright, Aaron T

“…Lung diseases and disorders are a leading cause of death among infants. Many of these diseases and disorders are caused by premature birth and underdeveloped…”
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S100a4-Cre–mediated deletion of Ptch1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation by Ren, Yi Athena, Monkkonen, Teresa, Lewis, Michael T., Bernard, Daniel J., Christian, Helen C., Jorgez, Carolina J., Moore, Joshua A., Landua, John D., Chin, Haelee M., Chen, Weiqin, Singh, Swarnima, Kim, Ik Sun, Zhang, Xiang H.F., Xia, Yan, Phillips, Kevin J., MacKay, Harry, Waterland, Robert A., Ljungberg, M. Cecilia, Saha, Pradip K., Hartig, Sean M., Coll, Tatiana Fiordelisio, Richards, JoAnne S.

“…Hormones produced by the anterior pituitary gland regulate an array of important physiological functions, but the causes of pituitary hormone disorders are not…”
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Truncated apoE forms tangle-like structures in a neuronal cell line by Ljungberg, M Cecilia, Dayanandan, Rejith, Asuni, Ayodeji, Rupniak, Tom H, Anderton, Brian H, Lovestone, Simon

“…Apolipoprotein E is the predominant brain lipoprotein and polymorphic variation in the APOE gene the major genetic susceptibly factor for late onset…”
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Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans by Lu, Hsiang-Chih, Tan, Qiumin, Rousseaux, Maxime W C, Wang, Wei, Kim, Ji-Yoen, Richman, Ronald, Wan, Ying-Wooi, Yeh, Szu-Ying, Patel, Jay M, Liu, Xiuyun, Lin, Tao, Lee, Yoontae, Fryer, John D, Han, Jing, Chahrour, Maria, Finnell, Richard H, Lei, Yunping, Zurita-Jimenez, Maria E, Ahimaz, Priyanka, Anyane-Yeboa, Kwame, Van Maldergem, Lionel, Lehalle, Daphne, Jean-Marcais, Nolwenn, Mosca-Boidron, Anne-Laure, Thevenon, Julien, Cousin, Margot A, Bro, Della E, Lanpher, Brendan C, Klee, Eric W, Alexander, Nora, Bainbridge, Matthew N, Orr, Harry T, Sillitoe, Roy V, Ljungberg, M Cecilia, Liu, Zhandong, Schaaf, Christian P, Zoghbi, Huda Y

“…Huda Zoghbi and colleagues report that loss of the ATXN1–CIC protein complex in the developing mouse forebrain results in hyperactivity and defects in learning…”
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S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation by Ren, Yi Athena, Monkkonen, Teresa, Lewis, Michael T, Bernard, Daniel J, Christian, Helen C, Jorgez, Carolina J, Moore, Joshua A, Landua, John D, Chin, Haelee M, Chen, Weiqin, Singh, Swarnima, Kim, Ik Sun, Zhang, Xiang Hf, Xia, Yan, Phillips, Kevin J, MacKay, Harry, Waterland, Robert A, Ljungberg, M Cecilia, Saha, Pradip K, Hartig, Sean M, Coll, Tatiana Fiordelisio, Richards, JoAnne S

“…Hormones produced by the anterior pituitary gland regulate an array of important physiological functions, but pituitary hormone disorders are not fully…”
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Monitoring the intracellular fate of apolipoprotein E: Implications for Alzheimer's disease by Ljungberg, Cecilia M., Dayanandan, Rejith, Pearce, Janice, Anderton, Brian H., Lovestone, Simon

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Survival of genetically engineered, adult-derived rat astrocytes grafted into the 6-hydroxydopamine lesioned adult rat striatum by Ljungberg, M.Cecilia, Stern, Gerald, Wilkin, Graham P.

“…Astrocytes are potentially useful as vehicles for gene transfer into the CNS. As endogenous CNS cells, they possess secretory mechanisms and can be grown in…”
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