Search Results - "Ljungberg, Karl"

Intradermal electroporation of naked replicon RNA elicits strong immune responses by Johansson, Daniel X, Ljungberg, Karl, Kakoulidou, Maria, Liljeström, Peter

“…RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery…”
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H1N1 influenza virus induces narcolepsy-like sleep disruption and targets sleep–wake regulatory neurons in mice by Tesoriero, Chiara, Codita, Alina, Zhang, Ming-Dong, Cherninsky, Andrij, Karlsson, Håkan, Grassi-Zucconi, Gigliola, Bertini, Giuseppe, Harkany, Tibor, Ljungberg, Karl, Liljeström, Peter, Hökfelt, Tomas G. M., Bentivoglio, Marina, Kristensson, Krister

“…An increased incidence in the sleep-disorder narcolepsy has been associated with the 2009–2010 pandemic of H1N1 influenza virus in China and with mass…”
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DNA Vaccine Development at Pre- and Post-Operation Warp Speed by Ljungberg, Karl, Isaguliants, Maria

“…DNA is a rapidly developing vaccine platform for combatting cancer, infectious and noninfectious diseases [...]…”
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Alphavirus replicon DNA expressing HIV antigens is an excellent prime for boosting with recombinant modified vaccinia Ankara (MVA) or with HIV gp140 protein antigen by Knudsen, Maria L, Ljungberg, Karl, Tatoud, Roger, Weber, Jonathan, Esteban, Mariano, Liljeström, Peter

“…Vaccination with DNA is an attractive strategy for induction of pathogen-specific T cells and antibodies. Studies in humans have shown that DNA vaccines are…”
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Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens by van de Wall, Stephanie, Ljungberg, Karl, Ip, Peng Peng, Boerma, Annemarie, Knudsen, Maria L., Nijman, Hans W., Liljeström, Peter, Daemen, Toos

“…Cervical cancer develops as a result of infection with high-risk human papillomavirus (HPV) through persistent expression of early proteins E6 and E7. Our…”
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Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus by Roques, Pierre, Ljungberg, Karl, Kümmerer, Beate M, Gosse, Leslie, Dereuddre-Bosquet, Nathalie, Tchitchek, Nicolas, Hallengärd, David, García-Arriaza, Juan, Meinke, Andreas, Esteban, Mariano, Merits, Andres, Le Grand, Roger, Liljeström, Peter

“…Chikungunya virus (CHIKV) is rapidly spreading across the globe, and millions are infected. Morbidity due to this virus is a serious threat to public health,…”
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Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine by KNUDSEN, Maria L, MBEWE-MVULA, Alice, LILJESTRÖM, Peter, ROSARIO, Maximillian, JOHANSSON, Daniel X, KAKOULIDOU, Maria, BRIDGEMAN, Anne, REYES-SANDOVAL, Arturo, NICOSIA, Alfredo, LJUNGBERG, Karl, HANKE, Tomáš

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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The adjuvant activity of alphavirus replicons is enhanced by incorporating the microbial molecule flagellin into the replicon by Knudsen, Maria L, Johansson, Daniel X, Kostic, Linda, Nordström, Eva K L, Tegerstedt, Karin, Pasetto, Anna, Applequist, Steven E, Ljungberg, Karl, Sirard, Jean-Claude, Liljeström, Peter

“…Ligands of pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) stimulate innate and adaptive immune responses and are considered as…”
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Host gene expression signatures discriminate between ferrets infected with genetically similar H1N1 strains by Ljungberg, Karl, McBrayer, Alexis, Camp, Jeremy V, Chu, Yong-Kyu, Tapp, Ronald, Noah, Diana L, Grimes, Sheila, Proctor, Mary L, Liljeström, Peter, Jonsson, Colleen B, Bruder, Carl E

“…Different respiratory viruses induce virus-specific gene expression in the host. Recent evidence, including those presented here, suggests that genetically…”
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Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine by LJUNGBERG, Karl, WHITMORE, Alan C, JOHNSTON, Robert E, FLUET, Meagan E, MORAN, Timothy P, SHABMAN, Reed S, COLLIER, Martha L, KRAUS, Annette A, THOMPSON, Joseph M, MONTEFIORI, David C, BEARD, Clayton

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multilaboratory Comparison of Pneumococcal Multiplex Immunoassays Used in Immunosurveillance of Streptococcus pneumoniae across Europe by Meek, Bob, Ekström, Nina, Kantsø, Bjørn, Almond, Rachael, Findlow, Jamie, Gritzfeld, Jenna F, Sværke Jørgensen, Charlotte, Ljungberg, Karl, Atterfelt, Fredrik, Batstra, Manou R, Andeweg, Kevin, de Jong, Ben A W, Prince, Harry E, Lapé-Nixon, Mary, Gageldonk, Pieter G M, Tcherniaeva, Irina, Aaberge, Ingeborg, Herstad, Tove Karin, Melin, Merit, Rijkers, Ger T, Berbers, Guy A

“…Surveillance studies are required to estimate the impact of pneumococcal vaccination in both children and the elderly across Europe. The World Health…”
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Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication by Elmén, Joacim, Zhang, Hong-Yan, Zuber, Bartek, Ljungberg, Karl, Wahren, Britta, Wahlestedt, Claes, Liang, Zicai

“…We have evaluated antisense design and efficacy of locked nucleic acid (LNA) and DNA oligonucleotide (ON) mix-mers targeting the conserved HIV-1 dimerization…”
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Immunotherapy with an HIV-DNA Vaccine in Children and Adults by Palma, Paolo, Gudmundsdotter, Lindvi, Finocchi, Andrea, Eriksson, Lars E, Mora, Nadia, Santilli, Veronica, Aquilani, Angela, Manno, Emma C, Zangari, Paola, Romiti, Maria Luisa, Montesano, Carla, Grifoni, Alba, Brave, Andreas, Ljungberg, Karl, Blomberg, Pontus, Bernardi, Stefania, Sandström, Eric, Hejdeman, Bo, Rossi, Paolo, Wahren, Britta

“…Therapeutic HIV immunization is intended to induce new HIV-specific cellular immune responses and to reduce viral load, possibly permitting extended periods…”
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Self-replicating alphavirus RNA vaccines by Ljungberg, Karl, Liljeström, Peter

“…Recombinant nucleic acids are considered as promising next-generation vaccines. These vaccines express the native antigen upon delivery into tissue, thus…”
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Distinct Immunogenicity and Efficacy of Poxvirus-Based Vaccine Candidates against Ebola Virus Expressing GP and VP40 Proteins by Lázaro-Frías, Adrián, Gómez-Medina, Sergio, Sánchez-Sampedro, Lucas, Ljungberg, Karl, Ustav, Mart, Liljeström, Peter, Muñoz-Fontela, César, Esteban, Mariano, García-Arriaza, Juan

“…and species cause a severe disease in humans and nonhuman primates (NHPs) characterized by a high mortality rate. There are no licensed therapies or vaccines…”
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Infectious RNA vaccine protects mice against chikungunya virus infection by Szurgot, Inga, Ljungberg, Karl, Kümmerer, Beate M., Liljeström, Peter

“…We describe a novel vaccine platform that can generate protective immunity to chikungunya virus (CHIKV) in C57BL/6J mice after a single immunization by…”
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Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality by Elmén, Joacim, Thonberg, Håkan, Ljungberg, Karl, Frieden, Miriam, Westergaard, Majken, Xu, Yunhe, Wahren, Britta, Liang, Zicai, Ørum, Henrik, Koch, Troels, Wahlestedt, Claes

“…Therapeutic application of the recently discovered small interfering RNA (siRNA) gene silencing phenomenon will be dependent on improvements in molecule…”
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DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boost by Öhlund, Pontus, García-Arriaza, Juan, Zusinaite, Eva, Szurgot, Inga, Männik, Andres, Kraus, Annette, Ustav, Mart, Merits, Andres, Esteban, Mariano, Liljeström, Peter, Ljungberg, Karl

“…There are currently no licensed therapeutic treatment or preventive vaccines against Ebolavirus disease, and the 2013–2016 West African outbreak of Ebolavirus…”
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Potent Anti-hepatitis C Virus (HCV) T Cell Immune Responses Induced in Mice Vaccinated with DNA-Launched RNA Replicons and Modified Vaccinia Virus Ankara-HCV by Marín, María Q, Pérez, Patricia, Ljungberg, Karl, Sorzano, Carlos Óscar S, Gómez, Carmen E, Liljeström, Peter, Esteban, Mariano, García-Arriaza, Juan

“…Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) affecting 71 million people worldwide with no licensed vaccines that prevent infection…”
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Alphavirus Replicon DNA Expressing HIV Antigens Is an Excellent Prime for Boosting with Recombinant Modified Vaccinia Ankara by Knudsen, Maria L, Ljungberg, Karl, Tatoud, Roger, Weber, Jonathan, Esteban, Mariano, Liljeström, Peter

“…Vaccination with DNA is an attractive strategy for induction of pathogen-specific T cells and antibodies. Studies in humans have shown that DNA vaccines are…”
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