Search Results - "Lizak, Martin"

ISMRM Raw data format: A proposed standard for MRI raw datasets by Inati, Souheil J., Naegele, Joseph D., Zwart, Nicholas R., Roopchansingh, Vinai, Lizak, Martin J., Hansen, David C., Liu, Chia‐Ying, Atkinson, David, Kellman, Peter, Kozerke, Sebastian, Xue, Hui, Campbell‐Washburn, Adrienne E., Sørensen, Thomas S., Hansen, Michael S.

“…Purpose This work proposes the ISMRM Raw Data format as a common MR raw data format, which promotes algorithm and data sharing. Methods A file format…”
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Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms by Mukhopadhyay, Bani, Schuebel, Kornel, Mukhopadhyay, Partha, Cinar, Resat, Godlewski, Grzegorz, Xiong, Keming, Mackie, Ken, Lizak, Martin, Yuan, Qiaoping, Goldman, David, Kunos, George

“…Hepatocellular carcinoma (HCC) has high mortality and no adequate treatment. Endocannabinoids interact with hepatic cannabinoid 1 receptors (CB1Rs) to promote…”
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Diffusion tensor and volumetric magnetic resonance measures as biomarkers of brain damage in a small animal model of HIV by Lentz, Margaret R, Peterson, Kristin L, Ibrahim, Wael G, Lee, Dianne E, Sarlls, Joelle, Lizak, Martin J, Maric, Dragan, Reid, William C, Hammoud, Dima A

“…There are currently no widely accepted neuro-HIV small animal models. We wanted to validate the HIV-1 Transgenic rat (Tg) as an appropriate neuro-HIV model and…”
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Amphotericin B Penetrates into the Central Nervous System Through Focal Disruption of the Blood Brain Barrier in Experimental Hematogenous Candida Meningoencephalitis by Petraitis, Vidmantas, Petraitiene, Ruta, Valdez, Jessica M, Pyrgos, Vasilios, Lizak, Martin J, Klaunberg, Brenda A, Kalasauskas, Darius, Basevicius, Algidas, Bacher, John D, Benjamin, Jr, Daniel K, Hope, William W, Walsh, Thomas J

“…Hematogenous meningoencephalitis (HCME) is a life-threatening complication of neonates and immunocompromised children. Amphotericin B (AmB) shows poor…”
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Urea amidolyase (DUR1,2) contributes to virulence and kidney pathogenesis of Candida albicans by Navarathna, Dhammika H M L P, Lionakis, Michail S, Lizak, Martin J, Munasinghe, Jeeva, Nickerson, Kenneth W, Roberts, David D

“…The intracellular enzyme urea amidolyase (Dur1,2p) enables C. albicans to utilize urea as a sole nitrogen source. Because deletion of the DUR1,2 gene reduces…”
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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model by Lim, Sanghee, Kwak, Minhye, Kang, Jeonghan, Cesaire, Melissa, Tang, Kayen, Robey, Robert W, Frye, William J E, Karim, Baktiar, Butcher, Donna, Lizak, Martin J, Dalmage, Mahalia, Foster, Brandon, Nuechterlein, Nicholas, Eberhart, Charles, Cimino, Patrick J, Gottesman, Michael M, Jackson, Sadhana

“…In malignant glioma, cytotoxic drugs are often inhibited from accessing the tumor site due to the blood-tumor barrier (BTB). Ibrutinib, FDA-approved lymphoma…”
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In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization by Matsumoto, Shingo, Saito, Keita, Takakusagi, Yoichi, Matsuo, Masayuki, Munasinghe, Jeeva P, Morris, Herman D, Lizak, Martin J, Merkle, Hellmut, Yasukawa, Keiji, Devasahayam, Nallathamby, Suburamanian, Sankaran, Mitchell, James B, Krishna, Murali C

“…The tumor microenvironment is characterized by a highly reducing redox status, a low pH, and hypoxia. Anti-angiogenic therapies for solid tumors frequently…”
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Imaging Candida Infections in the Host by Navarathna, Dhammika H, Roberts, David D, Munasinghe, Jeeva, Lizak, Martin J

“…Disseminated fungal infections caused by Candida species are associated with homing of the pathogen to specific organs in human and murine hosts. Kidneys are a…”
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ADP-Ribosylarginine Hydrolase Regulates Cell Proliferation and Tumorigenesis by KATO, Jiro, JIANFENG ZHU, CHENGYU LIU, STYLIANOU, Mario, HOFFMANN, Victoria, LIZAK, Martin J, GLASGOW, Connie G, MOSS, Joel

“…Protein ADP-ribosylation is a reversible posttranslational modification of uncertain significance in cancer. In this study, we evaluated the consequences for…”
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Pore diameter mapping using double pulsed-field gradient MRI and its validation using a novel glass capillary array phantom by Komlosh, Michal E., Özarslan, Evren, Lizak, Martin J., Horkay, Ferenc, Schram, Vincent, Shemesh, Noam, Cohen, Yoram, Basser, Peter J.

“…Novel glass capillary array phantom: Photographic and optical microscope images of a dry water, d-PFG MRI of the constructed phantom, and the corresponding…”
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EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models by Venugopalan, Abhilash, Lee, Min-Jung, Niu, Gang, Medina-Echeverz, José, Tomita, Yusuke, Lizak, Martin J, Cultraro, Constance M, Simpson, Robert Mark, Chen, Xiaoyuan, Trepel, Jane B, Guha, Udayan

“…Lung adenocarcinoma patients harboring kinase domain mutations in Epidermal growth factor receptor (EGFR) have significant clinical benefit from EGFR-targeted…”
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PP2A inhibition with LB100 enhances cisplatin cytotoxicity and overcomes cisplatin resistance in medulloblastoma cells by Ho, Winson S, Feldman, Michael J, Maric, Dragan, Amable, Lauren, Hall, Matthew D, Feldman, Gerald M, Ray-Chaudhury, Abhik, Lizak, Martin J, Vera, Juan-Carlos, Robison, R Aaron, Zhuang, Zhengping, Heiss, John D

“…The protein phosphatase 2A (PP2A) inhibitor, LB100, has been shown in pre-clinical studies to be an effective chemo- and radio-sensitizer for treatment of…”
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MR assessment of changes of tumor in response to hyperbaric oxygen treatment by Matsumoto, Ken-ichiro, Bernardo, Marcelino, Subramanian, Sankaran, Choyke, Peter, Mitchell, James B., Krishna, Murali C., Lizak, Martin J.

“…Enhancement of image intensity, using the T1‐weighted spoiled gradient‐echo (SPGR) sequence, was measured in SCC tumor implanted in the flank of C3H mice while…”
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MRI confirms loss of blood-brain barrier integrity in a mouse model of disseminated candidiasis by Navarathna, Dhammika H. M. L. P., Munasinghe, Jeeva, Lizak, Martin J., Nayak, Debasis, McGavern, Dorian B., Roberts, David D.

“…Disseminated candidiasis primarily targets the kidneys and brain in mice and humans. Damage to these critical organs leads to the high mortality associated…”
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MRI in ocular drug delivery by Li, S. Kevin, J. Lizak, Martin, Jeong, Eun-Kee

“…Conventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI…”
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Transient decrease in tumor oxygenation after intravenous administration of pyruvate by Saito, Keita, Matsumoto, Shingo, Devasahayam, Nallathamby, Subramanian, Sankaran, Munasinghe, Jeeva P., Morris, H. Douglas, Lizak, Martin J., Ardenkjaer-Larsen, Jan Henrik, Mitchell, James B., Krishna, Murali C.

“…MRI using hyperpolarized 13C‐labeled pyruvate is a promising tool to biochemically profile tumors and monitor their response to therapy. This technique…”
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Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging by Giubellino, Alessio, Woldemichael, Girma M, Sourbier, Carole, Lizak, Martin J, Powers, James F, Tischler, Arthur S, Pacak, Karel

“…Abstract Pheochromocytoma is the most common tumor of the adrenal medulla in adults. The lack of sensitive animal models of pheochromocytoma has hindered the…”
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Controlled Drug Release from an Ocular Implant: An Evaluation Using Dynamic Three-Dimensional Magnetic Resonance Imaging by Kim, Hyuncheol, Robinson, Michael R, Lizak, Martin J, Tansey, Ginger, Lutz, Robert J, Yuan, Peng, Wang, Nam S, Csaky, Karl G

“…The ability of an episcleral implant at the equator of the eye to deliver drugs to the posterior segment was evaluated, using a sustained-release implant…”
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13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors by Saito, Keita, Matsumoto, Shingo, Takakusagi, Yoichi, Matsuo, Masayuki, Morris, H Douglas, Lizak, Martin J, Munasinghe, Jeeva P, Devasahayam, Nallathamby, Subramanian, Sankaran, Mitchell, James B, Krishna, Murali C

“…X-ray irradiation of tumors causes diverse effects on the tumor microenvironment, including metabolism. Recent developments of hyperpolarized (13)C-MRI enabled…”
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Assessment of Subconjunctival and Intrascleral Drug Delivery to the Posterior Segment Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging by Kim, Stephanie H, Galban, Craig J, Lutz, Robert J, Dedrick, Robert L, Csaky, Karl G, Lizak, Martin J, Wang, Nam Sun, Tansey, Ginger, Robinson, Michael R

“…Sustained-release intravitreal drug implants for posterior segment diseases are associated with significant complications. As an alternative, subconjunctival…”
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