Search Results - "Livermore, D. M"

Has the era of untreatable infections arrived? by LIVERMORE, David M

“…Antibiotic resistance is a major public health concern, with fears expressed that we shortly will run out of antibiotics. In reality, the picture is more…”
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Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing by Schmidt, K, Mwaigwisya, S, Crossman, L C, Doumith, M, Munroe, D, Pires, C, Khan, A M, Woodford, N, Saunders, N J, Wain, J, O'Grady, J, Livermore, D M

“…The introduction of metagenomic sequencing to diagnostic microbiology has been hampered by slowness, cost and complexity. We explored whether MinION nanopore…”
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Phylogenetic diversity of Escherichia coli strains producing NDM-type carbapenemases by Mushtaq, S., Irfan, S., Sarma, J. B., Doumith, M., Pike, R., Pitout, J., Livermore, D. M., Woodford, N.

“…Background The global accumulation of Escherichia coli with CTX-M extended-spectrum β-lactamases partly reflects the dissemination of clonal lineages, notably…”
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Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates by LIVERMORE, D. M, MUSHTAQ, S, WARNER, M, ZHANG, J.-C, MAHARJAN, S, DOUMITH, M, WOODFORD, N

“…the emergence of carbapenemases in Enterobacteriaceae is driving a search for therapeutic alternatives. We tested ACHN-490, a sisomicin derivative that evades…”
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Rapid identification of major Escherichia coli sequence types causing urinary tract and bloodstream infections by Doumith, M, Day, M, Ciesielczuk, H, Hope, R, Underwood, A, Reynolds, R, Wain, J, Livermore, D M, Woodford, N

“…Escherichia coli sequence types (STs) 69, 73, 95, and 131 are collectively responsible for a large proportion of E. coli urinary tract and bloodstream…”
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Multiple Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa: Our Worst Nightmare? by Livermore, David M.

“…Pseudomonas aeruginosa carries multiresistance plasmids less often than does Klebsiella pneumoniae, develops mutational resistance to cephalosporins less…”
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Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database by Petersen, I, Johnson, A M, Islam, A, Duckworth, G, Livermore, D M, Hayward, A C

“…Objective To determine the extent to which antibiotics reduce the risk of serious complications after common respiratory tract infections.Design Retrospective…”
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Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe by Cantón, R., Akóva, M., Carmeli, Y., Giske, C.G., Glupczynski, Y., Gniadkowski, M., Livermore, D.M., Miriagou, V., Naas, T., Rossolini, G.M., Samuelsen, Ø., Seifert, H., Woodford, N., Nordmann, P.

“…Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in Europe in the 1990s, are now increasingly being identified at an alarming…”
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Carbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts by Grundmann, H, Livermore, D M, Giske, C G, Canton, R, Rossolini, G M, Campos, J, Vatopoulos, A, Gniadkowski, M, Toth, A, Pfeifer, Y, Jarlier, V, Carmeli, Y

“…The emergence and global spread of carbapenemase-producing Enterobacteriaceae is of great concern to health services worldwide. These bacteria are often…”
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Activity of chequerboard combinations of ceftaroline and NXL104 versus β-lactamase-producing Enterobacteriaceae by Mushtaq, S., Warner, M., Williams, G., Critchley, I., Livermore, D. M.

“…Background Ceftaroline is a novel oxyimino-cephalosporin, strongly active against methicillin-resistant staphylococci and pneumococci. It is active against…”
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beta-Lactamases in laboratory and clinical resistance by LIVERMORE, D. M

“…Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Colonization of residents and staff of a long-term-care facility and adjacent acute-care hospital geriatric unit by multiresistant bacteria by March, A., Aschbacher, R., Dhanji, H., Livermore, D.M., Böttcher, A., Sleghel, F., Maggi, S., Noale, M., Larcher, C., Woodford, N.

“…Long-term-care facilities (LTCFs) are reservoirs of resistant bacteria. We undertook a point-prevalence survey and risk factor analysis for specific resistance…”
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Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum β-lactamases in the UK by Woodford, N., Ward, M. E., Kaufmann, M. E., Turton, J., Fagan, E. J., James, D., Johnson, A. P., Pike, R., Warner, M., Cheasty, T., Pearson, A., Harry, S., Leach, J. B., Loughrey, A., Lowes, J. A., Warren, R. E., Livermore, D. M.

“…Objectives: During 2003, the Health Protection Agency's Antibiotic Resistance Monitoring and Reference Laboratory began to receive isolates of Escherichia coli…”
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Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013 by Glasner, C, Albiger, B, Buist, G, Tambić Andrasević, A, Canton, R, Carmeli, Y, Friedrich, A W, Giske, C G, Glupczynski, Y, Gniadkowski, M, Livermore, D M, Nordmann, P, Poirel, L, Rossolini, G M, Seifert, H, Vatopoulos, A, Walsh, T, Woodford, N, Donker, T, Monnet, D L, Grundmann, H

“…The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a threat to healthcare delivery, although its extent differs substantially from country to…”
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Linezolid in vitro: mechanism and antibacterial spectrum by Livermore, David M

“…Oxazolidinones are prominent among the new Gram-positive antimicrobial agents now becoming available. They were discovered by DuPont Pharmaceuticals in the…”
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Imported chicken meat as a potential source of quinolone-resistant Escherichia coli producing extended-spectrum β-lactamases in the UK by Warren, R. E., Ensor, V. M., O'Neill, P., Butler, V., Taylor, J., Nye, K., Harvey, M., Livermore, D. M., Woodford, N., Hawkey, P. M.

“…Objectives Escherichia coli producing CTX-M-15 enzyme began to rapidly spread in the UK from around 2003 but other types also occur, notably CTX-M-14. We…”
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Outbreak of Carbapenem-Resistant Pseudomonas aeruginosa Producing VIM-8, a Novel Metallo-β-Lactamase, in a Tertiary Care Center in Cali, Colombia by CRESPO, M. P, WOODFORD, N, SINCLAIR, A, KAUFMANN, M. E, TURTON, J, GLOVER, J, VELEZ, J. D, CASTANEDA, C. R, RECALDE, M, LIVERMORE, D. M

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CTX-M: changing the face of ESBLs in the UK by Livermore, D. M., Hawkey, P. M.

“…The UK has experienced a sudden rise in extended-spectrum β-lactamase (ESBL) rates, largely due to the appearance and spread of Escherichia coli producing…”
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Molecular characterization of plasmids encoding CTX-M-15 β-lactamases from Escherichia coli strains in the United Kingdom by Karisik, E., Ellington, M. J., Pike, R., Warren, R. E., Livermore, D. M., Woodford, N.

“…Objectives: The UK, like other countries worldwide, has a growing problem with CTX-M β-lactamase-producing Escherichia coli. Five major clonally related…”
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In vitro activity of retapamulin against Staphylococcus aureus isolates resistant to fusidic acid and mupirocin by Woodford, N., Afzal-Shah, M., Warner, M., Livermore, D. M.

“…Objectives We determined the in vitro activity of retapamulin, a novel pleuromutilin antibiotic, against 664 Staphylococcus aureus isolates from the UK,…”
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