Search Results - "Lizard, G."

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy by Raas, Q., Gondcaille, C., Hamon, Y., Leoni, V., Caccia, C., Ménétrier, F., Lizard, G., Trompier, D., Savary, S.

“…X-linked adrenoleukodystrophy (X-ALD), the most frequent peroxisomal disorder, is associated with mutation in the ABCD1 gene which encodes a peroxisomal…”
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Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis by Vejux, A, Malvitte, L, Lizard, G

“…Oxysterols are 27-carbon atom molecules resulting from autoxidation or enzymatic oxidation of cholesterol. They are present in numerous foodstuffs and have…”
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Cellular interactions of functionalized superparamagnetic iron oxide nanoparticles on oligodendrocytes without detrimental side effects: Cell death induction, oxidative stress and inflammation by Sruthi, S., Maurizi, L., Nury, T., Sallem, F., Boudon, J., Riedinger, J.M., Millot, N., Bouyer, F., Lizard, G.

“…[Display omitted] •SPIONs functionalized with PEG and rhodamine with oligodendrocytes.•Dose effect and a maximum SPIONs loading on cells.•No toxicological and…”
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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases by Nury, T., Yammine, A., Ghzaiel, I., Sassi, K., Zarrouk, A., Brahmi, F., Samadi, M., Rup-Jacques, S., Vervandier-Fasseur, D., Pais de Barros, J.P., Bergas, V., Ghosh, S., Majeed, M., Pande, A., Atanasov, A., Hammami, S., Hammami, M., Mackrill, J., Nasser, B., Andreoletti, P., Cherkaoui-Malki, M., Vejux, A., Lizard, G.

“…[Display omitted] •7-ketocholesterol and 7β-hydroxycholesterol are increased in several age-related diseases.•7-ketocholesterol and 7β-hydroxycholesterol…”
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A microglial cell model for acyl-CoA oxidase 1 deficiency by Raas, Q., Saih, F.-E., Gondcaille, C., Trompier, D., Hamon, Y., Leoni, V., Caccia, C., Nasser, B., Jadot, M., Ménétrier, F., Lizard, G., Cherkaoui-Malki, M., Andreoletti, P., Savary, S.

“…Acyl-CoA oxidase 1 (ACOX1) deficiency is a rare and severe peroxisomal leukodystrophy associated with a very long-chain fatty acid (VLCFA) β–oxidation defect…”
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Evidence of oxidative stress in very long chain fatty acid – Treated oligodendrocytes and potentialization of ROS production using RNA interference-directed knockdown of ABCD1 and ACOX1 peroxisomal proteins by Baarine, M, Andréoletti, P, Athias, A, Nury, T, Zarrouk, A, Ragot, K, Vejux, A, Riedinger, J.-M, Kattan, Z, Bessede, G, Trompier, D, Savary, S, Cherkaoui-Malki, M, Lizard, G

“…Graphical abstract Murine oligodendrocytes (158N) transfected with scrambled (Scr) siRNA or with siRNA against Abcd1 or Acox1 were further cultured for 24 h in…”
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Brain peroxisomes by Trompier, D., Vejux, A., Zarrouk, A., Gondcaille, C., Geillon, F., Nury, T., Savary, S., Lizard, G.

“…Peroxisomes are essential organelles in higher eukaryotes as they play a major role in numerous metabolic pathways and redox homeostasis. Some peroxisomal…”
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In vitro interaction and biocompatibility of titanate nanotubes with microglial cells by Sruthi, S., Loiseau, A., Boudon, J., Sallem, F., Maurizi, L., Mohanan, P.V., Lizard, G., Millot, N.

“…Titanate nanotubes (TiONts) are promising agents for biomedical applications. Microglial activation and associated oxidative burst are major challenges in drug…”
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Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells by Sassi, K., Nury, T., Zarrouk, A., Sghaier, R., Khalafi-Nezhad, A., Vejux, A., Samadi, M., Aissa-Fennira, F. Ben, Lizard, G.

“…[Display omitted] •Steroidal maleic anhydrides, lithocholic and chenodeoxicholic acid derivatives, and 7β-hydroxycholesterol (positive control) have a high…”
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The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models by Colin, D J, Limagne, E, Ragot, K, Lizard, G, Ghiringhelli, F, Solary, É, Chauffert, B, Latruffe, N, Delmas, D

“…In spite of the novel strategies to treat colon cancer, mortality rates associated with this disease remain consistently high. Tumour recurrence has been…”
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Oxysterols and sterols: From lipidomics to food sciences by Rodriguez-Estrada, M.T., Cardenia, V., Poirot, M., Iuliano, L., Lizard, G.

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Neurodegeneration, oxidative stress and lipid metabolism plasma biomarkers to differentiate Parkinson's disease from atypical parkinsonian syndromes by Schneider, V., Vejux, A., Nury, T., Dupont, G., Pais de Barros, J.P., Lakomy, D., Lizard, G., Moreau, T.

“…•Differentiating PD from APS remains challenging.•Blood biomarkers appear to be a means of improving diagnosis accuracy in PD and APS.•Plasma levels of NFL,…”
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Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols by Lemaire-Ewing, S, Prunet, C, Montange, T, Vejux, A, Berthier, A, Bessède, G, Corcos, L, Gambert, P, Néel, D, Lizard, G

“…Oxidized low-density lipoproteins play important roles in the development of atherosclerosis and contain several lipid-derived, bioactive molecules which are…”
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Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): Argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity by Zarrouk, A., Hammami, M., Moreau, T., Lizard, G.

“…Cholesterol oxide derivatives (oxysterols) are viewed as potential biomarkers of neurodegenerative diseases. 24S-hydroxycholesterol, an oxysterol produced only…”
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The Inflammatory Response in Acyl-CoA Oxidase 1 Deficiency (Pseudoneonatal Adrenoleukodystrophy) by El Hajj, H. I, Vluggens, A, Andreoletti, P, Ragot, K, Mandard, S, Kersten, S, Waterham, H. R, Lizard, G, Wanders, R. J. A, Reddy, J. K, Cherkaoui-Malki, Mustapha

“…Among several peroxisomal neurodegenerative disorders, the pseudoneonatal adrenoleukodystrophy (P-NALD) is characterized by the acyl-coenzyme A oxidase 1…”
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Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs by Malvitte, L, Montange, T, Vejux, A, Baudouin, C, Bron, A M, Creuzot-Garcher, C, Lizard, G

“…Aim: To investigate the ocular surface inflammatory response to chronic topical treatments in patients with glaucoma by measuring the cytokine level in tears…”
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Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis by Berthier, A, Lemaire-Ewing, S, Prunet, C, Monier, S, Athias, A, Bessède, G, Pais de Barros, J-P, Laubriet, A, Gambert, P, Lizard, G, Néel, D

“…7-Ketocholesterol is a component of oxidized LDL, which plays a central role in atherosclerosis. It is a potent inducer of cell death towards a wide number of…”
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Dual effect of docosahexaenoic acid (attenuation or amplification) on C22:0-, C24:0-, and C26:0-Induced mitochondrial dysfunctions and oxidative stress on human neuronal SK-N-BE cells by Zarrouk, A., Nury, T., Riedinger, J. M., Rouaud, O., Hammami, M., Lizard, Gérard

“…Increased levels of C22:0, C24:0 and C26:0 were found in cortical lesions of patients with Alzheimer’s disease (AD). So, it was of interest to precise the…”
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Protective effects of bezafibrate against elaidic acid-induced accumulation of lipid droplets in monocytic cells by Haj Ahmed, S., Kharroubi, W., Zarrouk, A., Brahmi, F., Nury, T., Lizard, G., Hammami, M.

“…Some factors related to diet, such as trans fatty acids (TFA), are known to be involved in the progression of atherosclerosis in humans. Thus, the aim of our…”
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Determination of heavy metal content and lipid profiles in mussel extracts from two sites on the moroccan atlantic coast and evaluation of their biological activities on MIN6 pancreatic cells by Boumhras, M, Ouafik, S, Nury, T, Gresti, J, Athias, A, Ragot, K, Nasser, B, Cherkaoui‐Malki, M, Lizard, G

“…Mussels may concentrate pollutants, with possibly significant side effects on human health. Therefore, mussels (Mytilus galloprovincialis) from two sites of…”
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