Search Results - "Liu, Luna"

Risk factors for early readmission to hospital in patients with malignancy-related ascites: a retrospective cohort study by Tian, Zhenhua, Huang, Zhilong, Guo, Yaqi, Zhao, Xiaolin, Liu, Luna, Yu, Chunxiao, Guan, Qingbo

“…Malignancy-related ascites (MRA) is a common serious complication of many advanced malignant tumors with high morbidity and mortality. The high hospital…”
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Association of Obesity based on Different Metabolic Status with Risk of Gout Occurrence in Patients: A National Study by Wang, Yanyan, Liu, Luna, Ma, Shizhan, Han, Junming, Wang, Zhixiang, Fan, Xiude, Hou, Xu

“…Obesity often co-exists with metabolic abnormalities, but the results of studies on the relationship between obesity, metabolic abnormalities and the risk of…”
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Characterization of intact antibody–drug conjugates from plasma/serum in vivo by affinity capture capillary liquid chromatography–mass spectrometry by Xu, Keyang, Liu, Luna, Saad, Ola M., Baudys, Jakub, Williams, Lara, Leipold, Douglas, Shen, Ben, Raab, Helga, Junutula, Jagath R., Kim, Amy, Kaur, Surinder

“…Antibody–drug conjugates (ADCs) are designed to facilitate the targeted delivery of cytotoxic drugs to improve their tumor fighting effects and minimize…”
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Evaluating the Impact of Obesity and Different Metabolic Statuses on the Prognosis of Hospitalized Patients with Inflammatory Bowel Disease: A Cohort Study by Wang, Yanyan, Liu, Luna, Han, Junming, Fan, Xiude, Guo, Qingling, Wu, Zhongming

“…Introduction: Obesity is associated with an increased risk of inflammatory bowel disease (IBD), whereas not all obese individuals have the same effect. In…”
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The health-care utilization and economic burden in patients with genetic skeletal disorders by Liu, Luna, Shi, Yingzhou, Fan, Xiude, Yao, Yangyang, Wu, Wanhong, Tian, Yang, Wu, Huixiao, Li, Zongyue, Wang, Yanzhou, Xu, Chao

“…Most genetic skeletal disorders (GSD) were complex, disabling and life-threatening without effective diagnostic and treatment methods. However, its impacts on…”
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High-Resolution Accurate-Mass Mass Spectrometry Enabling In-Depth Characterization of in Vivo Biotransformations for Intact Antibody-Drug Conjugates by He, Jintang, Su, Dian, Ng, Carl, Liu, Luna, Yu, Shang-Fan, Pillow, Thomas H, Del Rosario, Geoffrey, Darwish, Martine, Lee, Byoung-Chul, Ohri, Rachana, Zhou, Hongxiang, Wang, Xueji, Lu, Jiawei, Kaur, Surinder, Xu, Keyang

“…Antibody-drug conjugates (ADCs) represent a promising class of therapeutics for the targeted delivery of highly potent cytotoxic drugs to tumor cells to…”
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Correlation Between Gut Microbiota and Testosterone in Male Patients With Type 2 Diabetes Mellitus by Liu, Shuang, Cao, Ruying, Liu, Luna, Lv, Youyuan, Qi, Xiangyu, Yuan, Zhongshang, Fan, Xiude, Yu, Chunxiao, Guan, Qingbo

“…This study aimed at investigating the association between testosterone levels and gut microbiota in male patients with type 2 diabetes mellitus (T2DM) and…”
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Signal peptidase 21 suppresses cell proliferation, migration, and invasion via the PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma by Zhang, Na, Cao, Shiguang, Sun, Ruiying, Wang, Yibei, Liu, Luna, Wang, Wei, Meng, Xia

“…In a previous study, a total of 568 differentially expressed proteins including the signal peptidase SPC21 were identified from lung adenocarcinoma (LUAD) and…”
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The Fatty Liver Index, the Strongest Risk Factor for Low Testosterone Level by Liu, Luna, Li, Man, Chen, Pengcheng, Li, Yuchen, Song, Qianmei, Han, Junming, Fang, Li, Guan, Qingbo, Yu, Chunxiao

“…Abstract Introduction: The study aimed to determine if hepatic steatosis assessed by fatty liver index (FLI) was an independent risk factor for male low…”
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The impact of metabolic overweight/obesity phenotypes on unplanned readmission risk in patients with COPD: a retrospective cohort study by Tian, Yang, Liu, Luna, Li, Yuchen, Fan, Xiude, Wu, Wanhong, Shi, Yingzhou, Jiang, Jie, Yuan, Zinuo, Dong, Hang, Li, Huijie, Xuan, Qiuhui, Xu, Chao

“…There is an inconsistent association between overweight/obesity and chronic obstructive pulmonary disease (COPD). Considering that different metabolic…”
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A multiplexed hybrid LC-MS/MS pharmacokinetic assay to measure two co-administered monoclonal antibodies in a clinical study by Xu, Keyang, Liu, Luna, Maia, Mauricio, Li, Jenny, Lowe, John, Song, An, Kaur, Surinder

“…Combination therapies with monoclonal antibodies (mAbs) enhance therapeutic activity and may circumvent drug resistance. However, these studies present…”
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The Predictability of Cystatin C for Peripheral Arterial Disease in Chinese Population with Type 2 Diabetes Mellitus by Liu, Luna, Wang, Hai, Ning, Jing, Han, Junming, Yu, Chunxiao, Guan, Qingbo

“…Objectives. Peripheral artery disease (PAD) in diabetic populations is a vital chronic disease all over the world due to its high morbidity and mortality. It…”
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Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets by Shi, Yingzhou, Dong, Hang, Sun, Shiwei, Wu, Xiaoqin, Fang, Jiansong, Zhao, Jianbo, Han, Junming, Li, Zongyue, Wu, Huixiao, Liu, Luna, Wu, Wanhong, Tian, Yang, Yuan, Guandou, Fan, Xiude, Xu, Chao

“…To evaluate the causal correlation between complement components and non-viral liver diseases and their potential use as druggable targets. We conducted…”
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Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells by Su, Yu, Tian, Zhenhua, Qi, Xiangyu, Luo, Dandan, Liu, Luna, Liu, Shuang, Zheng, Dongmei, Wei, Fang, He, Zhao, Guan, Qingbo

“…Abstract Background Soybean oil is a very common edible oil in daily life. With the changes in the dietary composition, the intake of soybean oil increased…”
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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice by Yang, Leilei, Lu, Peng, Qi, Xiangyu, Yang, Qian, Liu, Luna, Dou, Tao, Guan, Qingbo, Yu, Chunxiao

“…The hypothalamus, as a vital brain region for endocrine and metabolism regulation, undergoes functional disruption during obesity.The anti-aging effect of…”
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Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D by Liu, Moke, Liu, Luna, Guo, Honglin, Fan, Xiude, Liu, Tianbao, Xu, Chao, He, Zhao, Song, Yongfeng, Gao, Ling, Shao, Shanshan, Zhao, Jiajun, Lu, Peng

“…Patients with HNF1A variants may develop liver steatosis, while the underlying mechanism is still unclear. Here, we established a mouse model carrying the…”
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Identification of orally-bioavailable antagonists of the TRPV4 ion-channel by Wei, Zhi-Liang, Nguyen, Margaret T., O’Mahony, Donogh J.R., Acevedo, Alejandra, Zipfel, Sheila, Zhang, Qingling, Liu, Luna, Dourado, Michelle, Chi, Candace, Yip, Victor, DeFalco, Jeff, Gustafson, Amy, Emerling, Daniel E., Kelly, Michael G., Kincaid, John, Vincent, Fabien, Duncton, Matthew A.J.

“…[Display omitted] Antagonists of the TRPV4 receptor were identified using a focused screen, followed by a limited optimization program. The leading compounds…”
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How Different Institutional Logics Affect the Female CEO Gender Effect on IPO Underpricing in China by Liu, Yu Luna, Park, Haemin Dennis, Velamuri, S. Ramakrishna

“…Female entrepreneurs and CEOs generally face greater challenges in securing funding to exploit entrepreneurial opportunities, yet contextual factors under…”
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Critical role of bioanalytical strategies in investigation of clinical PK observations, a Phase I case study by Peng, Kun, Xu, Keyang, Liu, Luna, Hendricks, Robert, Delarosa, Reginald, Erickson, Rich, Budha, Nageshwar, Leabman, Maya, Song, An, Kaur, Surinder, Fischer, Saloumeh K

“…RG7652 is a human immunoglobulin 1 (IgG1) monoclonal antibody (mAb) targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) and is designed for the…”
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High Levels of HER-2 Expression Alter the Ability of Epidermal Growth Factor Receptor (EGFR) Family Tyrosine Kinase Inhibitors to Inhibit EGFR Phosphorylation in Vivo by CHRISTENSEN, James G, SCHRECK, Randall E, MENDEL, Dirk B, CHAN, Emily, XUEYAN WANG, YANG, Chris, LUNA LIU, CUI, Jean, LI SUN, WEI, James, CHERRINGTON, Julie M

“…The epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases have been implicated in the development, progression, and severity of several human…”
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