Search Results - "Liu, Zaoqu"

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer by Liu, Zaoqu, Liu, Long, Weng, Siyuan, Guo, Chunguang, Dang, Qin, Xu, Hui, Wang, Libo, Lu, Taoyuan, Zhang, Yuyuan, Sun, Zhenqiang, Han, Xinwei

“…Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in colorectal cancer (CRC). Nevertheless, the clinical significance of…”
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Immunosenescence: molecular mechanisms and diseases by Liu, Zaoqu, Liang, Qimeng, Ren, Yuqing, Guo, Chunguang, Ge, Xiaoyong, Wang, Libo, Cheng, Quan, Luo, Peng, Zhang, Yi, Han, Xinwei

“…Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms are linked to innate and adaptive immune dysfunction that…”
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Stemness Refines the Classification of Colorectal Cancer With Stratified Prognosis, Multi-Omics Landscape, Potential Mechanisms, and Treatment Options by Liu, Zaoqu, Xu, Hui, Weng, Siyuan, Ren, Yuqing, Han, Xinwei

“…Stemness refers to the capacities of self-renewal and repopulation, which contributes to the progression, relapse, and drug resistance of colorectal cancer…”
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Ferroptosis: a double-edged sword mediating immune tolerance of cancer by Dang, Qin, Sun, Ziqi, Wang, Yang, Wang, Libo, Liu, Zaoqu, Han, Xinwei

“…The term ferroptosis was put forward in 2012 and has been researched exponentially over the past few years. Ferroptosis is an unconventional pattern of…”
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Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts by Wang, Yuchen, Zhang, Hao, Liu, Chao, Wang, Zeyu, Wu, Wantao, Zhang, Nan, Zhang, Longbo, Hu, Jason, Luo, Peng, Zhang, Jian, Liu, Zaoqu, Peng, Yun, Liu, Zhixiong, Tang, Lanhua, Cheng, Quan

“…Abstract The discovery of immune checkpoint inhibitors (ICIs) has now been universally acknowledged as a significant breakthrough in tumor therapy after the…”
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Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatment by Gao, Zhifei, Bai, Yifeng, Lin, Anqi, Jiang, Aimin, Zhou, Chaozheng, Cheng, Quan, Liu, Zaoqu, Chen, Xin, Zhang, Jian, Luo, Peng

“…As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of immunotherapy in recent years. They have extraordinary antitumor…”
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Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials by Zhang, Hao, Yue, Xinghai, Chen, Zhe, Liu, Chao, Wu, Wantao, Zhang, Nan, Liu, Zaoqu, Yang, Liping, Jiang, Qing, Cheng, Quan, Luo, Peng, Liu, Guodong

“…Abstract Despite centuries since the discovery and study of cancer, cancer is still a lethal and intractable health issue worldwide. Cancer-associated…”
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A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma by Liu, Zaoqu, Zhang, Yuyuan, Shi, Chengcheng, Zhou, Xueliang, Xu, Kaihao, Jiao, Dechao, Sun, Zhenqiang, Han, Xinwei

“…The tumor immunological microenvironment (TIME) has a prominent impact on prognosis and immunotherapy. However, the heterogeneous TIME and the mechanisms by…”
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Comprehensive machine-learning survival framework develops a consensus model in large-scale multicenter cohorts for pancreatic cancer by Wang, Libo, Liu, Zaoqu, Liang, Ruopeng, Wang, Weijie, Zhu, Rongtao, Li, Jian, Xing, Zhe, Weng, Siyuan, Han, Xinwei, Sun, Yu-Ling

“…As the most aggressive tumor, the outcome of pancreatic cancer (PACA) has not improved observably over the last decade. Anatomy-based TNM staging does not…”
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Biological and pharmacological roles of m6A modifications in cancer drug resistance by Liu, Zaoqu, Zou, Haijiao, Dang, Qin, Xu, Hui, Liu, Long, Zhang, Yuyuan, Lv, Jinxiang, Li, Huanyun, Zhou, Zhaokai, Han, Xinwei

“…Abstract Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant cancers exhibit complex molecular mechanisms to hit back…”
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A New Trend in Cancer Treatment: The Combination of Epigenetics and Immunotherapy by Liu, Zaoqu, Ren, Yuqing, Weng, Siyuan, Xu, Hui, Li, Lifeng, Han, Xinwei

“…In recent years, immunotherapy has become a hot spot in the treatment of tumors. As an emerging treatment, it solves many problems in traditional cancer…”
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Construction of antibacterial photothermal PCL/AgNPs/BP nanofibers for infected wound healing by Zhao, Yanan, Liu, Yiming, Tian, Chuan, Liu, Zaoqu, Wu, Kunpeng, Zhang, Chengzhi, Han, Xinwei

“…[Display omitted] •BP is used to solve the shortcoming of AgNPs easy polymerization.•This nanofibers exert excellent antibacterial activity and good…”
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The Identification and Validation of Two Heterogenous Subtypes and a Risk Signature Based on Ferroptosis in Hepatocellular Carcinoma by Liu, Zaoqu, Wang, Libo, Liu, Long, Lu, Taoyuan, Jiao, Dechao, Sun, Yuling, Han, Xinwei

“…Ferroptosis is essential for tumorigenesis and progression of hepatocellular carcinoma (HCC). The heterogeneity of ferroptosis and its relationship with tumor…”
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Editorial: Multidimensionally decoding the impact of tumor heterogeneity on immunotherapy responsiveness in gastrointestinal tumors by Wang, Ruizhi, Wang, Libo, Ren, Yuqing, Han, Xinwei, Liu, Zaoqu

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Recent advances and applications of CRISPR-Cas9 in cancer immunotherapy by Liu, Zaoqu, Shi, Meixin, Ren, Yuqing, Xu, Hui, Weng, Siyuan, Ning, Wenjing, Ge, Xiaoyong, Liu, Long, Guo, Chunguang, Duo, Mengjie, Li, Lifeng, Li, Jing, Han, Xinwei

“…The incidence and mortality of cancer are the major health issue worldwide. Apart from the treatments developed to date, the unsatisfactory therapeutic effects…”
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The role of DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy by Shi, Congqi, Qin, Kaiyu, Lin, Anqi, Jiang, Aimin, Cheng, Quan, Liu, Zaoqu, Zhang, Jian, Luo, Peng

“…Abstract As our understanding of the mechanisms of cancer treatment has increased, a growing number of studies demonstrate pathways through which DNA damage…”
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Gene interaction perturbation network deciphers a high-resolution taxonomy in colorectal cancer by Liu, Zaoqu, Weng, Siyuan, Dang, Qin, Xu, Hui, Ren, Yuqing, Guo, Chunguang, Xing, Zhe, Sun, Zhenqiang, Han, Xinwei

“…Molecular subtypes of colorectal cancer (CRC) are currently identified via the snapshot transcriptional profiles, largely ignoring the dynamic changes of gene…”
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Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer by Liu, Zaoqu, Guo, ChunGuang, Dang, Qin, Wang, Libo, Liu, Long, Weng, Siyuan, Xu, Hui, Lu, Taoyuan, Sun, Zhenqiang, Han, Xinwei

“…Long non-coding RNAs (lncRNAs) have recently emerged as essential biomarkers of cancer progression. However, studies are limited regarding lncRNAs correlated…”
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Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment by Xu, Hui, Cao, Chenxi, Ren, Yuqing, Weng, Siyuan, Liu, Long, Guo, Chunguang, Wang, Libo, Han, Xinwei, Ren, Jianzhuang, Liu, Zaoqu

“…Fecal microbiome transplantation (FMT) from healthy donors is one of the techniques for restoration of the dysbiotic gut, which is increasingly being used to…”
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Tumor buster - where will the CAR-T cell therapy 'missile' go? by Qu, Chunrun, Zhang, Hao, Cao, Hui, Tang, Lanhua, Mo, Haoyang, Liu, Fangkun, Zhang, Liyang, Yi, Zhenjie, Long, Lifu, Yan, Luzhe, Wang, Zeyu, Zhang, Nan, Luo, Peng, Zhang, Jian, Liu, Zaoqu, Ye, Weijie, Liu, Zhixiong, Cheng, Quan

“…Chimeric antigen receptor (CAR) T cell (CAR-T cell) therapy based on gene editing technology represents a significant breakthrough in personalized…”
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