Search Results - "Liu, Pinyan"
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The role of matrix stiffness in cancer stromal cell fate and targeting therapeutic strategies
Published in Acta biomaterialia (15-09-2022)“…The tumor microenvironment (TME) is a complex macromolecular network filled with a series of stromal cells. It plays an important role in tumorigenesis,…”
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Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential
Published in Stem cell research & therapy (26-07-2022)“…Cost-effective treatment strategies for liver fibrosis or cirrhosis are limited. Many clinical trials of stem cells for liver disease shown that stem cells…”
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Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils
Published in Journal of translational medicine (18-11-2023)“…The use of umbilical cord mesenchymal stem cells (UC-MSCs) is a burgeoning method for the treatment of liver cirrhosis. However, the secretory phenotype and…”
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Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma
Published in Journal of translational medicine (03-12-2022)“…Solid tumors are stiffer than their surrounding normal tissues; however, their interior stiffness is not uniform. Under certain conditions, cancer cells can…”
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A pancreas tumor derived organoid study: from drug screen to precision medicine
Published in Cancer cell international (27-07-2021)“…Pancreatic ductal adenocarcinoma (PDAC) one of the deadliest malignant tumor. Despite considerable progress in pancreatic cancer treatment in the past…”
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Organoid as a promising tool for primary liver cancer research: a comprehensive review
Published in Cell & bioscience (27-08-2024)“…Primary liver cancer (PLC) is one of the most common malignant gastrointestinal tumors worldwide. Limited by the shortage of liver transplantation donors and…”
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A scoping review of the clinical application of machine learning in data-driven population segmentation analysis
Published in Journal of the American Medical Informatics Association : JAMIA (18-08-2023)“…Abstract Objective Data-driven population segmentation is commonly used in clinical settings to separate the heterogeneous population into multiple relatively…”
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A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells
Published in The Journal of biological chemistry (01-07-2023)“…In normal tissue homeostasis, bidirectional communication between different cell types can shape numerous biological outcomes. Many studies have documented…”
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Pretreatment of UC-MSCs with IFN-[alpha]2 improves treatment of liver fibrosis by recruiting neutrophils
Published in Journal of translational medicine (18-11-2023)“…Background The use of umbilical cord mesenchymal stem cells (UC-MSCs) is a burgeoning method for the treatment of liver cirrhosis. However, the secretory…”
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Estimating individualized treatment effects using a risk-modeling approach: an application to epidural steroid injections for lumbar spinal stenosis
Published in Pain (Amsterdam) (01-04-2023)“…Conventional "1-variable-at-a-time" analyses to identify treatment effect modifiers are often underpowered and prone to false-positive results. This study used…”
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Federated and distributed learning applications for electronic health records and structured medical data: a scoping review
Published in Journal of the American Medical Informatics Association : JAMIA (17-11-2023)“…Abstract Objectives Federated learning (FL) has gained popularity in clinical research in recent years to facilitate privacy-preserving collaboration…”
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Federated and distributed learning applications for electronic health records and structured medical data: A scoping review
Published 14-04-2023“…Federated learning (FL) has gained popularity in clinical research in recent years to facilitate privacy-preserving collaboration. Structured data, one of the…”
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