Search Results - "Liu, Xiongxiong"
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The Research Progress of Mitochondrial Transplantation in the Treatment of Mitochondrial Defective Diseases
Published in International journal of molecular sciences (01-01-2024)“…Mitochondria are double-membrane organelles that are involved in energy production, apoptosis, and signaling in eukaryotic cells. Several studies conducted…”
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Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity
Published in Theranostics (01-01-2019)“…Emerging evidence indicates that reprogramming of energy metabolism involving disturbances in energy production from a defect in cellular respiration with a…”
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Synergism Antiproliferative Effects of Apigenin and Naringenin in NSCLC Cells
Published in Molecules (Basel, Switzerland) (23-06-2023)“…Non-small cell lung cancer (NSCLC) is one of the leading cancer killers. Apigenin (Api) and Naringenin (Nar) are natural bioactive substances obtained in…”
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Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways
Published in Radiotherapy and oncology (01-10-2018)“…Previously, we found genistein could sensitize cancer cells to low linear energy transfer (LET) X-rays via inhibiting DNA-PKcs activities. Especially, high-LET…”
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Sp1 Upregulation Bolsters the Radioresistance of Glioblastoma Cells by Promoting Double Strand Breaks Repair
Published in International journal of molecular sciences (26-06-2023)“…Radioresistance remains a critical obstacle in the clinical management of glioblastoma (GBM) by radiotherapy. Therefore, it is necessary to explore the…”
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MitoQ regulates autophagy by inducing a pseudo-mitochondrial membrane potential
Published in Autophagy (03-04-2017)“…During the process of oxidative phosphorylation, protons are pumped into the mitochondrial intermembrane space to establish a mitochondrial membrane potential…”
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Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region
Published in Oncotarget (10-05-2016)“…Non-small cell lung cancer (NSCLC) cells often possess a hypermethylated Keap1 promoter, which decreases Keap1 mRNA and protein expression levels, thus…”
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Fragmentation level determines mitochondrial damage response and subsequently the fate of cancer cells exposed to carbon ions
Published in Radiotherapy and oncology (01-10-2018)“…Although mitochondria are known to play an important role in radiation-induced cellular damage response, the mechanisms of how radiation elicits mitochondrial…”
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Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities
Published in Cell death discovery (20-07-2021)“…Studies of radiation interaction with tumor cells often take apoptosis as the desired results. However, mitotic catastrophe and senescence are also promoted by…”
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Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy
Published in Experimental hematology & oncology (27-07-2023)“…Ferroptosis is a regulated cell death mode triggered by iron-dependent toxic membrane lipid peroxidation. As a novel cell death modality that is…”
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Genistein enhances the radiosensitivity of breast cancer cells via G₂/M cell cycle arrest and apoptosis
Published in Molecules (Basel, Switzerland) (24-10-2013)“…The aim of the present study was to investigate the radiosensitizing effect of genistein, and the corresponding mechanisms of action on breast cancer cells…”
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Comprehensive analysis of the prognostic value and immunological role of IDO1 gene in pan-cancer
Published in European journal of medical research (27-03-2024)“…It has been demonstrated that IDO1, a target of immune checkpoint inhibition, functions as an oncogene in the majority of human malignancies. IDO1's function…”
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Role of autophagy in high linear energy transfer radiation‐induced cytotoxicity to tumor cells
Published in Cancer science (01-07-2014)“…Heavy‐ion radiotherapy has a potential advantage over conventional radiotherapy due to improved dose distribution and a higher biological effectiveness in…”
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Study of COD Removal from the Waste Drilling Fluid and Its Application Chad Oilfield
Published in Journal of water chemistry and technology (2021)“…The increase in the demand for oil and gas in various countries will lead to an increase in the number of oil and gas drilling and the production of waste…”
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Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure
Published in Scientific reports (22-12-2015)“…To explore charged particle radiation-induced long-term hippocampus damage, we investigated the expression of autophagy and antioxidant Nrf2 signaling-related…”
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Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta‐analysis
Published in Cancer medicine (Malden, MA) (01-12-2021)“…Background and aims The existing evidence has indicated that hyperthermia ablation (HA) and HA combined with transarterial chemoembolization (HATACE) are the…”
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Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection
Published in Antioxidants (01-02-2023)“…Radiotherapy (RT) is one of the most effective cancer treatments. However, successful radiation protection for normal tissue is a clinical challenge. Our…”
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A Facile Approach to Tune the Electrical and Thermal Properties of Graphene Aerogels by Including Bulk MoS2
Published in Nanomaterials (Basel, Switzerland) (01-12-2017)“…Graphene aerogels (GAs) have attracted extensive interest in diverse fields, owing to their ultrahigh surface area, low density and decent electrical…”
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Carbon Ion Radiotherapy Acts as the Optimal Treatment Strategy for Unresectable Liver Cancer During the Coronavirus Disease 2019 Crisis
Published in Frontiers in public health (09-12-2021)“…The coronavirus disease 2019 (COVID-19) pandemic has greatly disrupted the normal treatment of patients with liver cancer and increased their risk of death…”
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Caspase-9: structure, mechanisms and clinical application
Published in Oncotarget (04-04-2017)“…As the most intensively studied initiator caspase, caspase-9 is a key player in the intrinsic or mitochondrial pathway which is involved in various stimuli,…”
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