Search Results - "Liu, Yingle"
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Detection of Covid-19 in Children in Early January 2020 in Wuhan, China
Published in The New England journal of medicine (02-04-2020)“…A retrospective analysis of routine surveillance data involving children hospitalized in central Wuhan, China, for acute lower respiratory infection in early…”
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Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020
Published in Clinica chimica acta (01-06-2020)“…•The SARS-CoV-2 NAT positive rate was about 38% for the total 4880 specimens.•Male and older population had a significant higher positive rates.•57% was…”
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Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals
Published in Nature (London) (25-06-2020)“…The ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly on a global scale. Although it is clear that severe acute respiratory syndrome…”
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Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
Published in Emerging microbes & infections (01-01-2020)“…Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak has caused devastating mortality and posed a great threat to public…”
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RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak
Published in Emerging microbes & infections (01-01-2020)“…From December 2019, an outbreak of unusual pneumonia was reported in Wuhan with many cases linked to Huanan Seafood Market that sells seafood as well as live…”
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Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion
Published in Nature communications (09-01-2018)“…Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays…”
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Manganese-Catalyzed Aerobic Oxytrifluoromethylation of Styrene Derivatives Using CF3SO2Na as the Trifluoromethyl Source
Published in Journal of organic chemistry (02-07-2015)“…A mild and practical protocol for manganese-catalyzed aerobic oxytrifluoromethylation of olefinic bonds of styrene derivatives using CF3SO2Na (Langlois’…”
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HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1
Published in PLoS pathogens (01-04-2013)“…Upon recognition of viral components by pattern recognition receptors, such as the toll-like receptors (TLRs) and retinoic acid-inducible gene I (RIG-I)-like…”
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ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens
Published in Emerging microbes & infections (01-01-2020)“…Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and…”
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Complete bio-degradation of poly(butylene adipate-co-terephthalate) via engineered cutinases
Published in Nature communications (24-03-2023)“…Poly(butylene adipate-co-terephthalate) (PBAT), a polyester made of terephthalic acid (TPA), 1,4-butanediol, and adipic acid, is extensively utilized in…”
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EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production
Published in PLoS pathogens (15-11-2019)“…As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease (HFMD) and may develop severe neurological disorders in…”
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EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex
Published in PLoS pathogens (01-01-2017)“…Activation of NLRP3 inflammasome is important for effective host defense against invading pathogen. Together with apoptosis-associated speck-like protein…”
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Co-circulation and genomic recombination of coxsackievirus A16 and enterovirus 71 during a large outbreak of hand, foot, and mouth disease in Central China
Published in PloS one (01-04-2014)“…A total of 1844 patients with hand, foot, and mouth disease (HFMD), most of them were children of age 1-3-year-old, in Central China were hospitalized from…”
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Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2
Published in Protein & cell (01-10-2020)“…Emerging and re-emerging RNA viruses occasionally cause epidemics and pandemics worldwide, such as the on-going outbreak of the novel coronavirus SARS-CoV-2…”
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MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway
Published in Cell reports (Cambridge) (20-10-2020)“…The immune system is not only required for preventing threats exerted by pathogens but also essential for developing immune tolerance to avoid tissue damage…”
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Apelin (APLN) is a biomarker contributing to the diagnosis and prognosis of hepatocellular carcinoma
Published in Scientific reports (03-09-2024)“…Liver cancer, classified as a malignant hepatic tumor, can be divided into two categories: primary, originating within the liver, and secondary, resulting from…”
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Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome
Published in BMC biology (26-11-2020)“…Extracellular adenosine triphosphate (ATP), a key danger-associated molecular pattern (DAMP) molecule, is released to the extracellular medium during…”
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Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation
Published in Virulence (01-12-2020)“…Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD), and even fatal neurological complications. However, the mechanisms underlying EV71…”
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Correction to: The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration
Published in Laboratory investigation (01-11-2021)Get full text
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A liver‐specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication
Published in The FASEB journal (01-12-2011)“…ABSTRACT Regulated gene expression and progeny production are essential for persistent and chronic infection by human pathogens, such as hepatitis B virus…”
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