Search Results - "Liu, Ruiwu"

Rapid discovery of self-assembling peptides with one-bead one-compound peptide library by Yang, Pei-Pei, Li, Yi-Jing, Cao, Yan, Zhang, Lu, Wang, Jia-Qi, Lai, Ziwei, Zhang, Kuo, Shorty, Diedra, Xiao, Wenwu, Cao, Hui, Wang, Lei, Wang, Hao, Liu, Ruiwu, Lam, Kit S.

“…Self-assembling peptides have shown tremendous potential in the fields of material sciences, nanoscience, and medicine. Because of the vast combinatorial space…”
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Identification of osteogenic progenitor cell-targeted peptides that augment bone formation by Jiang, Min, Liu, Ruiwu, Liu, Lixian, Kot, Alexander, Liu, Xueping, Xiao, Wenwu, Jia, Junjing, Li, Yuanpei, Lam, Kit S., Yao, Wei

“…Activation and migration of endogenous mesenchymal stromal cells (MSCs) are critical for bone regeneration. Here, we report a combinational peptide screening…”
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Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass by Guan, Min, Yao, Wei, Liu, Ruiwu, Lam, Kit S, Nolta, Jan, Jia, Junjing, Panganiban, Brian, Meng, Liping, Zhou, Ping, Shahnazari, Mohammad, Ritchie, Robert O, Lane, Nancy E

“…Targeting mesenchymal stem cells (MSCs), progenitors of osteoblasts, to bone has been a long-standing goal but has had limited success so far. Here, Min Guan…”
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A novel lipophilic amiloride derivative efficiently kills chemoresistant breast cancer cells by Hu, Michelle, Liu, Ruiwu, Castro, Noemi, Loza Sanchez, Liliana, Rueankham, Lapamas, Learn, Julie A., Huang, Ruiqi, Lam, Kit S., Carraway, Kermit L.

“…Derivatives of the potassium-sparing diuretic amiloride are preferentially cytotoxic toward tumor cells relative to normal cells, and have the capacity to…”
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A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo by Shih, Tsung-Chieh, Liu, Ruiwu, Fung, Gabriel, Bhardwaj, Gaurav, Ghosh, Paramita M, Lam, Kit S

“…Through the one-bead two-compound (OB2C) ultra-high-throughput screening method, we discovered a new small-molecule compound LLS2 that can kill a variety of…”
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The C-reactive protein/albumin ratio, a validated prognostic score, predicts outcome of surgical renal cell carcinoma patients by Guo, Shengjie, He, Xiaobo, Chen, Qian, Yang, Guangwei, Yao, Kai, Dong, Pei, Ye, Yunlin, Chen, Dong, Zhang, Zhiling, Qin, Zike, Liu, Zhuowei, Xue, Yunfei, Zhang, Meng, Liu, Ruiwu, Zhou, Fangjian, Han, Hui

“…The preoperative C-reactive protein/Albumin (CRP/Alb) ratio has been shown to be valuable in predicting the prognosis of patients with certain cancers. The aim…”
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Extracellular Matrix Mimicking Nanofibrous Scaffolds Modified With Mesenchymal Stem Cell-Derived Extracellular Vesicles for Improved Vascularization by Hao, Dake, Swindell, Hila Shimshi, Ramasubramanian, Lalithasri, Liu, Ruiwu, Lam, Kit S, Farmer, Diana L, Wang, Aijun

“…The network structure and biological components of natural extracellular matrix (ECM) are indispensable for promoting tissue regeneration. Electrospun…”
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Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing by He, Siqi, Walimbe, Tanaya, Chen, Hongyuan, Gao, Kewa, Kumar, Priyadarsini, Wei, Yifan, Hao, Dake, Liu, Ruiwu, Farmer, Diana L., Lam, Kit S., Zhou, Jianda, Panitch, Alyssa, Wang, Aijun

“…Diabetic ischemic wound treatment remains a critical clinical challenge. Neovascularization plays a significant role in wound healing during all stages of the…”
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Congo red and thioflavin-T analogs detect Aβ oligomers by Maezawa, Izumi, Hong, Hyun-Seok, Liu, Ruiwu, Wu, Chun-Yi, Cheng, R. Holland, Kung, Mei-Ping, Kung, Hank F, Lam, Kit S, Oddo, Salvatore, LaFerla, Frank M, Jin, Lee-Way

“…Several small molecule ligands for amyloid-β (Aβ) fibrils deposited in brain have been developed to facilitate radiological diagnosis of Alzheimer's disease…”
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High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer by Xiao, Wenwu, Ma, Weijie, Wei, Sixi, Li, Qianping, Liu, Ruiwu, Carney, Randy P, Yang, Kevin, Lee, Joyce, Nyugen, Alan, Yoneda, Ken Y, Lam, Kit S, Li, Tianhong

“…α3β1 integrin is a promising cancer biomarker and drug target. We previously identified a 9-amino-acid cyclic peptide LXY30 for detecting α3β1 integrin on the…”
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Reversing bone loss by directing mesenchymal stem cells to bone by Yao, Wei, Guan, Min, Jia, Junjing, Dai, Weiwei, Lay, Yu‐An E., Amugongo, Sarah, Liu, Ruiwu, Olivos, David, Saunders, Mary, Lam, Kit S., Nolta, Jan, Olvera, Diana, Ritchie, Robert O., Lane, Nancy E.

“…Bone regeneration by systemic transplantation of mesenchymal stem cells (MSCs) is problematic due to the inability to control the MSCs' commitment, growth, and…”
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From Combinatorial Chemistry to Cancer-Targeting Peptides by Aina, Olulanu H, Liu, Ruiwu, Sutcliffe, Julie L, Marik, Jan, Pan, Chong-Xian, Lam, Kit S

“…Several monoclonal antibodies that target cell surface receptors have gained approval by the U.S. Food and Drug Administration and are widely used in the…”
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Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing by Song, Hengyue, Gao, Kewa, Hao, Dake, Li, Andrew, Liu, Ruiwu, Anggito, Bryan, Yin, Boyan, Jin, Qianyu, Dartora, Vanessa, Lam, Kit S, Smith, Lucas R, Panitch, Alyssa, Zhou, Jianda, Farmer, Diana L, Wang, Aijun

“…The lack of vascularization associated with deep burns delays the construction of wound beds, increases the risks of infection, and leads to the formation of…”
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Rapid Discovery of Illuminating Peptides for Instant Detection of Opioids in Blood and Body Fluids by Jafari, Shabnam, Thillier, Yann, Ajena, Yousif H, Shorty, Diedra, Li, Jiannan, Huynh, Jonathan S, Pan, Bethany Ming-Choi, Pan, Tingrui, Lam, Kit S, Liu, Ruiwu

“…The United States is currently experiencing an opioid crisis, with more than 47,000 deaths in 2017 due to opioid overdoses. Current approaches for opioid…”
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Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one- compound peptide libraries by Leung, Nicki YH, Wai, Christine YY, Ho, Marco HK, Liu, Ruiwu, Lam, Kit S, Wang, Jin Jun, Shu, Shang An, Chu, Ka Hou, Leung, Patrick SC

“…The one-bead-one-compound （OBOC） combinatorial peptide library is a powerful tool to identify ligand and receptor interactions. Here, we applied the OBOC…”
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A Novel Peptide-Based Encoding System for “One-Bead One-Compound” Peptidomimetic and Small Molecule Combinatorial Libraries by Liu, Ruiwu, Marik, Jan, Lam, Kit S

“…The “one-bead one-compound” (OBOC) combinatorial library method is highly efficient, especially when used with well-established on-bead binding or functional…”
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A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices by Hao, Dake, Lin, Jonathan, Liu, Ruiwu, Pivetti, Christopher, Yamashiro, Kaeli, Schutzman, Linda M., Sageshima, Junichiro, Kwong, Mimmie, Bahatyrevich, Nataliya, Farmer, Diana L., Humphries, Misty D., Lam, Kit S., Panitch, Alyssa, Wang, Aijun

“…Implantable vascular devices are widely used in clinical treatments for various vascular diseases. However, current approved clinical implantable vascular…”
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ITK inhibition for the targeted treatment of CTCL by Bustos-Villalobos, Itzel, Bergstrom, Jennifer Williams, Haigh, Nathan E, Luna, Jesus I, Mitra, Anupam, Marusina, Alina I, Merleev, Alexander A, Wang, Elizabeth A, Sukhov, Andrea, Sultani, Hawa, Liu, Ruiwu, Bhardwaj, Gaurav, Guo, Wenchang, Kung, Hsing-Jien, Lam, Kit S, Maverakis, Emanual

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A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects by Hao, Dake, Liu, Ruiwu, Fernandez, Tomas Gonzalez, Pivetti, Christopher, Jackson, Jordan Elizabeth, Kulubya, Edwin Samuel, Jiang, Hong-Jiang, Ju, Hai-Yang, Liu, Wen-Liang, Panitch, Alyssa, Lam, Kit S., Leach, J. Kent, Farmer, Diana L., Wang, Aijun

“…Significant progress has been made in designing bone materials capable of directing endogenous cells to promote vascularized bone regeneration. However,…”
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A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation by Jiang, Min, Liu, Lixian, Liu, Ruiwu, Lam, Kit S, Lane, Nancy E, Yao, Wei

“…Currently, there are no effective medications to reverse periodontal disease (PD)-induced bone loss. The objective of this study was to test a new anabolic…”
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