Search Results - "Ljubicic, Marie Lindhardt"
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Longitudinal Increases in Serum Insulin-like Factor 3 and Testosterone Determined by LC-MS/MS in Pubertal Danish Boys
Published in The journal of clinical endocrinology and metabolism (01-10-2020)“…Serum concentrations of the peptide hormone insulin-like factor 3 (INSL3) is a candidate marker for improved distinction between constitutional delay of growth…”
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Dynamic Changes of Reproductive Hormones in Male Minipuberty: Temporal Dissociation of Leydig and Sertoli Cell Activity
Published in The journal of clinical endocrinology and metabolism (01-06-2022)“…The male hypothalamic-pituitary-gonadal (HPG) axis is transiently active during the first months of life with surging serum concentrations of reproductive…”
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Sex Differences in Reproductive Hormones During Mini-Puberty in Infants With Normal and Disordered Sex Development
Published in The journal of clinical endocrinology and metabolism (01-08-2018)“…Abstract Context The early activation of the hypothalamic-pituitary-gonadal axis during infancy can be used in the evaluation of infants suspected of disorders…”
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Polygenic Scores for Adult Testosterone and SHBG Levels Are Associated With Reproductive Hormone Levels in Male Infants
Published in The journal of clinical endocrinology and metabolism (13-08-2024)“…Abstract Context The hypothalamic-pituitary-gonadal axis's transient activity in infancy, i.e, minipuberty, is considered crucial for male reproductive…”
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Exposure to 15 phthalates and two substitutes (DEHTP and DINCH) assessed in trios of infants and their parents as well as longitudinally in infants exclusively breastfed and after the introduction of a mixed diet
Published in Environment international (01-03-2022)“…[Display omitted] •Metabolites of 15 phthalates and the two substitutes DEHTP and DINCH were analyzed in urine from Danish infants and their…”
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Anogenital Distance in Healthy Infants: Method-, Age- and Sex-related Reference Ranges
Published in The journal of clinical endocrinology and metabolism (01-09-2020)“…Abstract Context The use of anogenital distance (AGD) in clinical and epidemiological settings is increasing; however, sex-specific reference data on AGD and…”
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The External Genitalia Score (EGS): A European Multicenter Validation Study
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Context Standardized description of external genitalia is needed in the assessment of children with atypical genitalia. Objectives To validate the…”
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Benzophenones, bisphenols and other polychlorinated/phenolic substances in Danish infants and their parents – including longitudinal assessments before and after introduction to mixed diet
Published in Environment international (01-11-2022)“…[Display omitted] •Urinary concentrations of 12 out of 22 benzophenones, bisphenols and other phenols were observed in healthy Danish infants and their…”
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Clinical but Not Histological Outcomes in Males With 45,X/46,XY Mosaicism Vary Depending on Reason for Diagnosis
Published in The journal of clinical endocrinology and metabolism (01-10-2019)“…Abstract Context Larger studies on outcomes in males with 45,X/46,XY mosaicism are rare. Objective To compare health outcomes in males with 45,X/46,XY…”
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Cohort profile: The COPENHAGEN Minipuberty Study—A longitudinal prospective cohort of healthy full‐term infants and their parents
Published in Paediatric and perinatal epidemiology (01-09-2021)“…Background The hypothalamic‐pituitary‐gonadal (HPG) axis governs sexual maturation and reproductive function in humans. In early postnatal life, it is…”
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The Application of Principal Component Analysis on Clinical and Biochemical Parameters Exemplified in Children With Congenital Adrenal Hyperplasia
Published in Frontiers in endocrinology (Lausanne) (31-08-2021)“…Principal component analysis (PCA) is a mathematical model which simplifies data into new, combined variables. Optimal treatment of pediatric congenital…”
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Longitudinal evaluation of breast tissue in healthy infants: Prevalence and relation to reproductive hormones and growth factors
Published in Frontiers in endocrinology (Lausanne) (01-12-2022)“…Breast tissue in infancy is a rather undescribed phenomenon. We aimed to describe the prevalence and progression of palpable breast tissue in healthy boys and…”
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Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism
Published in Frontiers in endocrinology (Lausanne) (10-08-2021)“…Insulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in…”
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Reduced serum concentrations of biomarkers reflecting Leydig and Sertoli cell function in male patients with congenital adrenal hyperplasia
Published in Endocrine Connections (14-07-2023)“…Congenital adrenal hyperplasia (CAH) is a recessive condition that affects the adrenal glands. Despite life-long replacement therapy with glucocorticoids and…”
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Serum LH/FSH ratios in 87 infants with differences of sex development
Published in Endocrine Connections (01-03-2023)“…The ratio between luteinizing hormone (LH) and follicle-stimulating hormone (FSH) has previously been described as an excellent marker of sex in healthy…”
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Distinguishing between hidden testes and anorchia: the role of endocrine evaluation in infancy and childhood
Published in European journal of endocrinology (01-07-2020)“…Objective Non-palpable testes remain a diagnostic challenge, often involving exploratory laparoscopy. We evaluated the diagnostic value of a wide range of…”
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Serum Concentrations of Inhibin B in Healthy Females and Males Throughout Life
Published in The journal of clinical endocrinology and metabolism (26-06-2024)“…To describe the natural history of inhibin B throughout life according to sex, age, and pubertal development. Based on serum samples from 2707 healthy controls…”
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Dynamic changes in LH/FSH ratios in infants with normal sex development
Published in European journal of endocrinology (01-07-2022)“…Objective Little is known about the ratio between luteinizing hormone (LH) and follicle-stimulating hormone (FSH) during infancy. This study aimed to evaluate…”
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Reference Curves for Pediatric Endocrinology: Leveraging Biomarker Z-Scores for Clinical Classifications
Published in The journal of clinical endocrinology and metabolism (16-06-2022)“…Hormone reference intervals in pediatric endocrinology are traditionally partitioned by age and lack the framework for benchmarking individual blood test…”
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