Search Results - "Liu, Pingyu"

Targeting the untargetable KRAS in cancer therapy by Liu, Pingyu, Wang, Yijun, Li, Xin

“…RAS is one of the most well-known proto-oncogenes. Its gain-of-function mutations occur in approximately 30% of all human cancers. As the most frequently…”
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence by Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M., Tang, Hsin-Yao, Liu, Qin, Speicher, David W., Zhang, Rugang

“…Cyclic cGMP-AMP synthase (cGAS) is a pattern recognition cytosolic DNA sensor that is essential for cellular senescence. cGAS promotes inflammatory…”
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Epigenetic Basis of Cellular Senescence and Its Implications in Aging by Nacarelli, Timothy, Liu, Pingyu, Zhang, Rugang

“…Cellular senescence is a tumor suppressive response that has become recognized as a major contributor of tissue aging. Senescent cells undergo a stable…”
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m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype by Liu, Pingyu, Li, Fuming, Lin, Jianhuang, Fukumoto, Takeshi, Nacarelli, Timothy, Hao, Xue, Kossenkov, Andrew V., Simon, M. Celeste, Zhang, Rugang

“…Methyltransferase-like 3 (METTL3) and 14 (METTL14) are core subunits of the methyltransferase complex that catalyses messenger RNA N 6 -methyladenosine (m 6 A)…”
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Access to essential and innovative anti-cancer medicines: a longitudinal study in Nanjing, China by Cao, Zhaoliu, Wang, Lili, Ma, Rui, Hu, Yun, Bao, Baiyi, Liu, Xiaohua, Li, Mengyuan, Wang, Xiao, Liu, Pingyu, Li, Xin

“…To evaluate the availability, cost, affordability of anti-cancer medicines in Nanjing, Jiangsu. A longitudinal tracking investigation study was performed to…”
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De novo assembly of the seed transcriptome and search for potential EST-SSR markers for an endangered, economically important tree species: Elaeagnus mollis Diels by Liu, Yulin, Li, Siqiao, Wang, Yunying, Liu, Pingyu, Han, Wenjing

“…Seeds of Elaeagnus mollis (Elaeagnaceae) produce an edible oil and contain more vitamin E (Ve) than major oil-seed crops. Despite its economic value, there is…”
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Distinct functions of BMP4 during different stages of mouse ES cell neural commitment by Zhang, Kejing, Li, Lingyu, Huang, Chengyang, Shen, Chengyong, Tan, Fangzhi, Xia, Caihong, Liu, Pingyu, Rossant, Janet, Jing, Naihe

“…Bone morphogenetic protein (BMP) signaling plays a crucial role in maintaining the pluripotency of mouse embryonic stem cells (ESCs) and has negative effects…”
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Female perspective: the burden of Alzheimer's disease and other dementias in China from 1990 to 2019 and prediction of their prevalence up to 2044 by Meng, Wenxin, Xie, Jinping, Yuan, Ni, Liu, Pingyu, Yang, Fan, Jiang, Rong, Hua, Hui

“…Dementia is more prevalent in women than in men across the world, and sex differences are reflected in the burden of dementia borne by women and men. However,…”
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Research on Co-channel Interference Suppression Method for Passive Radar Based on the Jiont Processing of Primary and Reference Channels by Pingyu LIU, Xiaode LYU, Zhongsheng LIU, Hanliang ZHANG

“…The illuminators of passive radar based civil communication signals are densely distributed. As a result, the co-channel illuminator always interferes with the…”
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An exploration of the effect of Chinese herbal compound on the occurrence and development of large intestine cancer and intestinal flora by Liu, Pingyu, Ying, Jian, Guo, Xin, Tang, Xiaohui, Zou, Wenjuan, Wang, Tiantian, Xu, Xinyi, Zhao, Bin, Song, Na, Cheng, Jun

“…This study was conducted to observe the effect of Chinese herbal compound on the treatment of colon cancer using AOM/DSS-induced C57BL/6J colon cancer mice and…”
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N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance by Fukumoto, Takeshi, Zhu, Hengrui, Nacarelli, Timothy, Karakashev, Sergey, Fatkhutdinov, Nail, Wu, Shuai, Liu, Pingyu, Kossenkov, Andrew V., Showe, Louise C., Jean, Stephanie, Zhang, Lin, Zhang, Rugang

“…Abstract Despite the high initial response rates to PARP inhibitors (PARPi) in BRCA-mutated epithelial ovarian cancers (EOC), PARPi resistance remains a major…”
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Combined activin A/LiCl/Noggin treatment improves production of mouse embryonic stem cell-derived definitive endoderm cells by Li, Fuming, He, Zhiying, Li, Yangfang, Liu, Pingyu, Chen, Fei, Wang, Minjun, Zhu, Haiying, Ding, Xiaoyan, Wangensteen, Kirk J., Hu, Yiping, Wang, Xin

“…Induction of definitive endoderm (DE) cells is a prerequisite for the whole process of embryonic stem (ES) cells differentiating into hepatic or pancreatic…”
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m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype by Liu, Pingyu, Li, Fuming, Lin, Jianhuang, Fukumoto, Takeshi, Nacarelli, Timothy, Hao, Xue, Kossenkov, Andrew V., Simon, M. Celeste, Zhang, Rugang

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Photoacoustic ultrasound (PAUS)--reconstruction tomography by Kruger, R A, Liu, P, Fang, Y R, Appledorn, C R

“…The theoretical underpinnings of photoacoustic ultrasound (PAUS) reconstruction tomography are presented. A formal relationship between PAUS signals and the…”
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Spatial Features Acquisition for Airplane Target Detection in Hyperspectral Remote Sensing Using Virtual RGB Images by Liu, Pingyu, Wang, Xiaofei

“…Hyperspectral target detection (HTD) stands as a pivotal research area within hyperspectral image (HSI) processing. Airplane is challenging to detect as small…”
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Genome-wide analysis of histone acetylation dynamics during mouse embryonic stem cell neural differentiation by Liu, Pingyu, Dou, Xiaoyang, Peng, Guangdun, Han, Jing-Dong Jackie, Jing, Naihe

“…Epigenetic modification as an intrinsic fine-tune program cooperates with key transcription factors to regulate the cell fate determination. The histone…”
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ARID2 Deficiency Correlates with the Response to Immune Checkpoint Blockade in Melanoma by Fukumoto, Takeshi, Lin, Jianhuang, Fatkhutdinov, Nail, Liu, Pingyu, Somasundaram, Rajasekharan, Herlyn, Meenhard, Zhang, Rugang, Nishigori, Chikako

“…The SWI/SNF chromatin remodeler family includes the BAF and PBAF complexes. ARID2, encoding a PBAF complex subunit, is frequently mutated in melanoma…”
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N 6 -Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance by Fukumoto, Takeshi, Zhu, Hengrui, Nacarelli, Timothy, Karakashev, Sergey, Fatkhutdinov, Nail, Wu, Shuai, Liu, Pingyu, Kossenkov, Andrew V, Showe, Louise C, Jean, Stephanie, Zhang, Lin, Zhang, Rugang

“…Despite the high initial response rates to PARP inhibitors (PARPi) in -mutated epithelial ovarian cancers (EOC), PARPi resistance remains a major challenge…”
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MRE11 lactylation: a linker between Warburg effect and DNA repair by Liu, Pingyu, Ji, Hongbin, Li, Fuming

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Litter, root, and mycorrhiza manipulations and seasonal effects on soil physicochemical properties and microbial communities in a subtropical coniferous and broad-leaved mixed forest by Zhu, Liqin, Huang, Rongzhen, Guan, Hongzhi, Wang, Jinping, Huang, Zhijun, Fang, Huanying, Zou, Xianhua, Li, Jingkai, Liu, Pingyu

“…Organic inputs from aboveground litter and underground roots are an important factor affecting nutrient cycling in forest ecosystems. However, we still know…”
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