Search Results - "Liu, Hejun"

Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies by Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Wilson, Ian A.

“…Immediately from the outset of the COVID-19 pandemic, researchers from diverse biomedical and biological disciplines have united to study the novel pandemic…”
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Structural basis of a shared antibody response to SARS-CoV-2 by Yuan, Meng, Liu, Hejun, Wu, Nicholas C, Lee, Chang-Chun D, Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F, Landais, Elise, Sok, Devin, Jardine, Joseph G, Burton, Dennis R, Wilson, Ian A

“…Molecular understanding of neutralizing antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine design and…”
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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants by Yuan, Meng, Huang, Deli, Lee, Chang-Chun D, Wu, Nicholas C, Jackson, Abigail M, Zhu, Xueyong, Liu, Hejun, Peng, Linghang, van Gils, Marit J, Sanders, Rogier W, Burton, Dennis R, Reincke, S Momsen, Prüss, Harald, Kreye, Jakob, Nemazee, David, Ward, Andrew B, Wilson, Ian A

“…Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike protein of wild-type severe acute respiratory syndrome coronavirus…”
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Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity by Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.

“…Most antibodies isolated from individuals with coronavirus disease 2019 (COVID-19) are specific to severe acute respiratory syndrome coronavirus 2…”
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Anti-Coking Ni/SiO2 Catalyst for Dry Reforming of Methane: Role of Oleylamine/Oleic Acid Organic Pair by Gao, Xingyuan, Liu, Hejun, Hidajat, Kus, Kawi, Sibudjing

“…We demonstrate the synthesis of silica‐supported Ni catalyst in the presence of oleylamine (OAm) and oleic acid (OAc) as the ligand and surfactant. Compared…”
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An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain by Wu, Nicholas C., Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D., Zhu, Xueyong, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.

“…IGHV3-53-encoded neutralizing antibodies are commonly elicited during SARS-CoV-2 infection and target the receptor-binding domain (RBD) of the spike (S)…”
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Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern by Cho, Hyeseon, Gonzales-Wartz, Kristina Kay, Huang, Deli, Yuan, Meng, Peterson, Mary, Liang, Janie, Beutler, Nathan, Torres, Jonathan L, Cong, Yu, Postnikova, Elena, Bangaru, Sandhya, Talana, Chloe Adrienna, Shi, Wei, Yang, Eun Sung, Zhang, Yi, Leung, Kwanyee, Wang, Lingshu, Peng, Linghang, Skinner, Jeff, Li, Shanping, Wu, Nicholas C, Liu, Hejun, Dacon, Cherrelle, Moyer, Thomas, Cohen, Melanie, Zhao, Ming, Lee, Frances Eun-Hyung, Weinberg, Rona S, Douagi, Iyadh, Gross, Robin, Schmaljohn, Connie, Pegu, Amarendra, Mascola, John R, Holbrook, Michael, Nemazee, David, Rogers, Thomas F, Ward, Andrew B, Wilson, Ian A, Crompton, Peter D, Tan, Joshua

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern threatens the efficacy of existing vaccines and therapeutic…”
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Attentional bias to threat is modulated by stimulus content: an fNIRS study by Liu, Hejun, Zhang, Qihan, Elhai, Jon D, Montag, Christian, Yang, Haibo

“…People are evolutionarily predisposed to associate threat relevant stimuli with fear or aversiveness and show an attentional bias toward threat. Attentional…”
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The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment by Huang, Zhou, Liu, Hejun, Nix, Jay, Xu, Rui, Knoverek, Catherine R., Bowman, Gregory R., Amarasinghe, Gaya K., Sibley, L. David

“…Signal transducer and activator of transcription (STAT) proteins communicate from cell-surface receptors to drive transcription of immune response genes. The…”
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CPNE3 moderates the association between anxiety and working memory by Chen, Chunhui, Wang, Ziyi, Chen, Chuansheng, Xue, Gui, Lu, Shuzhen, Liu, Hejun, Dong, Qi, Zhang, Mingxia

“…Mutual influences between anxiety and working memory (WM) have been extensively studied, and their curvilinear relationship resembles the classic Yerkes-Dodson…”
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Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants by Changrob, Siriruk, Halfmann, Peter J, Liu, Hejun, Torres, Jonathan L, McGrath, Joshua J C, Ozorowski, Gabriel, Li, Lei, Wilbanks, G Dewey, Kuroda, Makoto, Maemura, Tadashi, Huang, Min, Zheng, Nai-Ying, Turner, Hannah L, Erickson, Steven A, Fu, Yanbin, Yasuhara, Atsuhiro, Singh, Gagandeep, Monahan, Brian, Mauldin, Jacob, Srivastava, Komal, Simon, Viviana, Krammer, Florian, Sather, D Noah, Ward, Andrew B, Wilson, Ian A, Kawaoka, Yoshihiro, Wilson, Patrick C

“…The rapid evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants has emphasized the need to identify antibodies with…”
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Analysis of mechanical contact behavior between the catheter and trachea tissue during bronchoscopy by Bao, Yudong, Qu, Shengqian, Qi, Dongbo, Wei, Wen, Zhan, Yang, Liu, Hejun

“…As for the contact mechanics between the catheter and trachea tissue during bronchoscopy, the anterior and curved part of the catheter were selected for…”
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DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration by Luo, Baoming, Yang, Dinghong, Xiao, Xiaoyun, Liu, Hejun, Jiang, Qiongchao, Xu, Yanni, Saw, Phei Er

“…Background. RNA helicases have various essential functions in basically all aspects of RNA metabolism, not only unwinding RNA but also disturbing the…”
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Targeted Imaging of Tumor Associated Macrophages in Breast Cancer by Xu, Yanni, Zeng, Yunting, Xiao, Xiaoyun, Liu, Hejun, Zhou, Boyang, Luo, Baoming, Saw, Phei Er, Jiang, Qiongchao

“…Abstract Breast cancer is a highly heterogeneous disease lacking prognostic markers. Tumor-associated macrophages (TAMs) in the tumor microenvironment are…”
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Neutralizing Antibody Response to Sarbecovirus Is Delayed in Sequential Heterologous Immunization by Lv, Huibin, So, Ray T Y, Teo, Qi Wen, Yuan, Meng, Liu, Hejun, Lee, Chang-Chun D, Yip, Garrick K, Ng, Wilson W, Wilson, Ian A, Peiris, Malik, Wu, Nicholas C, Mok, Chris Ka Pun

“…Antigenic imprinting, which describes the bias of the antibody response due to previous immune history, can influence vaccine effectiveness. While this…”
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Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron by Liu, Hejun, Kaku, Chengzi I., Song, Ge, Yuan, Meng, Andrabi, Raiees, Burton, Dennis R., Walker, Laura M., Wilson, Ian A.

“…Studying the antibody response to SARS-CoV-2 informs on how the human immune system can respond to antigenic variants as well as other SARS-related viruses…”
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Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes by Edwards, Megan R., Liu, Hejun, Shabman, Reed S., Ginell, Garrett M., Luthra, Priya, Ramanan, Parmeshwaran, Keefe, Lisa J., Köllner, Bernd, Amarasinghe, Gaya K., Taylor, Derek J., Leung, Daisy W., Basler, Christopher F.

“…Non-retroviral integrated RNA viral sequences (NIRVs) potentially encoding ∼280 amino acid homologs to filovirus VP35 proteins are present across the Myotis…”
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Ultrasound Molecular Imaging as a Potential Non-invasive Diagnosis to Detect the Margin of Hepatocarcinoma via CSF-1R Targeting by Jiang, Qiongchao, Zeng, Yunting, Xu, Yanni, Xiao, Xiaoyun, Liu, Hejun, Zhou, Boyang, Kong, Yao, Saw, Phei Er, Luo, Baoming

“…Though radiofrequency ablation (RFA) is considered to be an effective treatment for hepatocellular carcinoma (HCC), but more than 30% of patients may suffer…”
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Probing Affinity, Avidity, Anticooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV‑2 Spike by Single Particle Mass Analyses by Yin, Victor, Lai, Szu-Hsueh, Caniels, Tom G, Brouwer, Philip J. M, Brinkkemper, Mitch, Aldon, Yoann, Liu, Hejun, Yuan, Meng, Wilson, Ian A, Sanders, Rogier W, van Gils, Marit J, Heck, Albert J. R

“…Determining how antibodies interact with the spike (S) protein of the SARS-CoV-2 virus is critical for combating COVID-19. Structural studies typically employ…”
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Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago by Qiang, Min, Ma, Peixiang, Li, Yu, Liu, Hejun, Harding, Adam, Min, Chenyu, Wang, Fulian, Liu, Lili, Yuan, Meng, Ji, Qun, Tao, Pingdong, Shi, Xiaojie, Li, Zhean, Li, Teng, Wang, Xian, Zhang, Yu, Wu, Nicholas C., Lee, Chang‐Chun D., Zhu, Xueyong, Gilbert‐Jaramillo, Javier, Zhang, Chuyue, Saxena, Abhishek, Huang, Xingxu, Wang, Hou, James, William, Dwek, Raymond A., Wilson, Ian A., Yang, Guang, Lerner, Richard A.

“…Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, but enable documentation of the history of antibody…”
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