Search Results - "Liu, Xi Qiu"

Biological responses to nanomaterials: understanding nano-bio effects on cell behaviors by Liu, Xi-Qiu, Tang, Rui-Zhi

“…The unique properties of nanomaterials in drug delivery and tissue engineering have captured a great deal of attention as experimental tools in bioimaging,…”
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Biophysical cues of in vitro biomaterials-based artificial extracellular matrix guide cancer cell plasticity by Tang, Rui-Zhi, Liu, Xi-Qiu

“…Clinical evidence supports a role for the extracellular matrix (ECM) in cancer plasticity across multiple tumor types. The lack of in vitro models that…”
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Multiple Functional Hyperbranched Poly(amido amine) Nanoparticles: Synthesis and Application in Cell Imaging by Yang, Wen, Pan, Cai-Yuan, Liu, Xi-Qiu, Wang, Jun

“…The hyperbranched poly(amido amine) nanoparticles (HPAMAM NPs) with multiple functions, such as biodegradability, autofluorescence, and specific affinity, were…”
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Functionalized micelles from block copolymer of polyphosphoester and poly(ɛ-caprolactone) for receptor-mediated drug delivery by Wang, Yu-Cai, Liu, Xi-Qiu, Sun, Tian-Meng, Xiong, Meng-Hua, Wang, Jun

“…Cellular specific micellar systems from functional amphiphilic block copolymers are attractive for targeted intracellular drug delivery. In this study, we…”
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Polymeric-Micelle-Based Nanomedicine for siRNA Delivery by Liu, Xi-Qiu, Sun, Chun-Yang, Yang, Xian-Zhu, Wang, Jun

“…Small interfering RNAs (siRNAs) are a rapidly emerging class of innovative nucleic acid medicines for the treatment of diseases such as cancer. However,…”
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Layer-by-Layer Assemblies for Cancer Treatment and Diagnosis by Liu, Xi Qiu, Picart, Catherine

“…The layer‐by‐layer (LbL) technique was introduced in the early 1990s. Since then, it has undergone a series of technological developments, making it possible…”
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Fabrication of a Coculture Organoid Model in the Biomimetic Matrix of Alginate to Investigate Breast Cancer Progression in a TAMs-Leading Immune Microenvironment by Xu, Nian-Yuan, Li, Jun, Wang, Mei-Ling, Chen, Xue-Yu, Tang, Ruizhi, Liu, Xi-Qiu

“…The current research models of breast cancer are usually limited in their capacity to recapitulate the tumor microenvironment in vitro. The lack of an…”
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Therapeutic Delivery of siRNA Silencing HIF‑1 Alpha with Micellar Nanoparticles Inhibits Hypoxic Tumor Growth by Liu, Xi-Qiu, Xiong, Meng-Hua, Shu, Xiao-Ting, Tang, Rui-Zhi, Wang, Jun

“…The particular characteristics of the tumor microenvironment have the potential to strongly promote tumor growth, metastasis and angiogenesis and induce drug…”
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Substrate Stiffness Combined with Hepatocyte Growth Factor Modulates Endothelial Cell Behavior by Chang, Hao, Liu, Xi-qiu, Hu, Mi, Zhang, He, Li, Bo-chao, Ren, Ke-feng, Boudou, Thomas, Albiges-Rizo, Corinne, Picart, Catherine, Ji, Jian

“…Endothelial cells (ECs) play a crucial role in regulating various physiological and pathological processes. The behavior of ECs is modulated by physical (e.g.,…”
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Targeted Delivery of Antisense Inhibitor of miRNA for Antiangiogenesis Therapy Using cRGD-Functionalized Nanoparticles by Liu, Xi-Qiu, Song, Wen-Jing, Sun, Tian-Meng, Zhang, Pei-Zhuo, Wang, Jun

“…MiRNAs are viable therapeutic targets for cancer therapy, but the targeted delivery of miRNA or its anti-miRNA antisense oligonucleotides (AMOs) remains a…”
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Immobilized Transforming Growth Factor-Beta 1 in a Stiffness-Tunable Artificial Extracellular Matrix Enhances Mechanotransduction in the Epithelial Mesenchymal Transition of Hepatocellular Carcinoma by Tang, Rui-Zhi, Gu, Sai-Sai, Chen, Xin-Ting, He, Li-Jie, Wang, Kai-Ping, Liu, Xi-Qiu

“…Cancer progression is regulated by multiple factors of extracellular matrix (ECM). Understanding how cancer cells integrate multiple signaling pathways to…”
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Physical confinement in alginate cryogels determines macrophage polarization to a M2 phenotype by regulating a STAT-related mRNA transcription pathway by Liu, Zhen-Zhen, Xu, Nian-Yuan, Wang, Mei-Ling, Tang, Rui-Zhi, Liu, Xi-Qiu

“…The immunologic response is considered to play a pivotal role in the application of biomaterial implants, and intrinsic properties of biomaterials can…”
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Recent Developments in Layer‐by‐Layer Assembly for Drug Delivery and Tissue Engineering Applications by Borges, João, Zeng, Jinfeng, Liu, Xi Qiu, Chang, Hao, Monge, Claire, Garot, Charlotte, Ren, Ke‐feng, Machillot, Paul, Vrana, Nihal E., Lavalle, Philippe, Akagi, Takami, Matsusaki, Michiya, Ji, Jian, Akashi, Mitsuru, Mano, João F., Gribova, Varvara, Picart, Catherine

“…Surfaces with biological functionalities are of great interest for biomaterials, tissue engineering, biophysics, and for controlling biological processes. The…”
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A 3D-printed scaffold-based osteosarcoma model allows to investigate tumor phenotypes and pathogenesis in an in vitro bone-mimicking niche by Wang, Mei-Ling, Xu, Nian-Yuan, Tang, Rui-Zhi, Liu, Xi-Qiu

“…[Display omitted] •Similar mechanical and structural properties as cortical bones.•Recapitulating osteosarcoma phenotypes in morphology, proliferation,…”
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Localized delivery of chemokine for in vitro manipulation of hepatocellular carcinoma cell behaviors during the epithelial–mesenchymal transition by Liu, Xi-Qiu, Tang, Rui-Zhi

“…Hepatocellular carcinoma develops within an altered mechanical and biochemical environment. The chemokine C–X–C motif chemokine ligand 12 plays an important…”
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Biomimetic Matrix Stiffness Modulates Hepatocellular Carcinoma Malignant Phenotypes and Macrophage Polarization through Multiple Modes of Mechanical Feedbacks by Liu, Xi-Qiu, Chen, Xin-Ting, Liu, Zhen-Zhen, Gu, Sai-Sai, He, Li-Jie, Wang, Kai-Ping, Tang, Rui-Zhi

“…The extracellular matrix (ECM) stiffening is an important sign of local microenvironment change, which is considered as a hallmark of many diseases including…”
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Brush-shaped polycation with poly(ethylenimine)- b-poly(ethylene glycol) side chains as highly efficient gene delivery vector by Liu, Xi-Qiu, Du, Jin-Zhi, Zhang, Chu-Pei, Zhao, Fang, Yang, Xian-Zhu, Wang, Jun

“…A brush-shaped polymer PHEMA- g-(PEI- b-PEG) with poly(2-hydroxyethyl methacrylate) (PHEMA) backbone and linear poly(ethylenimine)- b-poly(ethylene glycol)…”
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In Vitro Osteosarcoma Models Based on 3D-Printed Composite Scaffolds to Reveal Cellular Responses, Molecular Mechanisms and Predictive Biomarkers by Wang, Mei-Ling, Chen, Xue-Yu, Xu, Nian-Yuan, Li, Jun, Tang, Ruizhi, Liu, Xi-Qiu

“…Osteosarcoma (OS) is the most diagnosed bone tumor in children, and current in vitro methods (2D cell culture and tumor spheroids) cannot appropriately reflect…”
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Biomaterial-enabled delivery of SDF-1α at the ventral side of breast cancer cells reveals a crosstalk between cell receptors to promote the invasive phenotype by Liu, Xi Qiu, Fourel, Laure, Dalonneau, Fabien, Sadir, Rabia, Leal, Salome, Lortat-Jacob, Hugues, Weidenhaupt, Marianne, Albiges-Rizo, Corinne, Picart, Catherine

“…Abstract The SDF-1α chemokine (CXCL12) is a potent bioactive chemoattractant known to be involved in hematopoietic stem cell homing and cancer progression. The…”
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The effect of delivering the chemokine SDF-1α in a matrix-bound manner on myogenesis by Dalonneau, Fabien, Liu, Xi Qiu, Sadir, Rabia, Almodovar, Jorge, Mertani, Hichem C, Bruckert, Franz, Albiges-Rizo, Corinne, Weidenhaupt, Marianne, Lortat-Jacob, Hugues, Picart, Catherine

“…Abstract Several chemokines are important in muscle myogenesis and in the recruitment of muscle precursors during muscle regeneration. Among these, the SDF-1α…”
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