Search Results - "Liu, Xianglan"
-
1
White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Adipocyte Axis
Published in Cell metabolism (07-09-2011)“…Living in an enriched environment with complex physical and social stimulation leads to improved cognitive and metabolic health. In white fat, enrichment…”
Get full text
Journal Article -
2
Knockdown of NEAT1 induces tolerogenic phenotype in dendritic cells by inhibiting activation of NLRP3 inflammasome
Published in Theranostics (01-01-2019)“…Tolerogenic dendritic cells (tol-DCs) play essential roles in immune-related diseases and induce immune tolerance by shaping T-cell responses. Accumulating…”
Get full text
Journal Article -
3
Environmental and Genetic Activation of a Brain-Adipocyte BDNF/Leptin Axis Causes Cancer Remission and Inhibition
Published in Cell (09-07-2010)“…Cancer is influenced by its microenvironment, yet broader, environmental effects also play a role but remain poorly defined. We report here that mice living in…”
Get full text
Journal Article -
4
The Long Noncoding RNA MALAT1 Induces Tolerogenic Dendritic Cells and Regulatory T Cells via miR155/Dendritic Cell-Specific Intercellular Adhesion Molecule-3 Grabbing Nonintegrin/IL10 Axis
Published in Frontiers in immunology (13-08-2018)“…By shaping T cell immunity, tolerogenic dendritic cells (tDCs) play critical roles in the induction of immune tolerance after transplantation. However, the…”
Get full text
Journal Article -
5
Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ1 signaling pathway in diabetic atherosclerosis
Published in Molecular medicine (Cambridge, Mass.) (21-01-2022)“…Abstract Background The unique mechanism of diabetic atherosclerosis has been a central research focus. Previous literature has reported that the inflammatory…”
Get full text
Journal Article -
6
Variability in Plasma Lipids Between Intensive Statin Therapy and Conventional-Dose Statins Combined with Ezetimibe Therapy in Patients with Coronary Atherosclerosis Disease
Published in International Heart Journal (30-09-2023)“…Dyslipidemia has been widely recognized as a significant risk factor for coronary atherosclerosis disease (CAD). In fact, lipid variability has emerged as a…”
Get full text
Journal Article -
7
Programmed Cell Death-4 Deficiency Prevents Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-12-2013)“…Programmed cell death-4 (PDCD4), a selective protein translation inhibitor, has shown proinflammatory effect in some inflammatory diseases, but its roles in…”
Get full text
Journal Article -
8
New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography
Published in BMC cardiovascular disorders (12-11-2022)“…Abstract Objective Vulnerable plaques with fibrous cap thickness (FCT) of ≤65 μm are prone to rupture and/or thrombosis. However, plaques with FCT > 65 μm…”
Get full text
Journal Article -
9
Incidence and Predictors of Neoatherosclerosis in Patients with Early In-Stent Restenosis Determined Using Optical Coherence Tomography
Published in International Heart Journal (29-09-2020)“…In-stent restenosis (ISR) still exists after drug-eluting stent (DES) implantation, even up to one year. The incidence and risk factors for neoatherosclerosis…”
Get full text
Journal Article -
10
Environmental enrichment exerts sex-specific effects on emotionality in C57BL/6J mice
Published in Behavioural brain research (01-01-2011)“…▶ Environmental enrichment affects affective behavior in C57BL/6J adolescent mice. ▶ Physical environmental enrichment reduces anxiety in male mice. ▶ Physical…”
Get full text
Journal Article -
11
High Levels of Circulating MicroRNA-3667-3p Are Associated with Coronary Plaque Erosion in Patients with ST-Segment Elevation Myocardial Infarction
Published in International Heart Journal (27-09-2019)“…Plaque erosion (PE) is a significant substrate of acute coronary thrombosis. An improved ability to distinguish plaque phenotype in vivo among patients with…”
Get full text
Journal Article -
12
Joint Multiple Fine-grained feature for Vehicle Re-Identification
Published in Array (New York) (01-07-2022)“…The process of recognizing the same vehicle in different scenes is called vehicle re-identification. However, due to the different locations of the…”
Get full text
Journal Article -
13
Controlled Transformation of Liquid Metal Microspheres in Aqueous Solution Triggered by Growth of GaOOH
Published in ACS omega (08-03-2022)“…Liquid metals (LMs) are playing an increasingly important role in the fields of flexible devices, electronics, and thermal management due to their low melting…”
Get full text
Journal Article -
14
Molecular therapy of obesity and diabetes by a physiological autoregulatory approach
Published in Nature medicine (01-04-2009)“…Hypothalamic brain-derived neurotrophic factor (BDNF) is a key element in the regulation of energy balance. Here we investigated the therapeutic efficacy of…”
Get full text
Journal Article -
15
Targeting Visceral Fat by Intraperitoneal Delivery of Novel AAV Serotype Vector Restricting Off-Target Transduction in Liver
Published in Molecular therapy. Methods & clinical development (15-09-2017)“…It is challenging to genetically manipulate fat in adults. We demonstrate that intraperitoneal (i.p.) injection of an engineered adeno-associated virus (AAV)…”
Get full text
Journal Article -
16
Mesenchymal-Epithelial Transition Exon 14 Skipping Mutation and Amplification in 5,008 Patients With Lung Cancer
Published in Frontiers in oncology (30-09-2021)“…Lung cancer is a major health concern worldwide because of its increasing incidence and mortality. This study aimed to clarify the association between…”
Get full text
Journal Article -
17
-
18
Association between the variability of non-high-density lipoprotein cholesterol and the neutrophil-to-lymphocyte ratio in patients with coronary heart disease
Published in Frontiers in cardiovascular medicine (22-11-2023)“…Lowering lipid variability may be a potential strategy for improving the inflammatory state in patients with coronary heart disease (CHD). This study…”
Get full text
Journal Article -
19
MicroRNA let-7i regulates dendritic cells maturation targeting interleukin-10 via the Janus kinase 1–signal transducer and activator of transcription 3 signal pathway subsequently induces prolonged cardiac allograft survival in rats
Published in The Journal of heart and lung transplantation (01-03-2016)“…Background In this study, we investig1ated whether microRNA let-7i regulates dendric cell maturation targeting interleukin-10 (IL-10) via the Janus kinase…”
Get full text
Journal Article -
20
Administration of Interleukin-35-Conditioned Autologous Tolerogenic Dendritic Cells Prolong Allograft Survival After Heart Transplantation
Published in Cellular physiology and biochemistry (01-01-2018)“…Abstract Background/Aims: IL-35, a powerful suppressor of inflammation and autoimmunity, is primarily secreted by regulatory T cells (Tregs) and can, in turn,…”
Get full text
Journal Article