Search Results - "Liu, Pangyen"
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Regulatory Actions of Estrogen Receptor Signaling in the Cardiovascular System
Published in Frontiers in endocrinology (Lausanne) (10-01-2020)“…Premenopausal females have a lower incidence of death from cardiovascular disease (CVD) than male counterparts, supporting the notion that estrogen is…”
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Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A
Published in Diabetes (New York, N.Y.) (01-08-2018)“…Women gain weight and their diabetes risk increases as they transition through menopause; these changes can be partly reversed by hormone therapy. However, the…”
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Abstract 794: Endothelial Specific Ablation of Estrogen Receptor Alpha Rapid Signaling Revealed Exacerbated Vascular Remodeling Response
Published in Circulation research (02-08-2019)“…Abstract only Background: Estrogen exerts complex physiological effects via its rapid (non-genomic) and genomic actions. In particular, rapid signaling of…”
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Abstract 829: Endothelial Estrogen Non-nuclear Signaling Plays a Key Role in Anti-remodeling Effects via cGMP Signaling in Failing Heart
Published in Circulation research (02-08-2019)“…Abstract only Background: Estrogen plays a significant role in cardiovascular benefits. As one of its beneficial pathways, ERα non-nuclear signaling is known…”
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Endothelial estrogen - myocardial cGMP axis critically determines angiogenesis and cardiac performance during pressure-overload
Published in Cardiovascular research (11-09-2024)“…Estrogen exerts beneficial cardiovascular effects by binding to specific receptors on various cells to activate nuclear and non-nuclear actions. Estrogen…”
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Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and Is Essential to cGMP-PDE5 Inhibition Efficacy
Published in JACC. Basic to translational science (01-03-2020)“…[Display omitted] •The role of ERα non-nuclear signaling in female heart failure was investigated, using a novel mouse line in which ERα non-nuclear signaling…”
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