Search Results - "Liu, Si‐Yang"
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An Enzyme‐Engineered Nonporous Copper(I) Coordination Polymer Nanoplatform for Cuproptosis‐Based Synergistic Cancer Therapy
Published in Advanced materials (Weinheim) (01-10-2022)“…Cuproptosis, a newly identified form of regulated cell death that is copper‐dependent, offers great opportunities for exploring the use of copper‐based…”
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Emerging evidence and treatment paradigm of non-small cell lung cancer
Published in Journal of hematology and oncology (17-04-2023)“…Research on biomarker-driven therapy and immune check-point blockade in non-small cell lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical…”
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Electrochemical Exfoliation of Pillared‐Layer Metal–Organic Framework to Boost the Oxygen Evolution Reaction
Published in Angewandte Chemie International Edition (16-04-2018)“…Two‐dimensional (2D) materials and ultrathin nanosheets are advantageous for elevating the catalysis performance and elucidating the catalysis mechanism of…”
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Potential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung Adenocarcinoma
Published in Clinical cancer research (15-06-2017)“…Although clinical studies have shown promise for targeting programmed cell death protein-1 (PD-1) and ligand (PD-L1) signaling in non-small cell lung cancer…”
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Ultrathin 2D Copper(I) 1,2,4‐Triazolate Coordination Polymer Nanosheets for Efficient and Selective Gene Silencing and Photodynamic Therapy
Published in Advanced materials (Weinheim) (01-05-2021)“…Gene silencing holds promise for cancer therapeutics because of its potential to inhibit genes involved in tumor development. However, gene silencing is still…”
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Longitudinal Undetectable Molecular Residual Disease Defines Potentially Cured Population in Localized Non-Small Cell Lung Cancer
Published in Cancer discovery (06-07-2022)“…The efficacy and potential limitations of molecular residual disease (MRD) detection urgently need to be fully elucidated in a larger population of non-small…”
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Flexible Cuprous Triazolate Frameworks as Highly Stable and Efficient Electrocatalysts for CO2 Reduction with Tunable C2H4/CH4 Selectivity
Published in Angewandte Chemie International Edition (11-07-2022)“…Cu‐based metal–organic frameworks have attracted much attention for electrocatalytic CO2 reduction, but they are generally instable and difficult to control…”
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Targeted Therapy in Early Stage Non-small Cell Lung Cancer
Published in Current treatment options in oncology (01-09-2022)“…Opinion statement Tyrosine kinase inhibitors (TKIs) have dramatically improved tumor response rates and survival benefits in advanced oncogenic non-small-cell…”
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Isolation of Structurally Heterogeneous TCR‐CD3 Extracellular Vesicle Subpopulations Using Caliper Strategy
Published in Angewandte Chemie International Edition (24-04-2023)“…Cells in different states can release diverse types of extracellular vesicles (EVs) that participate in intracellular communication or pathological processes…”
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Photoluminescent Metal–Organic Frameworks for Gas Sensing
Published in Advanced science (01-07-2016)“…Luminescence of porous coordination polymers (PCPs) or metal–organic frameworks (MOFs) is sensitive to the type and concentration of chemical species in the…”
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Perioperative targeted therapy for oncogene-driven NSCLC
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2022)“…•Targeted therapy has stepped into the perioperative treatment setting for oncogenic NSCLC.•The role of adjuvant chemotherapy, surrogate endpoints, and…”
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A smartphone-assisted “all-in-one” paper chip for one-pot noninvasive detection of salivary glucose level
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-07-2023)“…[Display omitted] •The chromogenic paper chip was facilely prepared by one-pot synthesis.•The “all-in-one” strategy fundamentally improves the stability and…”
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Gefitinib Versus Vinorelbine Plus Cisplatin as Adjuvant Treatment for Stage II-IIIA (N1-N2) EGFR-Mutant NSCLC: Final Overall Survival Analysis of CTONG1104 Phase III Trial
Published in Journal of clinical oncology (01-03-2021)“…ADJUVANT-CTONG1104 (ClinicalTrials.gov identifier: NCT01405079), a randomized phase III trial, showed that adjuvant gefitinib treatment significantly improved…”
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Genomic signatures define three subtypes of EGFR-mutant stage II–III non-small-cell lung cancer with distinct adjuvant therapy outcomes
Published in Nature communications (08-11-2021)“…The ADJUVANT study reported the comparative superiority of adjuvant gefitinib over chemotherapy in disease-free survival of resected EGFR -mutant stage II–IIIA…”
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EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancer
Published in Oncoimmunology (02-11-2017)“…Patients with EGFR mutations showed unfavorable response to programmed cell death-1 (PD-1) blockade immunotherapy in non-small cell lung cancer (NSCLC). Yet…”
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Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients
Published in Cancer cell (09-10-2023)“…The value of circulating tumor DNA (ctDNA) during chemoradiotherapy (CRT) remains unclear but is critical for detecting molecular residual disease (MRD). In…”
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In Situ Enzyme Immobilization with Oxygen‐Sensitive Luminescent Metal–Organic Frameworks to Realize “All‐in‐One” Multifunctions
Published in Chemistry : a European journal (11-04-2019)“…Metal–organic frameworks (MOFs) for enzyme immobilization have already shown superior tunable and designable characteristics, however, their diverse responsive…”
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A Noble-Metal-Free Porous Coordination Framework with Exceptional Sensing Efficiency for Oxygen
Published in Angewandte Chemie International Edition (09-12-2013)“…Light material: By virtue of the unique framework structure and very high oxygen permeability, a noble‐metal‐free, highly fluorescent, porous coordination…”
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Neoadjuvant Camrelizumab for Non-Small Cell Lung Cancer: A Retrospective Multicenter, Real-World Study (CTONG2004)
Published in Cancer Immunology, Immunotherapy (01-07-2023)“…Background Camrelizumab has shown encouraging efficacy in advanced non-small cell lung cancer (NSCLC), either as monotherapy or combined with chemotherapy…”
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Specific TCR profiles predict clinical outcome of adjuvant EGFR-TKIs for resected EGFR-mutant non-small cell lung cancer
Published in Biomarker research (07-03-2023)“…ADJUVANT-CTONG1104 reported a favorable survival outcome from adjuvant gefitinib treatment over chemotherapy in EGFR-mutant non-small cell lung cancer (NSCLC)…”
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