Search Results - "Liu, Zongcai"
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Enhanced histone H3 acetylation of the PD-L1 promoter via the COP1/c-Jun/HDAC3 axis is required for PD-L1 expression in drug-resistant cancer cells
Published in Journal of experimental & clinical cancer research (05-02-2020)“…Drug resistance is a major obstacle to treating cancers because it desensitizes cancer cells to chemotherapy. Recently, attention has been focused on changes…”
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Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation
Published in Environment international (01-10-2024)“…[Display omitted] •Continuous cold exposure decreases plasma lysine level both in humans and mice.•Plasma lysine level is strongly correlated with cold…”
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Genome-Wide Identification and Characterization of microRNAs in Developing Grains of Zea mays L
Published in PloS one (15-04-2016)“…The development and maturation of maize kernel involves meticulous and fine gene regulation at transcriptional and post-transcriptional levels, and miRNAs play…”
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Natural history and outcome of nonketotic hyperglycinemia in China
Published in Frontiers in neurology (14-08-2024)“…Nonketotic hyperglycinemia (NKH) is a rare, life-threatening genetic disorder. The patients usually show heterogeneous and nonspecific symptoms, resulting in…”
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Assessment of the diagnostic value of serum ceruloplasmin for Wilson's disease in children
Published in BMC gastroenterology (16-03-2022)“…Serum ceruloplasmin is one of the major diagnostic parameters for Wilson's disease (WD). Age and gender difference of serum ceruloplasmin remain controversy…”
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Distinct severity of phenotype in Hajdu-Cheney syndrome: a case report and literature review
Published in BMC musculoskeletal disorders (06-03-2020)“…Hajdu-Cheney syndrome (HCS) is a rare inherited skeletal disorder caused by pathogenic mutations in exon 34 of NOTCH2. Its highly variable phenotypes make…”
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Amana hejiaqingii (Liliaceae), a New Species from the Dabie Mountains, China
Published in Taxonomy (Basel, Switzerland) (01-09-2022)“…In this paper, a new species from Central China, Amana hejiaqingii (Liliaceae), is described and illustrated. It resembles A. anhuiensis and A. tianmuensis but…”
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Chloroplast genome and phylogenetic analysis of Grewia biloba
Published in Mitochondrial DNA. Part B. Resources (03-06-2021)“…Grewia biloba is a potential medicinal and ornamental resource, and this study is the first to assemble the chloroplast genome of this species using…”
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EGF is highly expressed in hepatocellular carcinoma (HCC) and promotes motility of HCC cells via fibronectin
Published in Journal of cellular biochemistry (01-05-2018)“…Better understanding of metastasis process would allow for the development of effective approaches to treat hepatocellular carcinoma (HCC). Recent literature…”
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SCD1 sustains brown fat sympathetic innervation and thermogenesis during the long-term cold exposure
Published in Biochemical and biophysical research communications (12-02-2024)“…Brown fat adipose tissue (BAT) is a therapeutic potential target to improve obesity, diabetes and cold acclimation in mammals. During the long-term cold…”
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Circ-FOXO3 inhibits triple-negative breast cancer growth and metastasis via regulating WHSC1-H3K36me2-Zeb2 axis
Published in Cellular signalling (01-05-2024)“…Circular RNAs (circRNAs), a subclass of non-coding RNAs characterized by covalently closed continuous loops, play a key role in tumorigenesis and…”
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Poliovirus receptor (PVR) mediates carboplatin-induced PD-L1 expression in non-small-cell lung cancer cells
Published in Biochimica et biophysica acta. General subjects (01-10-2023)“…Programmed death-ligand-1 (PD-L1) is an immune suppressor that inhibits T cell based immunity. Anti-PD-L1/PD-1 immunotherapy benefits those patients receiving…”
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Interleukin-1 beta signals through the ERK signalling pathway to modulate human placental trophoblast migration and invasion in the first trimester of pregnancy
Published in Placenta (Eastbourne) (01-06-2024)“…Interleukin-1 beta (IL-1β) can promote cell migration, invasion and metastasis in various cancer cells. The mechanism of its role in human trophoblast has not…”
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Genetic analysis of 63 Chinese patients with mucopolysaccharidosis type II: Functional characterization of seven novel IDS variants
Published in Clinica chimica acta (01-04-2019)“…Mucopolysaccharidosis type II (MPS II) is an X-linked recessive lysosomal storage disorder resulting from the deficiency of the enzyme iduronate-2-sulfatase…”
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The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells
Published in Cancer communications (London, England) (01-01-2021)“…Background Immunotherapy has been shown to be a promising strategy against human cancers. A better understanding of the immune regulation in hepatocellular…”
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A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin-related metabolic disturbance and infancy-onset motor impairments
Published in Metabolism, clinical and experimental (01-05-2019)“…GTP cyclohydrolase I (GTPCH) deficiency could impair the synthesis of tetrahydrobiopterin and causes metabolic diseases involving phenylalanine catabolism,…”
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Clinical and molecular characteristics of patients with Gaucher disease in Southern China
Published in Blood cells, molecules, & diseases (01-02-2018)“…Gaucher disease (GD) is a common lysosomal storage disorder caused by the deficiency of acid β-glucosidase, due to mutations in the GBA gene. To explore the…”
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Clinical features and mutational analysis in 114 young children with Wilson disease from South China
Published in American journal of medical genetics. Part A (01-08-2019)“…Wilson disease (WD) is a rare autosomal recessive disorder caused by mutations in the ATP7B gene. Clinical features and mutational analysis of Chinese children…”
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Features of liver injury in 138 Chinese patients with NICCD
Published in Journal of pediatric endocrinology & metabolism : JPEM (15-12-2023)“…To find biochemical and molecular markers can assist in identifying serious liver damage of neonatal intrahepatic cholestasis caused by citrin deficiency…”
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Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure
Published in Cytotherapy (Oxford, England) (01-09-2014)“…Abstract Background aims Acute liver failure (ALF), a life-threatening disease characterized by the sudden loss of hepatic function, can occur after an…”
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