Search Results - "Liu, Haihan"
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Spatiotemporal Differences and Classification Regulation of Urbanization Impact on Agricultural Development in Shrinking Areas: A Case Study of 15 Shrinking Cities in Three Provinces of Northeast China
Published in Chinese geographical science (01-12-2023)“…Studying the impact of urbanization on agricultural development in shrinking areas is important for maintaining food security and promoted agricultural…”
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Structural requirement of RARγ agonism through computational aspects
Published in Journal of molecular modeling (01-04-2023)“…Context RARγ is a therapeutic target for many skin diseases and has potential in cancer treatment. In the current study, we put forward a comprehensive…”
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Clinical effect of external application of Rutongyu medicine film in the treatment of hyperplasia of mammary gland (乳痛愈药膜治疗乳腺增生病临床疗效观察)
Published in 中西医结合护理 (28-04-2023)“…Objective To observe the clinical effect of external application of Rutongyu medicine film in the treatment of hyperplasia of mammary gland. Methods Totally 96…”
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A synthetic Schlieren method for laboratory measuring density profiles of a stratified fluid
Published in Experimental thermal and fluid science (01-08-2024)“…A synthetic Schlieren method is developed to measure the density field of a stratified fluid. A transparent sheet of background markers is attached on one side…”
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Multifunctional absorbents for oily pollution control and mechanistic insights with theoretical simulation
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-09-2023)“…[Display omitted] •For the first time, Salvia miltiorrhiza residues were converted into aerogels.•The maximum absorption ability of aerogels was achieved at…”
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Thermal conductivity of filled composite materials considering interactions between fillers
Published in Applied thermal engineering (01-08-2018)“…•The 10% is the inflection point and percolation threshold for cube fillers with ideal filler contacts.•The contacts and shapes of fillers are considered.•A…”
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Docking Score ML: Target-Specific Machine Learning Models Improving Docking-Based Virtual Screening in 155 Targets
Published in Journal of chemical information and modeling (22-07-2024)“…In drug discovery, molecular docking methods face challenges in accurately predicting energy. Scoring functions used in molecular docking often fail to…”
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Design, synthesis, pharmacological evaluation, and computational study of benzo[d] isothiazol-based small molecule inhibitors targeting PD-1/PD-l1 interaction
Published in European journal of medicinal chemistry (05-09-2024)“…Blockade of the programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway is an attractive strategy for immunotherapy, but the clinical…”
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Computational characteristics of the structure-activity relationship of inhibitors targeting Pks13-TE domain
Published in Computational biology and chemistry (01-06-2023)“…Multiple studies have established the Pks13-TE domain as a promising target for anti-tuberculosis drug development. However, recent findings have revealed that…”
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Optimization of Thermal Insulation Performance for the Porous Materials
Published in Heat transfer engineering (08-11-2018)“…Porous materials are widely used in porous media filtration, membrane separation, catalyst substrates, solid fuel cells, insulation, and other fields. When the…”
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Dynamic transfer and driving mechanisms of the coupling and coordination of agricultural resilience and rural land use efficiency in China
Published in Journal of geographical sciences (01-08-2024)“…The joint study of agriculture and rural areas is of great significance for safeguarding agricultural development, revitalizing rural areas, and enhancing…”
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FaissMolLib: An efficient and easy deployable tool for ligand-based virtual screening
Published in Computational biology and chemistry (01-06-2024)“…Virtual screening-based molecular similarity and fingerprint are crucial in drug design, target prediction, and ADMET prediction, aiding in identifying…”
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Insights into β3-adrenoceptor agonism through comprehensive in silico investigation
Published in Computational biology and chemistry (01-06-2023)“…Research onβ3-AR, the new member of the adrenoceptor family, is in its infancy and few β3-AR agonists have been approved for marketing to date. Meanwhile,…”
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Spatiotemporal Differences and Classification Regulation of Urbaniza-tion Impact on Agricultural Development in Shrinking Areas:A Case Study of 15 Shrinking Cities in Three Provinces of Northeast China
Published in 中国地理科学(英文版) (2023)“…Studying the impact of urbanization on agricultural development in shrinking areas is important for maintaining food security and promoted agricultural…”
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Discovery of a novel and selective cathepsin L inhibitor with anti-metastatic ability in vitro and in vivo against breast cancer cells
Published in Bioorganic chemistry (01-10-2021)“…[Display omitted] •Forty-four B-ring derivatives of asperphenamate were designed and synthesized.•Compound B-2a displayed a good selectivity against cathepsin…”
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Diagnosis Accuracy and Prognostic Significance of the Dickkopf-1 Protein in Gastrointestinal Carcinomas: Systematic Review and Network Meta-analysis
Published in Journal of Cancer (01-01-2020)“…Objective: To evaluate the diagnosis accuracy and prognostic significance of bio-marker dickkopf-1(DKK-1) protein in GIC, and also sub-type of hepatocellular…”
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Journal Article Book Review -
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Design, synthesis, pharmacological evaluation, and computational study of benzod isothiazol-based small molecule inhibitors targeting PD-1/PD-l1 interaction
Published in European journal of medicinal chemistry (05-09-2024)“…Blockade of the programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway is an attractive strategy for immunotherapy, but the clinical…”
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Journal Article -
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Insights into β 3 -adrenoceptor agonism through comprehensive in silico investigation
Published in Computational biology and chemistry (01-06-2023)“…Research onβ -AR, the new member of the adrenoceptor family, is in its infancy and few β -AR agonists have been approved for marketing to date. Meanwhile, β…”
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Montmorillonite powder combined with liquid dressing and nursing management for a patient with bacterial pneumonia complicated by perianal incontinence dermatitis (1例细菌性肺炎并发肛周失禁性皮炎患者采用蒙脱石散联合液体敷料换药的护理体会)
Published in 中西医结合护理 (01-03-2023)“…This paper reviewed the clinical data of a patient with bacterial pneumonia who developed perianal incontinence dermatitis during treatment. The patient was…”
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