Search Results - "Lively, Julie C."

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins by Reynolds, Louise E, Wyder, Lorenza, Lively, Julie C, Taverna, Daniela, Robinson, Stephen D, Huang, Xiaozhu, Sheppard, Dean, Hynes, Richard O, Hodivala-Dilke, Kairbaan M

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Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis by Maeshima, Yohei, Sudhakar, Akulapalli, Lively, Julie C., Ueki, Kohjiro, Kharbanda, Surender, Kahn, C. Ronald, Sonenberg, Nahum, Hynes, Richard O., Kalluri, Raghu

“…Tumstatin is a 28-kilodalton fragment of type IV collagen that displays both anti-angiogenic and proapoptotic activity. Here we show that tumstatin functions…”
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Physiological levels of tumstatin, a fragment of collagen IV α3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via αVβ3 integrin by Hamano, Yuki, Zeisberg, Michael, Sugimoto, Hikaru, Lively, Julie C, Maeshima, Yohei, Yang, Changqing, Hynes, Richard O, Werb, Zena, Sudhakar, Akulapalli, Kalluri, Raghu

“…We demonstrate a physiological role for tumstatin, a cleavage fragment of the α3 chain of type IV collagen (Col IVα3), which is present in the circulation…”
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Integrin α1β1 and α2β1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment by CHANGQING YANG, ZEISBERG, Michael, LIVELY, Julie C, NYBERG, Pia, AFDHAL, Nezam, KALLURI, Raghu

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Elevated Flk1 (Vascular Endothelial Growth Factor Receptor 2) Signaling Mediates Enhanced Angiogenesis in β3-Integrin–Deficient Mice by Reynolds, Andrew R., Reynolds, Louise E., Nagel, Tobi E., Lively, Julie C., Robinson, Stephen D., Hicklin, Daniel J., Bodary, Sarah C., Hodivala-Dilke, Kairbaan M.

“…Tumor growth, tumor angiogenesis, and vascular endothelial growth factor (VEGF)–specific angiogenesis are all enhanced in β3-integrin–null mice. Furthermore,…”
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Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment by Yang, Changqing, Zeisberg, Michael, Lively, Julie C, Nyberg, Pia, Afdhal, Nezam, Kalluri, Raghu

“…As with many types of cancer, cell motility is an important factor in the progression and metastasis of hepatocellular carcinomas (HCC). HCC is associated with…”
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Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice by Reynolds, Andrew R, Reynolds, Louise E, Nagel, Tobi E, Lively, Julie C, Robinson, Stephen D, Hicklin, Daniel J, Bodary, Sarah C, Hodivala-Dilke, Kairbaan M

“…Tumor growth, tumor angiogenesis, and vascular endothelial growth factor (VEGF)-specific angiogenesis are all enhanced in beta(3)-integrin-null mice…”
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Elevated Flk1 (Vascular Endothelial Growth Factor Receptor 2) Signaling Mediates Enhanced Angiogenesis in beta sub(3)-Integrin-Deficient Mice by Reynolds, Andrew R, Reynolds, Louise E, Nagel, Tobi E, Lively, Julie C, Robinson, Stephen D, Hicklin, Daniel J, Bodary, Sarah C, Hodivala-Dilke, Kairbaan M

“…Tumor growth, tumor angiogenesis, and vascular endothelial growth factor (VEGF)-specific angiogenesis are all enhanced in beta sub(3)-integrin-null mice…”
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Elevated Flkl (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in β3-Integrin-Deficient mice by REYNOLDS, Andrew R, REYNOLDS, Louise E, NAGEL, Tobi E, LIVELY, Julie C, ROBINSON, Stephen D, HICKLIN, Daniel J, BODARY, Sarah C, HODIVALA-DILKE, Kairbaan M

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Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin by Hamano, Yuki, Zeisberg, Michael, Sugimoto, Hikaru, Lively, Julie C, Maeshima, Yohei, Yang, Changqing, Hynes, Richard O, Werb, Zena, Sudhakar, Akulapalli, Kalluri, Raghu

“…We demonstrate a physiological role for tumstatin, a cleavage fragment of the alpha3 chain of type IV collagen (Col IValpha3), which is present in the…”
Get full text

Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins by Reynolds, Louise E, Wyder, Lorenza, Lively, Julie C, Taverna, Daniela, Robinson, Stephen D, Huang, Xiaozhu, Sheppard, Dean, Hynes, Richard O, Hodivala-Dilke, Kairbaan M

“…Inhibition of alphavbeta3 or alphavbeta5 integrin function has been reported to suppress neovascularization and tumor growth, suggesting that these integrins…”
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Enhanced pathological angiogenesis in mice lacking β 3 integrin or β 3 and β 5 integrins by Hodivala-Dilke, Kairbaan M, Reynolds, Louise E, Wyder, Lorenza, Lively, Julie C, Taverna, Daniela, Robinson, Stephen D, Huang, Xiaozhu, Sheppard, Dean, Hynes, Richard O

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Enhanced pathological angiogenesis in mice lacking [beta]3 integrin or [beta]3 and [beta]5 integrins by Reynolds, Louise E, Wyder, Lorenza, Lively, Julie C, Taverna, Daniela, Robinson, Stephen D, Huang, Xiaozhu, Sheppard, Dean, Hynes, Richard O, Hodivala-Dilke, Kairbaan M

“…Inhibition of alphavbeta3 or alphavbeta5 integrin function has been reported to suppress neovascularization and tumor growth, suggesting that these integrins…”
Get full text