Search Results - "Liu, Yasmine J."
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A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
Published in Cell metabolism (03-03-2020)“…Slowing down translation in either the cytosol or the mitochondria is a conserved longevity mechanism. Here, we found a non-interventional natural correlation…”
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Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
Published in PLoS genetics (07-03-2019)“…The deregulation of metabolism is a hallmark of aging. As such, changes in the expression of metabolic genes and the profiles of amino acid levels are features…”
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A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans
Published in Scientific reports (25-05-2017)“…Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C…”
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Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans
Published in Scientific reports (01-03-2022)“…Deregulated energy homeostasis represents a hallmark of aging and results from complex gene-by-environment interactions. Here, we discovered that reducing the…”
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Considerations Regarding Public Use of Longevity Interventions
Published in Frontiers in aging (25-04-2022)“…Public attention and interest for longevity interventions are growing. These can include dietary interventions such as intermittent fasting, physical…”
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Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease
Published in Mechanisms of ageing and development (01-03-2020)“…•Mitochondrial fission and fusion are implicated in age-related human pathologies.•Crucial to mitochondrial regulation is their dynamic nature in a network…”
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Mitochondria: A “pacemaker” for species-specific development
Published in Molecular cell (16-03-2023)“…We highlight papers by Diaz-Cuadros et al.1 and Iwata et al.2 that demonstrate the role of mitochondrial metabolism in setting developmental pace through their…”
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Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30
Published in The Journal of cell biology (01-06-2020)“…Mitochondrial form and function are closely interlinked in homeostasis and aging. Inhibiting mitochondrial translation is known to increase lifespan in C…”
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V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
Published in The Journal of cell biology (02-01-2023)“…To adapt mitochondrial function to the ever-changing intra- and extracellular environment, multiple mitochondrial stress response (MSR) pathways, including the…”
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ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH
Published in Journal of hepatology (22-08-2024)“…Recent findings reveal the importance of tryptophan-initiated de novo nicotinamide adenine dinucleotide (NAD+) synthesis in the liver, a process previously…”
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Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity
Published in Ageing research reviews (01-06-2022)“…Life expectancy has increased substantially over the last 150 years. Yet this means that now most people also spend a greater length of time suffering from…”
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