Search Results - "Liu, Jessica Aijia"
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Immune Actions on the Peripheral Nervous System in Pain
Published in International journal of molecular sciences (01-02-2021)“…Pain can be induced by tissue injuries, diseases and infections. The interactions between the peripheral nervous system (PNS) and immune system are primary…”
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Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization
Published in Proceedings of the National Academy of Sciences - PNAS (25-02-2020)“…The transcription factor Sox10 is a key regulator in the fate determination of a subpopulation of multipotent trunk neural crest (NC) progenitors toward glial…”
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Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Narirutin via Block of Nav1.7 Voltage-Gated Sodium Channel
Published in International journal of molecular sciences (27-11-2022)“…Neuropathic pain is a refractory chronic disease affecting millions of people worldwide. Given that present painkillers have poor efficacy or severe side…”
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Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
Published in Nature communications (30-10-2017)“…Following epithelial-mesenchymal transition, acquisition of avian trunk neural crest cell (NCC) polarity is prerequisite for directional delamination and…”
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DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3
Published in Advanced science (01-04-2022)“…The ability of melanoma to acquire metastasis through the induction of angiogenesis is one of the major causes of skin cancer death. Here, it is found that…”
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Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury
Published in npj Regenerative medicine (22-03-2024)“…Neural progenitor cells (NPCs) derived from human pluripotent stem cells(hPSCs) provide major cell sources for repairing damaged neural circuitry and enabling…”
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SOX9 is a dose-dependent metastatic fate determinant in melanoma
Published in Journal of experimental & clinical cancer research (14-01-2019)“…In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9…”
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Reprogramming of Mouse Calvarial Osteoblasts into Induced Pluripotent Stem Cells
Published in Stem cells international (01-01-2018)“…Previous studies have demonstrated the ability of reprogramming endochondral bone into induced pluripotent stem (iPS) cells, but whether similar phenomenon…”
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Neural crest stem cells and their potential therapeutic applications
Published in Developmental biology (15-11-2016)“…The neural crest (NC) is a remarkable transient structure generated during early vertebrate development. The neural crest progenitors have extensive migratory…”
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Mode of action of astrocytes in pain: From the spinal cord to the brain
Published in Progress in neurobiology (01-12-2022)“…Chronic pain is a maladaptive condition affecting 7%− 10% of the population worldwide and can be accompanied by depression, anxiety, and insomnia. In…”
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Quercetin, Main Active Ingredient of Moutan Cortex, Alleviates Chronic Orofacial Pain via Block of Voltage-Gated Sodium Channel
Published in Anesthesia and analgesia (01-06-2024)“…Chronic orofacial pain (COP) therapy is challenging, as current medical treatments are extremely lacking. Moutan Cortex (MC) is a traditional Chinese medicine…”
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High-Frequency Spinal Stimulation Suppresses Microglial Kaiso-P2X7 Receptor Axis-Induced Inflammation to Alleviate Neuropathic Pain in Rats
Published in Annals of neurology (01-05-2024)“…Neuropathic pain poses a persistent challenge in clinical management. Neuromodulation has emerged as a last-resort therapy. Conventional spinal cord…”
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Histone deacetylase 5‐induced deficiency of signal transducer and activator of transcription‐3 acetylation contributes to spinal astrocytes degeneration in painful diabetic neuropathy
Published in Glia (01-04-2023)“…Diabetes patients with painful diabetic neuropathy (PDN) show severe spinal atrophy, suggesting pathological changes of the spinal cord contributes to central…”
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Sub-anaesthetic dose of propofol attenuates mechanical allodynia in chronic post-ischaemic pain via regulation of PTEN/PI3K/IL-6 signalling
Published in Molecular pain (01-01-2023)“…Background: Propofol is an intravenous anaesthetic drug that has been shown to reduce inflammatory pain. Complex regional pain syndrome (CRPS) type I is a pain…”
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Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma
Published in Oncogene (14-05-2020)“…A Rho GTPase-activating protein (RhoGAP), deleted in liver cancer 1 (DLC1), is known to function as a tumor suppressor in various cancer types; however,…”
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Comparison of the clinical characteristics and mortalities of severe COVID-19 patients between pre- and post-menopause women and age-matched men
Published in Aging (Albany, NY.) (30-09-2021)“…The mortality rate of young female COVID-19 patients is reported to be lower than that of young males but no significant difference in mortality was found…”
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Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Narirutin via Block of Na v 1.7 Voltage-Gated Sodium Channel
Published in International journal of molecular sciences (27-11-2022)“…Neuropathic pain is a refractory chronic disease affecting millions of people worldwide. Given that present painkillers have poor efficacy or severe side…”
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Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury
Published in Advanced science (01-07-2023)“…Neural stem cells (NSCs) derived from human pluripotent stem cells (hPSCs) are considered a major cell source for reconstructing damaged neural circuitry and…”
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Asymmetric localization of Dlc1 defines trunk neural crest polarity for directional delamination and migration
Published in Mechanisms of development (01-07-2017)Get full text
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