Search Results - "Liu, Jielin"
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IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion
Published in The Journal of clinical investigation (01-08-2019)“…Glycosylation of immune receptors and ligands, such as T cell receptor and coinhibitory molecules, regulates immune signaling activation and immune…”
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Construction and preliminary analysis of landslide database triggered by heavy storm in the parallel range-valley area of western Chongqing, China, on 8 June 2017
Published in Frontiers in earth science (Lausanne) (08-08-2024)“…On 8 June 2017, a heavy storm struck the parallel ridge-valley area of western Chongqing, resulting in serious urban waterlogging and landslides, which led to…”
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Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity
Published in Cancer research (Chicago, Ill.) (01-06-2020)“…Abstract Immunotherapies targeting programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand 1 (PD-L1) immune checkpoints represent a major…”
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Recent development of risk-prediction models for incident hypertension: An updated systematic review
Published in PloS one (30-10-2017)“…Hypertension is a leading global health threat and a major cardiovascular disease. Since clinical interventions are effective in delaying the disease…”
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Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment
Published in Cancer discovery (01-04-2020)“…A hallmark of pancreatic ductal adenocarcinoma (PDAC) is an exuberant stroma comprised of diverse cell types that enable or suppress tumor progression. Here,…”
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Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development
Published in PLoS genetics (23-05-2019)“…Dominant mutations of Gata4, an essential cardiogenic transcription factor (TF), were known to cause outflow tract (OFT) defects in both human and mouse, but…”
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Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2017)“…GATA4, an essential cardiogenic transcription factor, provides a model for dominant transcription factor mutations in human disease. Dominant GATA4 mutations…”
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TSG-6+ cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer
Published in Nature communications (10-07-2024)“…Resistance to immune checkpoint therapy (ICT) presents a growing clinical challenge. The tumor microenvironment (TME) and its components, namely…”
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Bisbenzylisoquinoline alkaloid fangchinoline derivative HY-2 inhibits breast cancer cells by suppressing BLM DNA helicase
Published in Biomedicine & pharmacotherapy (31-12-2023)“…The high expression of BLM (Bloom syndrome) DNA helicase in tumors involves its strong association with cell expansion. Bisbenzylisoquinoline alkaloids own an…”
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The effectiveness of selected vegetation communities in regulating runoff and soil loss from regraded gully banks in the Mollisol region of Northeast China
Published in Land degradation & development (15-04-2021)“…The steep slopes of actively developed gullies are extremely sensitive to erosion in the Mollisol region of Northeast China; however, decision making on the…”
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Association study of WNK1 genetic variants and essential hypertension risk in the Northern Han Chinese in Beijing
Published in Frontiers in genetics (15-09-2023)“…Background: Essential hypertension (EH) is a complex disorder resulting from interaction of genetic and environmental factors. Lysine deficient protein kinase…”
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Metagenomics study of soil microorganisms involved in the carbon cycle in a saline-alkaline meadow steppe in the Songnen Plain in Northeast China
Published in Frontiers in microbiology (04-03-2024)“…Soil microorganisms play an important role in regulating and contributing to carbon cycling processes in grassland ecosystems. Soil salinization is one of the…”
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Ratio of carbon and nitrogen in fertilizer treatment drives distinct rhizosphere microbial community composition and co-occurrence networks
Published in Frontiers in microbiology (08-09-2022)“…Fertilization is the main strategy to accelerate vegetation restoration and improve the rhizosphere microbial community in the northeast China. However, the…”
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Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicase
Published in BMC cancer (28-10-2019)“…The high expression of BLM (Bloom syndrome) helicase in tumors involves its strong association with cell expansion. Bisbenzylisoquinoline alkaloids own an…”
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Downregulation of MAL2 inhibits breast cancer progression through regulating β-catenin/c-Myc axis
Published in Cancer cell international (21-07-2023)“…Myelin and lymphocyte protein 2 (MAL2) is mainly involved in endocytosis under physiological conditions and mediates the transport of materials across the…”
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Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity
Published in BMC cancer (02-08-2019)“…MAPK/ERK kinases transmit signals from many growth factors/kinase receptors during normal cell growth/differentiation, and their dysregulation is a hallmark of…”
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Correction to: Bio-electrospraying is a safe technology for delivering human adipose-derived stem cells
Published in Biotechnology letters (01-04-2021)“…In the published version of Fig. 2, images at 1 h 0 kV and 10 kV overlap with image 5 kV. The corrected version of Fig. 2 shows new images for 1 h—0 kV and…”
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Short-Term Artificial Revegetation with Herbaceous Species Can Prevent Soil Degradation in a Black Soil Erosion Gully of Northeast China
Published in Land (Basel) (01-09-2024)“…Understanding the effects of short-term artificial revegetation on preventing soil degradation in erosion gullies of black soil areas is essential to choosing…”
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Association of mitofusin 2 methylation and essential hypertension: a case-control study in a Chinese population
Published in Hypertension research (01-08-2018)“…Mitofusin 2 (Mfn2), a gene that negatively regulates the proliferation of vascular smooth muscle cells (VSMCs), is expressed at low levels in the VSMCs of…”
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Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls
Published in PloS one (28-09-2010)“…No clear consensus has been reached on the alpha-adducin polymorphism (Gly460Trp) and essential hypertension risk. We performed a meta-analysis in an effort to…”
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