Search Results - "Lizárraga, Daneida"
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The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism
Published in BMC cancer (27-04-2011)“…Maslinic acid, a pentacyclic triterpene found in the protective wax-like coating of the leaves and fruit of Olea europaea L., is a promising agent for the…”
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Grape antioxidant dietary fiber inhibits intestinal polyposis in ApcMin/+ mice: relation to cell cycle and immune response
Published in Carcinogenesis (New York) (01-08-2013)“…Epidemiological and experimental studies suggest that fiber and phenolic compounds might have a protective effect on the development of colon cancer in humans…”
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Highly Galloylated Tannin Fractions from Witch Hazel (Hamamelis virginiana) Bark: Electron Transfer Capacity, In Vitro Antioxidant Activity, and Effects on Skin-Related Cells
Published in Chemical research in toxicology (01-03-2008)“…Witch hazel (Hammamelis virginiana) bark is a rich source of both condensed and hydrolizable oligomeric tannins. From a polyphenolic extract soluble in both…”
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Witch Hazel (Hamamelis virginiana) Fractions and the Importance of Gallate MoietiesElectron Transfer Capacities in Their Antitumoral Properties
Published in Journal of agricultural and food chemistry (24-12-2008)“…Witch hazel (Hamamelis virginia) extracts are used in traditional medicine. They are particularly rich in gallate esters included in proanthocyanidins,…”
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Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes
Published in Toxicology in vitro (01-09-2011)“…► The effect of TSA was investigated on microRNA in primary rat hepatocytes. ► miR-21 and miR-126 are related to the proliferative response upon cultivation. ►…”
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Procyanidin Fractions from Pine (Pinus pinaster) Bark: Radical Scavenging Power in Solution, Antioxidant Activity in Emulsion, and Antiproliferative Effect in Melanoma Cells
Published in Journal of agricultural and food chemistry (15-06-2005)“…Pine (Pinus pinaster) bark is a rich source of procyanidin oligomers. From a total polyphenolic extract, we have generated fractions of different procyanidin…”
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Grape antioxidant dietary fiber inhibits intestinal polyposis in Apc Min/+ mice: relation to cell cycle and immune response
Published in Carcinogenesis (New York) (01-08-2013)Get full text
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Age-Related Differences in miRNA Expression in Mexican-American Newborns and Children
Published in International journal of environmental research and public health (13-02-2019)“…Epigenetic mechanisms have emerged as an important pathway through which environmental exposures can affect health through the regulation of gene expression…”
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Recent progress in the genetics and epigenetics of paraoxonase: why it is relevant to children's environmental health
Published in Current opinion in pediatrics (01-04-2015)“…Children are more susceptible to exposures in utero and during early childhood that may result in developmental problems and chronic diseases. Novel…”
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miRNAs differentially expressed by next-generation sequencing in cord blood buffy coat samples of boys and girls
Published in Epigenomics (01-12-2016)“…Differences in children's development and susceptibility to diseases and exposures have been observed by sex, yet human studies of sex differences in miRNAs…”
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RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene
Published in Toxicological sciences (01-12-2012)“…Whole-genome transcriptome measurements are pivotal for characterizing molecular mechanisms of chemicals and predicting toxic classes, such as genotoxicity and…”
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Benzo[a]pyrene-Induced Changes in MicroRNA–mRNA Networks
Published in Chemical research in toxicology (16-04-2012)“…Toxicological studies assessing the safety of compounds for humans frequently use in vitro systems to characterize toxic responses in combination with…”
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A lyophilized red grape pomace containing proanthocyanidin-rich dietary fiber induces genetic and metabolic alterations in colon mucosa of female C57BL/6J mice
Published in The Journal of nutrition (01-09-2011)“…Diet plays a decisive role in promoting or preventing colon cancer. However, the specific effects of some nutrients remain unclear. The capacity of fruit and…”
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Predicting in vivo genotoxicity using mRNA and miRNA data from two in vitro liver models
Published in Toxicology letters (28-08-2013)Get full text
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Grape antioxidant dietary fiber inhibits intestinal polyposis in Apc super(Min/+) mice: relation to cell cycle and immune response
Published in Carcinogenesis (New York) (01-08-2013)“…Epidemiological and experimental studies suggest that fiber and phenolic compounds might have a protective effect on the development of colon cancer in humans…”
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Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks
Published in Mutagenesis (01-01-2014)“…The toxic mechanisms of cisplatin have been frequently studied in many species and in vitro cell models. The Netherlands Toxicogenomics Centre focuses on…”
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Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach
Published in Omics (Larchmont, N.Y.) (01-02-2013)“…Drug-induced hepatotoxicity is a leading cause of attrition for candidate pharmaceuticals in development. New preclinical screening methods are crucial to…”
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