Search Results - "Liu, Liu‐Yi"
-
1
A Polarity‐Sensitive Ratiometric Fluorescence Probe for Monitoring Changes in Lipid Droplets and Nucleus during Ferroptosis
Published in Angewandte Chemie International Edition (25-06-2021)“…Ferroptosis regulates cell death through reactive oxygen species (ROS)‐associated lipid peroxide accumulation, which is expected to affect the structure and…”
Get full text
Journal Article -
2
Organic‐Platinum Hybrids for Covalent Binding of G‐Quadruplexes: Structural Basis and Application to Cancer Immunotherapy
Published in Angewandte Chemie International Edition (04-09-2023)“…G‐quadruplexes (G4s) have been revived as promising therapeutic targets with the development of immunotherapy, but the G4‐mediated immune response remains…”
Get full text
Journal Article -
3
A Nuclear‐Targeted AIE Photosensitizer for Enzyme Inhibition and Photosensitization in Cancer Cell Ablation
Published in Angewandte Chemie International Edition (04-04-2022)“…The nucleus is considered the ideal target for anti‐tumor therapy because DNA and some enzymes in the nucleus are the main causes of cell canceration and…”
Get full text
Journal Article -
4
Quantitative Detection of G‐Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination
Published in Angewandte Chemie International Edition (08-06-2020)“…G‐quadruplex DNA show structural polymorphism, leading to challenges in the use of selective recognition probes for the accurate detection of G‐quadruplexes in…”
Get full text
Journal Article -
5
Simultaneous Photoactivation of cGAS‐STING Pathway and Pyroptosis by Platinum(II) Triphenylamine Complexes for Cancer Immunotherapy
Published in Angewandte Chemie International Edition (24-10-2022)“…Activation of the cyclic GMP‐AMP synthase‐stimulator of the interferon gene (cGAS‐STING) pathway is a potent anticancer immunotherapeutic strategy, and the…”
Get full text
Journal Article -
6
Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding
Published in Nature communications (29-08-2018)“…DNA G-quadruplexes are not only attractive drug targets for cancer therapeutics, but also have important applications in supramolecular assembly. Here, we…”
Get full text
Journal Article -
7
A code within the genetic code: codon usage regulates co-translational protein folding
Published in Cell communication and signaling (09-09-2020)“…The genetic code is degenerate, and most amino acids are encoded by two to six synonymous codons. Codon usage bias, the preference for certain synonymous…”
Get full text
Journal Article -
8
Multiple‐Color Platinum Complex with Super‐Large Stokes Shift for Super‐Resolution Imaging of Autolysosome Escape
Published in Angewandte Chemie International Edition (19-10-2020)“…It is of great significance to track the platinum drugs in real time with super‐resolution to elucidate their mechanism of action, such as their behavior and…”
Get full text
Journal Article -
9
Spatial Matching Selectivity and Solution Structure of Organic–Metal Hybrid to Quadruplex–Duplex Hybrid
Published in Angewandte Chemie International Edition (13-09-2021)“…The sequence‐dependent DNA secondary structures possess structure polymorphism. To date, studies on regulated ligands mainly focus on individual DNA secondary…”
Get full text
Journal Article -
10
Selectivity and Targeting of G‐Quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics
Published in Angewandte Chemie International Edition (05-07-2021)“…G‐quadruplexes (G4s) are prevalent in oncogenes and are potential antitumor drug targets. However, binding selectivity of compounds to G4s still faces…”
Get full text
Journal Article -
11
Approaches towards understanding the mechanism-of-action of metallodrugs
Published in Coordination chemistry reviews (15-02-2022)“…[Display omitted] •Techniques for studying subcellular localization of metal complexes have been summarized.•Omics strategies for analyzing anti-cancer pathway…”
Get full text
Journal Article -
12
Carbon‐Nanoplated CoS@TiO2 Nanofibrous Membrane: An Interface‐Engineered Heterojunction for High‐Efficiency Electrocatalytic Nitrogen Reduction
Published in Angewandte Chemie International Edition (19-12-2019)“…Developing noble‐metal‐free electrocatalysts is important to industrially viable ammonia synthesis through the nitrogen reduction reaction (NRR). However, the…”
Get full text
Journal Article -
13
Light‐Driven Cascade Mitochondria‐to‐Nucleus Photosensitization in Cancer Cell Ablation
Published in Advanced science (01-04-2021)“…Nuclei and mitochondria are the only cellular organelles containing genes, which are specific targets for efficient cancer therapy. So far, several…”
Get full text
Journal Article -
14
Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G‑Quadruplexes
Published in Journal of the American Chemical Society (06-07-2022)“…The nucleic acid G-quadruplex (G4) has emerged as a promising therapeutic target for a variety of diseases such as cancer and neurodegenerative disease. Among…”
Get full text
Journal Article -
15
The influential factors of urban PM2.5 concentrations in China: a spatial econometric analysis
Published in Journal of cleaner production (20-01-2016)“…Based on the data of PM2.5 concentrations and Air Quality Index of 73 Chinese cities in 2013, this study empirically investigates the socioeconomic influential…”
Get full text
Journal Article -
16
A review of experimental and theoretical research on the deformation and failure behavior of rocks subjected to cyclic loading
Published in Journal of Rock Mechanics and Geotechnical Engineering (01-10-2021)“…Rock engineering is highly susceptible to cyclic loads resulting from earthquakes, quarrying or rockbursts. Acquiring the fatigue properties and failure…”
Get full text
Journal Article -
17
Stable Confinement of Black Phosphorus Quantum Dots on Black Tin Oxide Nanotubes: A Robust, Double‐Active Electrocatalyst toward Efficient Nitrogen Fixation
Published in Angewandte Chemie International Edition (11-11-2019)“…A conceptually new, metal‐free electrocatalyst, black phosphorus (BP) is presented, which is further downsized to quantum dots (QDs) for larger surface areas,…”
Get full text
Journal Article -
18
Synergistically catalytic activities of BiFeO3/TiO2 core-shell nanocomposites for degradation of organic dye molecule through piezophototronic effect
Published in Nano energy (01-02-2019)“…The BiFeO3/TiO2 core-shell nanocomposites with the R3C space group is demonstrated to exhibit the superior synergistically catalyst activities, which is a…”
Get full text
Journal Article -
19
A Continuous Add‐On Probe Reveals the Nonlinear Enlargement of Mitochondria in Light‐Activated Oncosis
Published in Advanced science (01-09-2021)“…Oncosis, depending on DNA damage and mitochondrial swelling, is an important approach for treating cancer and other diseases. However, little is known about…”
Get full text
Journal Article -
20
Deep Reinforcement Learning for Offloading and Resource Allocation in Vehicle Edge Computing and Networks
Published in IEEE transactions on vehicular technology (01-11-2019)“…Mobile Edge Computing (MEC) is a promising technology to extend the diverse services to the edge of Internet of Things (IoT) system. However, the static edge…”
Get full text
Journal Article