Search Results - "Liu, Xinran N"
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Seipin is required for converting nascent to mature lipid droplets
Published in eLife (26-08-2016)“…How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood. Using and human cells, we show here that seipin, an ER protein…”
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Journal Article -
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FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis
Published in The Journal of cell biology (05-10-2020)“…The endoplasmic reticulum is a cellular hub of lipid metabolism, coordinating lipid synthesis with continuous changes in metabolic flux. Maintaining ER lipid…”
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Journal Article -
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Tissue-specific modifier alleles determine Mertk loss-of-function traits
Published in eLife (15-08-2022)“…Knockout (KO) mouse models play critical roles in elucidating biological processes behind disease-associated or disease-resistant traits. As a presumed…”
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Journal Article