Search Results - "Livezey, Jeffrey"
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Meropenem pharmacokinetics in critically ill patients with or without burn treated with or without continuous veno‐venous haemofiltration
Published in British journal of clinical pharmacology (01-05-2022)“…Introduction Severe burn injury involves widespread skin and tissue damage leading to systemic inflammation, hypermetabolism and multi‐organ failure. The…”
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Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study
Published in The Journal of infectious diseases (01-09-2016)“…Background. Three full doses of RTS,S/AS01 malaria vaccine provides partial protection against controlled human malaria parasite infection (CHMI) and natural…”
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3
Pharmacokinetics, safety and efficacy of intra‐articular non‐steroidal anti‐inflammatory drug injections for the treatment of osteoarthritis: A narrative review
Published in Journal of clinical pharmacy and therapeutics (01-08-2022)“…What is known and Objective Osteoarthritis (OA) is a common cause of joint disease and activity limitation in adults. Common therapies to treat OA‐related pain…”
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4
Population Pharmacokinetic Modeling and Simulations of Imipenem in Burn Patients With and Without Continuous Venovenous Hemofiltration in the Military Health System
Published in Journal of clinical pharmacology (01-09-2021)“…Continuous venovenous hemofiltration (CVVH) is a life‐sustaining procedure in patients with severe burns and acute kidney injury. Physiologic changes from burn…”
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Efficacy of drug treatment for severe melioidosis and eradication treatment of melioidosis: A systematic review and network meta-analysis
Published in PLoS neglected tropical diseases (01-06-2023)“…This systematic review and network meta-analysis (NMA) aimed to compare the efficacy of all available treatments for severe melioidosis in decreasing hospital…”
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Semimechanistic Modeling of the Effects of Blast Overpressure Exposure on Cefazolin Pharmacokinetics in Mice
Published in The Journal of pharmacology and experimental therapeutics (01-11-2021)“…Cefazolin is a first-line antibiotic to treat infection related to deployment-associated blast injuries. Prior literature demonstrated a 331% increase…”
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Pharmacokinetics of piperacillin and tazobactam in critically Ill patients treated with continuous kidney replacement therapy: A mini‐review and population pharmacokinetic analysis
Published in Journal of clinical pharmacy and therapeutics (01-08-2022)“…What is known and objective Timely and appropriate dosing of antibiotics is essential for the treatment of bacterial sepsis. Critically ill patients treated…”
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Evaluation of Pharmacogenomics Testing of Cytochrome P450 Enzymes in the Military Health System From 2015 to 2020
Published in Military medicine (30-12-2021)“…ABSTRACT Pharmacogenomics (PGx) plays a fundamental role in personalized medicine, providing an evidence-based treatment approach centered on the relationship…”
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Prevalence of intestinal parasitic infections, genotypes, and drug susceptibility of 'Giardia lamblia' among preschool and school-aged children: A cross-sectional study in Thailand
Published in Tropical medicine and infectious disease (01-08-2023)“…This study aimed to estimate the prevalence of intestinal parasitic infections in children and assess the drug susceptibility and genotypes/assemblages of…”
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Applying Pharmacogenomic Guidelines to Combat Medical Care
Published in Military medicine (01-01-2022)“…ABSTRACT Pharmacogenomics is a pillar of personalized medicine that has the potential to deliver optimized treatment in many medical settings. Military…”
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Prescription Patterns and Relationship to Pharmacogenomics Testing in the Military Health System
Published in Military medicine (01-01-2022)“…ABSTRACT Introduction Clinical utilization of pharmacogenomics (PGx) testing is highly institutionally dependent, and little information is known about…”
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Toward Personalized Medicine Implementation: Survey of Military Medicine Providers in the Area of Pharmacogenomics
Published in Military medicine (02-03-2020)“…Abstract Introduction Personalized medicine is the right treatment, to the right patient, at the right dose. Knowledge of genetic predisposition to variable…”
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Risk of type 2 diabetes mellitus by antimuscarinic agents among adult females receiving care in the military health system
Published in Pharmacoepidemiology and drug safety (01-12-2020)“…Purpose To explore patterns of antimuscarinic medication as a risk factor for type 2 diabetes mellitus (T2DM). Methods This is a retrospective cohort study of…”
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Comparison of Piperacillin and Tazobactam Pharmacokinetics in Critically Ill Patients with Trauma or with Burn
Published in Antibiotics (Basel) (04-05-2022)“…Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of…”
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An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model
Published in Malaria journal (16-09-2020)“…Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis…”
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Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection
Published in npj vaccines (17-11-2024)“…Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial…”
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BRAF mutations are uncommon in papillary thyroid cancer of young patients
Published in Thyroid (New York, N.Y.) (01-04-2005)“…Mortality is low for young patients (younger than 21 years) with papillary thyroid cancer (PTC), and different mutations might contribute to this. Previous…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Human Challenge Trials: Too Risky, Too Soon
Published in The Journal of infectious diseases (06-07-2020)Get full text
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PCGEM1, a Prostate-Specific Gene, Is Overexpressed in Prostate Cancer
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2000)“…A prostate-specific gene, PCGEM1, was identified by differential display analysis of paired normal and prostate cancer tissues. Multiple tissue Northern blot…”
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SARS-CoV-2 Human Challenge Trials: Too Risky, Too Soon
Published in The Journal of infectious diseases (04-06-2020)Get full text
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