Search Results - "Liu, ZaiXin"
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Thermal Tribo-Dynamic Behaviors of Water-Lubricated Bearings during Start-Up with Journal Shape Error
Published in Lubricants (01-04-2024)“…In practical scenarios, journal bearings often exhibit shape errors due to machining imperfections and operational wear. These deviations from perfect…”
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2
Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization
Published in PLoS pathogens (01-04-2021)“…The development of a universal vaccine against foot-and-mouth disease virus (FMDV) is hindered by cross-serotype antigenic diversity and by a lack of knowledge…”
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3
High-throughput screening unveils nitazoxanide as a potent PRRSV inhibitor by targeting NMRAL1
Published in Nature communications (06-06-2024)“…Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to the global swine industry, yet effective prevention and control measures…”
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4
Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies
Published in PLoS pathogens (20-11-2023)“…Foot-and-mouth disease virus (FMDV) serotype A is antigenically most variable within serotypes. The structures of conserved and variable antigenic sites were…”
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5
Porcine reproductive and respiratory syndrome virus nonstructural protein 2 promotes the autophagic degradation of adaptor protein SH3KBP1 to antagonize host innate immune responses by enhancing K63-linked polyubiquitination of RIG-I
Published in PLoS pathogens (28-10-2024)“…Non-structural protein 2 (NSP2) of PRRSV is highly variable and plays crucial roles in the virus's life cycle. To elucidate the function of NSP2 during PRRSV…”
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6
Engineering viable foot-and-mouth disease viruses with increased acid stability facilitate the development of improved vaccines
Published in Applied microbiology and biotechnology (01-02-2020)“…Foot-and-mouth disease virus (FMDV), the most acid-unstable virus among picornaviruses , tends to disassemble into pentamers at pH values slightly below…”
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7
The long non-coding RNA LNC_000397 negatively regulates PRRSV replication through induction of interferon-stimulated genes
Published in Virology journal (05-03-2022)“…Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant threats to the global swine industry. It is of great importance to…”
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Rational design and efficacy of a multi-epitope recombinant protein vaccine against foot-and-mouth disease virus serotype A in pigs
Published in Antiviral research (01-04-2017)“…Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, and outbreaks of this disease are often economically catastrophic…”
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Modification of the second translation initiation site restricts the replication of foot-and-mouth disease virus in PK-15 cells
Published in Applied microbiology and biotechnology (01-10-2020)“…The translation initiation of foot-and-mouth disease virus (FMDV) occurs at two alternative initiation sites (Lab AUG and Lb AUG). Usually, the Lb AUG is more…”
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10
Purification of foot-and-mouth disease virus by heparin as ligand for certain strains
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-04-2017)“…•FMD strains displayed different affinities to heparin resins, heparin affinity chromatography would reach perfect results only when heparin was ligand of…”
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11
The rescue and selection of thermally stable type O vaccine candidate strains of foot-and-mouth disease virus
Published in Archives of virology (01-08-2021)“…Inactivated foot-and-mouth disease virus (FMDV) vaccines have been used widely to control foot-and-mouth disease (FMD). However, the virions (146S) of this…”
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12
Evaluation of immunogenicity and cross-reactive responses of vaccines prepared from two chimeric serotype O foot-and-mouth disease viruses in pigs and cattle
Published in Veterinary research (Paris) (08-07-2022)“…Abstract Foot-and-mouth disease (FMD) remains a very serious barrier to agricultural development and the international trade of animals and animal products…”
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13
Genome-wide analysis of long noncoding RNA profiling in PRRSV-infected PAM cells by RNA sequencing
Published in Scientific reports (10-07-2017)“…Porcine reproductive and respiratory syndrome (PRRS) is a major threat to the global swine industry and causes tremendous economic losses. Its causative agent,…”
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14
Development of a Blocking ELISA Using a Monoclonal Antibody to a Dominant Epitope in Non-Structural Protein 3A of Foot-and-Mouth Disease Virus, as a Matching Test for a Negative-Marker Vaccine
Published in PloS one (20-01-2017)“…Foot-and-mouth disease (FMD) is a devastating animal disease. Strategies for differentiation of infected from vaccinated animals (DIVA) remain very important…”
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Development of Foot-and-Mouth Disease Virus-Neutralizing Monoclonal Antibodies Derived From Plasmablasts of Infected Cattle and Their Germline Gene Usage
Published in Frontiers in immunology (06-12-2019)“…Cattle are susceptible to foot-and-mouth disease virus (FMDV), and neutralizing antibodies are critical for protection against FMDV infection in this species…”
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16
The pH stability of foot-and-mouth disease virus
Published in Virology journal (28-11-2017)“…ᅟ: This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid…”
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17
Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A
Published in Microbiology spectrum (15-06-2023)“…Senecavirus A (SVA) is an emerging viral pathogen related to vesicular disease and neonatal mortality in swine, which results in enormous economic losses to…”
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18
Identification of the largest non-essential regions of the C-terminal portion in 3A protein of foot-and-mouth disease virus for replication in cell culture
Published in Virology journal (14-09-2020)“…Recent study has shown that the C-terminal portion of 3A (amino acids (aa) 81-153) is not essential for foot-and-mouth disease virus replication in cell…”
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The molecular characteristic analysis of PRRSV GSWW/2015 strain and its pathogenicity to pigs
Published in BMC veterinary research (17-08-2018)“…Porcine reproductive and respiratory syndrome (PRRS) is a severe disease, causing great economic losses to the pig industry. The causative agent, porcine…”
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20
Whole-genome analysis of the recombination and evolution of newly identified NADC30-like porcine reproductive and respiratory syndrome virus strains circulated in Gansu province of China in 2023
Published in Frontiers in veterinary science (2024)“…Porcine reproductive and respiratory syndrome virus (PRRSV) remains one of the major threats to swine industry, resulting in huge economic losses worldwide…”
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