Search Results - "Liu, Xuwan"
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Attenuation of doxorubicin-induced contractile and mitochondrial dysfunction in mouse heart by cellular glutathione peroxidase
Published in Free radical biology & medicine (01-07-2006)“…The cardiac toxicity of doxorubicin (DOX), a potent anticancer anthracycline antibiotic, is believed to be mediated through the generation of reactive oxygen…”
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2
Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity
Published in Biochimica et biophysica acta (01-10-2008)“…Doxorubicin (DOX)-induced cardiotoxicity is thought to be mediated by the generation of superoxide anion radicals (superoxide) from redox cycling of DOX in…”
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3
Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells
Published in Pulmonary pharmacology & therapeutics (01-01-2007)“…Abstract Nicotinic acetylcholine receptors (nAChR) are expressed on non-neuronal cell types, including normal bronchial epithelial cells, and nicotine has been…”
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4
Estrogen Receptor β Functions through Nongenomic Mechanisms in Lung Cancer Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2009)“…Recent studies have shown that estrogens promote the growth of lung cancer cells and may potentially be responsible for increased susceptibility to lung cancer…”
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5
Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells
Published in American journal of physiology. Heart and circulatory physiology (01-06-2006)“…Doxorubicin (Dox) is a chemotherapeutic agent that causes significant cardiotoxicity. We showed previously that Dox activates p53 and induces apoptosis in…”
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6
Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice
Published in American journal of physiology. Heart and circulatory physiology (01-03-2004)“…The present experiments were designed to evaluate the effects of pifithrin-alpha (PFT-alpha), which is a p53 inhibitor, on doxorubicin (DOX)-induced apoptosis…”
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7
Melatonin as an effective protector against doxorubicin-induced cardiotoxicity
Published in American journal of physiology. Heart and circulatory physiology (01-07-2002)“…The present study was designed to explore the protective effects of melatonin and its analogs, 6-hydroxymelatonin and 8-methoxy-2-propionamidotetralin, on the…”
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Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib
Published in Experimental cell research (15-04-2007)“…Gastrin-releasing peptide (GRP) is a mitogen for lung epithelial cells and initiates signaling through a G-protein-coupled receptor, gastrin-releasing peptide…”
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Elevated gastrin-releasing peptide receptor mRNA expression in buccal mucosa: Association with head and neck squamous cell carcinoma
Published in Head & neck (01-02-2013)“…Background Expression of gastrin‐releasing peptide receptor (GRPR) is elevated in mucosa adjacent to head and neck squamous cell carcinoma (HNSCC) compared…”
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10
Protection of pifithrin-α and melatonin against doxorubicin-induced cardiotoxicity
Published 01-01-2003“…The current studies were designed to explore the protective effects of pifithrin-α and melatonin against doxorubicin-induced cardiotoxicity. Doxorubicin was…”
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Dissertation