Search Results - "Liu, Shien"

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening by Meng, Fanwang, Cheng, Sufang, Ding, Hong, Liu, Shien, Liu, Yan, Zhu, Kongkai, Chen, Shijie, Lu, Junyan, Xie, Yiqian, Li, Linjuan, Liu, Rongfeng, Shi, Zhe, Zhou, Yu, Liu, Yu-Chih, Zheng, Mingyue, Jiang, Hualiang, Lu, Wencong, Liu, Hong, Luo, Cheng

“…Histone methyltransferases are involved in various biological functions, and these methylation regulating enzymes’ abnormal expression or activity has been…”
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Oscillation Modes of Weld Pool in Stationary GTA Welding Using Structure Laser Method by Wu, Xingpei, Huang, Jiankang, He, Jing, Liu, Shien, Liu, Guangyin, Fan, Ding

“…Researchers have recently attempted to monitor pool oscillations using the three-dimensional laser vision method. However, the deficiency of simulation…”
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Systemic evolutionary chemical space exploration for drug discovery by Lu, Chong, Liu, Shien, Shi, Weihua, Yu, Jun, Zhou, Zhou, Zhang, Xiaoxiao, Lu, Xiaoli, Cai, Faji, Xia, Ning, Wang, Yikai

“…Chemical space exploration is a major task of the hit-finding process during the pursuit of novel chemical entities. Compared with other screening…”
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Brain areas activated by uncertain reward-based decision-making in healthy volunteers by Guo, Zongjun, Chen, Juan, Liu, Shien, Li, Yuhuan, Sun, Bo, Gao, Zhenbo

“…Reward-based decision-making has been found to activate several brain areas, including the ven- trolateral prefronta~ lobe, orbitofrontal cortex, anterior…”
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Achieving outstanding strength-ductility matching in BCC light-weight high entropy alloys via high content ordered nanoprecipitates by Dou, Bang, Pan, Yu, Liu, Shien, Wang, Benpeng, Cheng, Bo, Wang, Liang, Sun, Shihai, Xue, Yunfei

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Arc deposition of wear resistant layer TiN on Ti6Al4V using simultaneous feeding of nitrogen and wire by Huang, Jiankang, Liu, Shien, Yu, Shurong, Yu, Xiaoquan, Chen, Huizi, Fan, Ding

“…As an admirable surface improvement method, arc surface cladding has been widely used in various fields. The surface properties of titanium alloy were improved…”
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Precipitation suppression of refractory high-entropy alloys at intermediate temperature via adding oxygen by Cui, Jiaxiang, Dou, Bang, Liu, Shien, Zhou, Jingyan, Cui, Ning, Sun, Shihai, Cai, Hongnian, Wang, Liang, Xue, Yunfei

“…Due to the excellent mechanical properties, TiZrNb-based refractory high entropy alloys (RHEAs) show great potential application prospects in aviation,…”
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The microstructures and corrosion behavior of cladding layer on Ti-6Al-4V alloy using arc deposition with Ar and CO2 mixed shield gas by Huang, Jiankang, Liu, Shien, Wu, Lijian, Yu, Shurong, Yu, Xiaoquan, Yuan, Wen, Liao, Yiping, Fan, Ding

“…The surface modification of Ti6Al4V in biomedicine aims at the regeneration and healing of bones. It prolongs the service life, which is the basic…”
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Modulus-mismatch strategy optimized lightweight refractory high-entropy alloys for superior synergy of mechanical properties and thermostability by Dou, Bang, Cui, Jiaxiang, Guo, Rong, Liu, Shien, Zhang, Tianrui, Chen, Songshen, Li, Bolun, Wang, Xutao, Wang, Benpeng, Sun, Shihai, Wang, Liang, Xue, Yunfei

“…Lightweight refractory high-entropy alloys (LRHEAs) have received significant attention due to their excellent strength-plasticity matching. Generally, its…”
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Grain refinement induced dynamic plasticity improvement in lightweight high entropy alloys by Dou, Bang, Zhang, Yufei, Chen, Anhong, Cui, Jiaxiang, Li, Bolun, Chen, Songshen, Li, Yuqi, Liu, Shien, Wang, Xutao, Wang, Benpeng, Sun, Shihai, Wang, Liang, Xue, Yunfei

“…Lightweight high-entropy alloys (LHEAs) have gained significant attention due to their exceptional mechanical properties. Understanding the mechanical…”
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Microstructure and performances of dissimilar joints between 12Cr2Mo1R steel and 06Cr18Ni11Ti austenitic stainless steel joined by AA-TIG welding by Zhang, Jianxiao, Huang, Yanqin, Fan, Ding, Zhao, Jinlong, Huang, Jiankang, Yu, Xiaoquan, Liu, Shien

“…[Display omitted] •12Cr2Mo1R and 06Cr18Ni11Ti dissimilar steels are joined by AA-TIG welding, and the weld seam is formed well.•Pre-edge surfacing on the side…”
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Microstructure, Mechanical Performance, and Corrosion Behavior of Electron Beam Welded Thick Incoloy 825 Joints by Liu, Shien, Huang, Jiankang, Zhang, Jianxiao, Yu, Xiaoquan, Fan, Ding

“…This work mainly studies the microstructure and mechanical properties of Incoloy 825 electron beam welded joints at different temperatures along with their…”
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Simulation and control of metal droplet transfer in bypass coupling wire arc additive manufacturing by Huang, Jiankang, Guan, Zhichen, Yu, Shurong, Yu, Xiaoquan, Yuan, Wen, Liu, Shien, Fan, Ding

“…The influences of bypass current and wire feed speed are utilized to change the metal droplet transfer mode for bypass coupling wire-arcing additive…”
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Process of welding-brazing and interface analysis of lap joint Ti-6Al-4V and aluminum by plasma arc welding by Huang, Jiankang, Liu, Yulong, Liu, Shien, Guan, Zhichen, Yu, Xiaoquan, Wu, Haosheng, Yu, Shurong, Fan, Ding

“…[Display omitted] •The joint was realized by plasma arc welding with overlap which Ti-6Al-4V on the top of Al. The parameters are obtained.•The microstructure…”
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Cladding Inconel 625 on cast iron via bypass coupling micro-plasma arc welding by Huang, Jiankang, Liu, Shien, Yu, Shurong, An, Liang, Yu, Xiaoquan, Fan, Ding, Yang, Fuqian

“…There is great interest to deposit a layer of Inconel 625 nickel-base super-alloy on the surface of metallic substrate to increase the corrosion resistance for…”
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DNA Compatible Intermolecular Wittig Olefination for the Construction of α, β‑Unsaturated Carbonyl Compounds by An, Yu-Long, Li, Ke, Shen, Yanfang, Hong, Zibing, Chen, Linlin, Hu, Yujing, Zhou, Lichun, Wang, Disha, Shi, Xiaodong, Liu, Shien, Su, Wenji, Cui, Weiren, Kuai, Letian, Yang, Hongfang, Peng, Xuanjia

“…A robust DNA-compatible Wittig reaction mediated by PPh2CH3 has been validated for DNA-conjugated α-chloroacetamides with aldehydes and, alternatively,…”
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Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening by Zhang, Rukang, Wang, Jiang, Zhao, Liang, Liu, Shien, Du, Daohai, Ding, Hong, Chen, Shijie, Yue, Liyan, Liu, Yu-Chih, Zhang, Chenhua, Liu, Hong, Luo, Cheng

“…The histone acetyltransferases (HATs) in mammals include GCN5 N-acetyltransferases, the MOZ, YBF2, SAS2, and TIP60 proteins, and the orphan HATs. The males…”
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Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays by Shao, Zhiyuan, Xu, Pan, Xu, Wen, Li, Linjuan, Liu, Shien, Zhang, Rukang, Liu, Yu-Chih, Zhang, Chenhua, Chen, Shijie, Luo, Cheng

“…Novel DNMT3A inhibitor 40 was discovered via combining pharmacophore mapping and docking-based virtual screening, with in vitro IC50 of 46.5μM. [Display…”
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Magnetic resonance imaging and photothermal conversion properties of Gd‐C nanocomposites for interstitial lymphography by Yao, Yaqi, Suo, Lulu, Liu, Shien, Zeng, Wenxia, Shan, Jun, Zhang, Canying, Wu, Daxiong, Shang, Wei, Zhu, Haitao

“…Dual‐functional agents for magnetic resonance imaging (MRI) guided photothermal therapy (PTT) of lymph cancer are highly desired. Signal enhancement,…”
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Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine by Fu, Tianran, Liu, Liping, Yang, Qing-Lin, Wang, Yuxin, Xu, Pan, Zhang, Lin, Liu, Shien, Dai, Qing, Ji, Quanjiang, Xu, Guo-Liang, He, Chuan, Luo, Cheng, Zhang, Liang

“…The dynamic DNA methylation-demethylation process plays critical roles in gene expression control and cell development. The oxidation derivatives of…”
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