Search Results - "Liu, Rugao"

Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum by Chen, Xuesong, Lan, Xun, Roche, Ian, Liu, Rugao, Geiger, Jonathan D

“…The blood-brain barrier (BBB) is important physiologically. Pathologically, BBB disruption has been implicated in a wide spectrum of neurological disorders…”
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Manganese superoxide dismutase protects mouse cortical neurons from chronic intermittent hypoxia-mediated oxidative damage by Shan, Xiaoyang, Chi, Liying, Ke, Yan, Luo, Chun, Qian, Steven, Gozal, David, Liu, Rugao

“…Abstract Obstructive sleep apnea (OSA) syndrome has been recognized as a highly prevalent public health problem and is associated with major neurobehavioral…”
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GABAB Receptor Activation Inhibits Neuronal Excitability and Spatial Learning in the Entorhinal Cortex by Activating TREK-2 K+ Channels by Deng, Pan-Yue, Xiao, Zhaoyang, Yang, Chuanxiu, Rojanathammanee, Lalida, Grisanti, Laurel, Watt, John, Geiger, Jonathan D., Liu, Rugao, Porter, James E., Lei, Saobo

“…The entorhinal cortex (EC) is regarded as the gateway to the hippocampus and thus is essential for learning and memory. Whereas the EC expresses a high density…”
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Intermittent Hypoxia Is Associated with Oxidative Stress and Spatial Learning Deficits in the Rat by Row, Barry W, Liu, Rugao, Xu, Wei, Kheirandish, Leila, Gozal, David

“…In the adult rat, exposure to intermittent hypoxia (IH), such as occurs in sleep-disordered breathing, is associated with neurobehavioral impairments and…”
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Early Response of Endogenous Adult Neural Progenitor Cells to Acute Spinal Cord Injury in Mice by Ke, Yan, Chi, Liying, Xu, Renshi, Luo, Chun, Gozal, David, Liu, Rugao

“…Adult neural progenitor cells (NPCs) are an attractive source for functional replacement in neurodegenerative diseases and traumatic injury to the central…”
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Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease by Liu, Rugao, Lei, Joy X, Luo, Chun, Lan, Xun, Chi, Liying, Deng, Panyue, Lei, Saobo, Ghribi, Othman, Liu, Qing Yan

“…Abstract Though loss of function in CBP/p300, a family of CREB-binding proteins, has been causally associated with a variety of human neurological disorders,…”
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Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer’s disease-like transgenic (pPDGF-APPSw,Ind ) mice by Gan, Li, Qiao, Shuhong, Lan, Xun, Chi, Liying, Luo, Chun, Lien, Lindsey, Yan Liu, Qing, Liu, Rugao

“…Abstract Formation and accumulation of amyloid-beta (Aβ) plaques are associated with declined memory and other neurocognitive function in Alzheimer’s disease…”
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A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation by Liu, Qing Yan, Lei, Joy X, Sikorska, Marianna, Liu, Rugao

“…Alterations in multiple cellular pathways contribute to the development of chronic neurodegeneration such as a sporadic Alzheimer's disease (AD). These, in…”
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Enhanced De Novo Neurogenesis and Dopaminergic Neurogenesis in the Substantia Nigra of 1‐Methyl‐4‐phyenyl‐1,2,3,6‐Tetrahydropyridine‐Induced Parkinson's Disease‐Like Mice by Shan, Xiaoyang, Chi, Liying, Bishop, Michael, Luo, Chun, Lien, Lindsey, Zhang, Zheng, Liu, Rugao

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Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function by Gozal, David, Row, Barry W., Kheirandish, Leila, Liu, Rugao, Guo, Shang Z., Qiang, Fan, Brittian, Kenneth R.

“…Obstructive sleep apnea (OSA) is a frequent medical condition characterized by intermittent hypoxia (IH) during sleep, and is associated with neurodegenerative…”
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Structural remodeling of nucleus ambiguus projections to cardiac ganglia following chronic intermittent hypoxia in C57BL/6J mice by Lin, Min, Ai, Jing, Li, Lihua, Huang, Chenghui, Chapleau, Mark W., Liu, Rugao, Gozal, David, Wead, William B., Wurster, Robert D., Cheng, Zixi (Jack)

“…The baroreflex control of heart rate (HR) is reduced following chronic intermittent hypoxia (CIH). Since the nucleus ambiguus (NA) plays a key role in…”
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Temporal response of neural progenitor cells to disease onset and progression in amyotrophic lateral sclerosis-like transgenic mice by Chi, Liying, Gan, Li, Luo, Chun, Lien, Lindsey, Liu, Rugao

“…Regenerative medicine through neural stem cells (NSCs) or neural progenitor cells (NPCs) has been proposed as an alterative avenue for restoring neurological…”
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Nestin‐positive cells in the spinal cord: a potential source of neural stem cells by Xu, Renshi, Wu, Chengsi, Tao, Yuhui, Yi, Juan, Yang, Yunzhu, Zhang, Xiong, Liu, Rugao

“…Some literatures have reported neural precursor cells (NPCs) exist in spinal cord of adult mammal, however, the NPCs distribution feature in spinal cord of…”
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Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1‐mediated motor neuron cell death and increase amyotrophic lateral sclerosis‐like transgenic mouse survival by Liu, Rugao, Li, Baolin, Flanagan, Shawn W., Oberley, Larry W., Gozal, David, Qiu, Mengsheng

“…The molecular mechanisms of selective motor neuron degeneration in human amyotrophic lateral sclerosis (ALS) disease remain largely unknown and effective…”
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Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor by Liu, Rugao, Cai, Jun, Hu, Xuemei, Tan, Min, Qi, Yingchuan, German, Michael, Rubenstein, John, Sander, Maike, Qiu, Mengsheng

“…During early neural development, the Nkx6.1 homeodomain neural progenitor gene is specifically expressed in the ventral neural tube, and its activity is…”
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Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis by Liu, R, Althaus, J S, Ellerbrock, B R, Becker, D A, Gurney, M E

“…Mutations of the SOD1 gene encoding copper/zinc superoxide dismutase (CuZnSOD) cause an inherited form of amyotrophic lateral sclerosis. When expressed in…”
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Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-α by Liu, R, Li, B, Qiu, M

“…Accumulating evidence has suggested that cellular production of superoxide acts as an intracellular messenger to regulate gene expression and modulate cellular…”
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VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death by Li, Baolin, Xu, Wei, Luo, Chun, Gozal, David, Liu, Rugao

“…The increased oxidative stress induced by mutant SOD1 is associated with motor neuron degeneration in both human ALS and transgenic mice expressing mutant…”
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Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells by Liu, R, Oberley, T D, Oberley, L W

“…Overexpression of human manganese-containing superoxide dismutase (MnSOD) activity has been demonstrated to suppress malignancy in human melanoma and breast…”
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Selective Expression of Nkx-2.2 Transcription Factor in Chicken Oligodendrocyte Progenitors and Implications for the Embryonic Origin of Oligodendrocytes by Xu, Xiaohua, Cai, Jun, Fu, Hui, Wu, Rui, Qi, Yingchuan, Modderman, Geoffrey, Liu, Rugao, Qiu, Mengsheng

“…Recent studies have demonstrated that oligodendrocytes originate from the ventral region of the developing spinal cord. However, the precise neuroepithelial…”
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